127 related articles for article (PubMed ID: 9199660)
1. Synthesis, DNA binding and cytotoxicity of 1-[[omega-(9-acridinyl)amino]alkyl]carbonyl -3-(chloromethyl)-6-hydroxyindolines, a new class of DNA-targeted alkylating agents.
Fan JY; Tercel M; Denny WA
Anticancer Drug Des; 1997 Jun; 12(4):277-93. PubMed ID: 9199660
[TBL] [Abstract][Full Text] [Related]
2. DNA-Directed alkylating agents. 7. Synthesis, DNA interaction, and antitumor activity of bis(hydroxymethyl)- and bis(carbamate)-substituted pyrrolizines and imidazoles.
Atwell GJ; Fan JY; Tan K; Denny WA
J Med Chem; 1998 Nov; 41(24):4744-54. PubMed ID: 9822545
[TBL] [Abstract][Full Text] [Related]
3. DNA minor groove targeted alkylating agents based on bisbenzimidazole carriers: synthesis, cytotoxicity and sequence-specificity of DNA alkylation.
Smaill JB; Fan JY; Denny WA
Anticancer Drug Des; 1998 Dec; 13(8):857-80. PubMed ID: 10335264
[TBL] [Abstract][Full Text] [Related]
4. Sequence selectivity, cross-linking efficiency and cytotoxicity of DNA-targeted 4-anilinoquinoline aniline mustards.
McClean S; Costelloe C; Denny WA; Searcey M; Wakelin LP
Anticancer Drug Des; 1999 Jun; 14(3):187-204. PubMed ID: 10500495
[TBL] [Abstract][Full Text] [Related]
5. Synthesis of 1-substituted 3-(chloromethyl)-6-aminoindoline (6-amino-seco-CI) DNA minor groove alkylating agents and structure-activity relationships for their cytotoxicity.
Milbank JB; Tercel M; Atwell GJ; Wilson WR; Hogg A; Denny WA
J Med Chem; 1999 Feb; 42(4):649-58. PubMed ID: 10052972
[TBL] [Abstract][Full Text] [Related]
6. Design, synthesis, and biological evaluation of DNA sequence and minor groove selective alkylating agents.
Lee M; Rhodes AL; Wyatt MD; Forrow S; Hartley JA
Anticancer Drug Des; 1993 Jun; 8(3):173-92. PubMed ID: 8517912
[TBL] [Abstract][Full Text] [Related]
7. Sequence-specific DNA interactions by novel alkylating anthracycline derivatives.
Marchini S; Gonzalez Paz O; Ripamonti M; Geroni C; Bargiotti A; Caruso M; Todeschi S; D'Incalci M; Broggini M
Anticancer Drug Des; 1995 Dec; 10(8):641-53. PubMed ID: 8595123
[TBL] [Abstract][Full Text] [Related]
8. Aniline mustard analogues of the DNA-intercalating agent amsacrine: DNA interaction and biological activity.
Fan JY; Valu KK; Woodgate PD; Baguley BC; Denny WA
Anticancer Drug Des; 1997 Apr; 12(3):181-203. PubMed ID: 9154110
[TBL] [Abstract][Full Text] [Related]
9. Cytotoxicity and DNA interaction of the enantiomers of 6-amino-3-(chloromethyl)-1-[(5,6,7-trimethoxyindol-2-yl)carbonyl]indo- line (amino-seco-CI-TMI).
Tercel M; Gieseg MA; Milbank JB; Boyd M; Fan JY; Tan LK; Wilson WR; Denny WA
Chem Res Toxicol; 1999 Aug; 12(8):700-6. PubMed ID: 10458703
[TBL] [Abstract][Full Text] [Related]
10. The role of base excision repair in the repair of DNA adducts formed by a series of nitrogen mustard-containing analogues of distamycin of increasing binding site size.
