These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

133 related articles for article (PubMed ID: 9192967)

  • 1. SN-38, a metabolite of the camptothecin derivative CPT-11, potentiates the cytotoxic effect of radiation in human colon adenocarcinoma cells grown as spheroids.
    Omura M; Torigoe S; Kubota N
    Radiother Oncol; 1997 May; 43(2):197-201. PubMed ID: 9192967
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Intracellular roles of SN-38, a metabolite of the camptothecin derivative CPT-11, in the antitumor effect of CPT-11.
    Kawato Y; Aonuma M; Hirota Y; Kuga H; Sato K
    Cancer Res; 1991 Aug; 51(16):4187-91. PubMed ID: 1651156
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Antitumor activity of a camptothecin derivative, CPT-11, against human tumor xenografts in nude mice.
    Kawato Y; Furuta T; Aonuma M; Yasuoka M; Yokokura T; Matsumoto K
    Cancer Chemother Pharmacol; 1991; 28(3):192-8. PubMed ID: 1855276
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Interaction of irinotecan (CPT-11) and its active metabolite 7-ethyl-10-hydroxycamptothecin (SN-38) with human cytochrome P450 enzymes.
    Hanioka N; Ozawa S; Jinno H; Tanaka-Kagawa T; Nishimura T; Ando M; Sawada Ji J
    Drug Metab Dispos; 2002 Apr; 30(4):391-6. PubMed ID: 11901092
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of potentially lethal and sublethal damage repair by camptothecin and etoposide in human melanoma cell lines.
    Ng CE; Bussey AM; Raaphorst GP
    Int J Radiat Biol; 1994 Jul; 66(1):49-57. PubMed ID: 8027612
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Adenoviral vector-mediated expression of a gene encoding secreted, EpCAM-targeted carboxylesterase-2 sensitises colon cancer spheroids to CPT-11.
    Oosterhoff D; Overmeer RM; de Graaf M; van der Meulen IH; Giaccone G; van Beusechem VW; Haisma HJ; Pinedo HM; Gerritsen WR
    Br J Cancer; 2005 Mar; 92(5):882-7. PubMed ID: 15756257
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synergistic effects of topoisomerase I inhibitor, 7-ethyl-10-hydroxycamptothecin, and irradiation in a cisplatin-resistant human small cell lung cancer cell line.
    Kohara H; Tabata M; Kiura K; Ueoka H; Kawata K; Chikamori M; Aoe K; Chikamori K; Matsushita A; Harada M
    Clin Cancer Res; 2002 Jan; 8(1):287-92. PubMed ID: 11801571
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification and kinetics of a beta-glucuronide metabolite of SN-38 in human plasma after administration of the camptothecin derivative irinotecan.
    Rivory LP; Robert J
    Cancer Chemother Pharmacol; 1995; 36(2):176-9. PubMed ID: 7767955
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effects of SN-38 (an active metabolite of CPT-11) on responses of human and rodent cells to irradiation.
    Sasai K; Guo GZ; Shibuya K; Oya N; Shibata T; Nagata Y; Hiraoka M
    Int J Radiat Oncol Biol Phys; 1998 Nov; 42(4):785-8. PubMed ID: 9845096
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of a new metabolite of CPT-11 (irinotecan): pharmacological properties and activation to SN-38.
    Dodds HM; Haaz MC; Riou JF; Robert J; Rivory LP
    J Pharmacol Exp Ther; 1998 Jul; 286(1):578-83. PubMed ID: 9655905
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Comparison of topoisomerase I inhibition, DNA damage, and cytotoxicity of camptothecin derivatives presently in clinical trials.
    Tanizawa A; Fujimori A; Fujimori Y; Pommier Y
    J Natl Cancer Inst; 1994 Jun; 86(11):836-42. PubMed ID: 8182764
    [TBL] [Abstract][Full Text] [Related]  

  • 12. CPT-11 in human colon-cancer cell lines and xenografts: characterization of cellular sensitivity determinants.
    Jansen WJ; Zwart B; Hulscher ST; Giaccone G; Pinedo HM; Boven E
    Int J Cancer; 1997 Jan; 70(3):335-40. PubMed ID: 9033637
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effect of CPT-11 in combination with other anticancer agents in lung cancer cells.
    Pei XH; Nakanishi Y; Takayama K; Bai F; Kawasaki M; Tsuruta N; Mizuno K; Hara N
    Anticancer Drugs; 1997 Mar; 8(3):231-7. PubMed ID: 9095327
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 7-Ethyl-10-[4-(1-piperidino)-1-piperidino] carbonyloxy camptothecin: mechanism of resistance and clinical trials.
    Saijo N; Nishio K; Kubota N; Kanzawa F; Shinkai T; Karato A; Sasaki Y; Eguchi K; Tamura T; Ohe Y
    Cancer Chemother Pharmacol; 1994; 34 Suppl():S112-7. PubMed ID: 8070019
    [TBL] [Abstract][Full Text] [Related]  

  • 15. P53 status plays no role in radiosensitizing effects of SN-38, a camptothecin derivative.
    Xie X; Sasai K; Shibuya K; Tachiiri S; Nihei K; Ohnishi T; Hiraoka M
    Cancer Chemother Pharmacol; 2000; 45(5):362-8. PubMed ID: 10803918
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Phase I and pharmacological study of the novel topoisomerase I inhibitor 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (CPT-11) administered as a ninety-minute infusion every 3 weeks.
    Rowinsky EK; Grochow LB; Ettinger DS; Sartorius SE; Lubejko BG; Chen TL; Rock MK; Donehower RC
    Cancer Res; 1994 Jan; 54(2):427-36. PubMed ID: 8275479
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of cis-diamminedichloroplatinum (II)-induced DNA interstrand cross-link removal by 7-ethyl-10-hydroxy-camptothecin in HST-1 human squamous-carcinoma cells.
    Masumoto N; Nakano S; Esaki T; Fujishima H; Tatsumoto T; Niho Y
    Int J Cancer; 1995 Jul; 62(1):70-5. PubMed ID: 7601570
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Camptothecin analog (CPT-11)-sensitive human pancreatic tumor cell line QGP-1N shows resistance to SN-38, an active metabolite of CPT-11.
    Takeda S; Shimazoe T; Kuga H; Sato K; Kono A
    Biochem Biophys Res Commun; 1992 Oct; 188(1):70-7. PubMed ID: 1329748
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hydrolysis of irinotecan and its oxidative metabolites, 7-ethyl-10-[4-N-(5-aminopentanoic acid)-1-piperidino] carbonyloxycamptothecin and 7-ethyl-10-[4-(1-piperidino)-1-amino]-carbonyloxycamptothecin, by human carboxylesterases CES1A1, CES2, and a newly expressed carboxylesterase isoenzyme, CES3.
    Sanghani SP; Quinney SK; Fredenburg TB; Davis WI; Murry DJ; Bosron WF
    Drug Metab Dispos; 2004 May; 32(5):505-11. PubMed ID: 15100172
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Enhancement of tumor radio-response by irinotecan in human lung tumor xenografts.
    Tamura K; Takada M; Kawase I; Tada T; Kudoh S; Okishio K; Fukuoka M; Yamaoka N; Fujiwara Y; Yamakido M
    Jpn J Cancer Res; 1997 Feb; 88(2):218-23. PubMed ID: 9119752
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.