Brooks N; McHugh PJ; Lee M; Hartley JA
Anticancer Drug Des; 1999 Feb; 14(1):11-8. PubMed ID: 10363024
[TBL] [Abstract][Full Text] [Related]
11. Design, synthesis, DNA sequence preferential alkylation and biological evaluation of N-mustard derivatives of distamycin and netropsin analogues.
Xie G; Gupta R; Lown JW
Anticancer Drug Des; 1995 Jul; 10(5):389-409. PubMed ID: 7639929
[TBL] [Abstract][Full Text] [Related]
12. Comparison of the patterns of DNA alkylation by phenol and amino seco-CBI-TMI compounds: use of a PCR method for the facile preparation of single end-labelled double-stranded DNA.
Gieseg MA; Matejovic J; Denny WA
Anticancer Drug Des; 1999 Feb; 14(1):77-84. PubMed ID: 10363030
[TBL] [Abstract][Full Text] [Related]
13. Novel DNA-directed alkylating agents consisting of naphthalimide, nitrogen mustard and lexitropsin moieties: synthesis, DNA sequence specificity and biological evaluation.
Gupta R; Liu J; Xie G; Lown JW
Anticancer Drug Des; 1996 Dec; 11(8):581-96. PubMed ID: 9022747
[TBL] [Abstract][Full Text] [Related]
14. C-H to N substitution dramatically alters the sequence-specific DNA alkylation, cytotoxicity, and expression of human cancer cell lines.
Bando T; Narita A; Iwai A; Kihara K; Sugiyama H
J Am Chem Soc; 2004 Mar; 126(11):3406-7. PubMed ID: 15025451
[TBL] [Abstract][Full Text] [Related]
15. Combinatorial identification of a novel consensus sequence for the covalent DNA-binding polyamide tallimustine.
Sunavala-Dossabhoy G; Van Dyke MW
Biochemistry; 2005 Feb; 44(7):2510-22. PubMed ID: 15709763
[TBL] [Abstract][Full Text] [Related]
16. 5-Amino-1-(chloromethyl)-1,2-dihydro-3H-benz[e]indoles: relationships between structure and cytotoxicity for analogues bearing different DNA minor groove binding subunits.
Atwell GJ; Milbank JJ; Wilson WR; Hogg A; Denny WA
J Med Chem; 1999 Aug; 42(17):3400-11. PubMed ID: 10464026
[TBL] [Abstract][Full Text] [Related]
17. Distribution of furamidine analogues in tumor cells: targeting of the nucleus or mitochondria depending on the amidine substitution.
Lansiaux A; Tanious F; Mishal Z; Dassonneville L; Kumar A; Stephens CE; Hu Q; Wilson WD; Boykin DW; Bailly C
Cancer Res; 2002 Dec; 62(24):7219-29. PubMed ID: 12499262
[TBL] [Abstract][Full Text] [Related]
18. Synthesis of new bifunctional compounds which selectively alkylate guanines in DNA.
Henderson ND; Lacy SM; O'Hare CC; Hartley JA; McClean S; Wakelin LP; Kelland LR; Robins DJ
Anticancer Drug Des; 1998 Oct; 13(7):749-68. PubMed ID: 9807160
[TBL] [Abstract][Full Text] [Related]
19. Polybenzamide mustards: structure-activity relationships for DNA sequence-specific alkylation.
Turner PR; Ferguson LR; Denny WA
Anticancer Drug Des; 1999 Feb; 14(1):61-70. PubMed ID: 10363028
[TBL] [Abstract][Full Text] [Related]
20. The DNA intercalating alkaloid cryptolepine interferes with topoisomerase II and inhibits primarily DNA synthesis in B16 melanoma cells.
Bonjean K; De Pauw-Gillet MC; Defresne MP; Colson P; Houssier C; Dassonneville L; Bailly C; Greimers R; Wright C; Quetin-Leclercq J; Tits M; Angenot L
Biochemistry; 1998 Apr; 37(15):5136-46. PubMed ID: 9548744
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
