BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

245 related articles for article (PubMed ID: 9201940)

  • 1. Mutational analysis of 26 residues of vaccinia DNA topoisomerase identifies Ser-204 as important for DNA binding and cleavage.
    Wang LK; Wittschieben J; Shuman S
    Biochemistry; 1997 Jul; 36(26):7944-50. PubMed ID: 9201940
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mutations within a conserved region of vaccinia topoisomerase affect the DNA cleavage-religation equilibrium.
    Petersen BO; Wittschieben J; Shuman S
    J Mol Biol; 1996 Oct; 263(2):181-95. PubMed ID: 8913300
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mutational analysis of 39 residues of vaccinia DNA topoisomerase identifies Lys-220, Arg-223, and Asn-228 as important for covalent catalysis.
    Cheng C; Wang LK; Sekiguchi J; Shuman S
    J Biol Chem; 1997 Mar; 272(13):8263-9. PubMed ID: 9079646
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Deletions at the carboxyl terminus of vaccinia DNA topoisomerase affect DNA binding and enhance distributivity in DNA relaxation.
    Wang LK; Shuman S
    Biochemistry; 1997 Apr; 36(13):3909-16. PubMed ID: 9092821
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mutational analysis of vaccinia virus topoisomerase identifies residues involved in DNA binding.
    Sekiguchi J; Shuman S
    Nucleic Acids Res; 1997 Sep; 25(18):3649-56. PubMed ID: 9278486
    [TBL] [Abstract][Full Text] [Related]  

  • 6. p-Thiophenylalanine-induced DNA cleavage and religation activity of a modified vaccinia topoisomerase IB.
    Chen S; Zhang Y; Hecht SM
    Biochemistry; 2011 Nov; 50(43):9340-51. PubMed ID: 21942719
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Vaccinia topoisomerase mutants illuminate roles for Phe59, Gly73, Gln69 and Phe215.
    Tian L; Shuman S
    Virology; 2007 Mar; 359(2):466-76. PubMed ID: 17059840
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Melanoplus sanguinipes entomopoxvirus DNA topoisomerase: site-specific DNA transesterification and effects of 5'-bridging phosphorothiolates.
    Krogh BO; Cheng C; Burgin A; Shuman S
    Virology; 1999 Nov; 264(2):441-51. PubMed ID: 10562506
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Deciphering the distinct role for the metal coordination motif in the catalytic activity of Mycobacterium smegmatis topoisomerase I.
    Bhat AG; Leelaram MN; Hegde SM; Nagaraja V
    J Mol Biol; 2009 Nov; 393(4):788-802. PubMed ID: 19733176
    [TBL] [Abstract][Full Text] [Related]  

  • 10. DNA contacts by protein domains of the molluscum contagiosum virus type-1B topoisomerase.
    Hwang Y; Park M; Fischer WH; Burgin A; Bushman F
    Virology; 1999 Sep; 262(2):479-91. PubMed ID: 10502526
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mechanism of DNA transesterification by vaccinia topoisomerase: catalytic contributions of essential residues Arg-130, Gly-132, Tyr-136 and Lys-167.
    Wittschieben J; Shuman S
    Nucleic Acids Res; 1997 Aug; 25(15):3001-8. PubMed ID: 9224599
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Vaccinia DNA topoisomerase I: evidence supporting a free rotation mechanism for DNA supercoil relaxation.
    Stivers JT; Harris TK; Mildvan AS
    Biochemistry; 1997 Apr; 36(17):5212-22. PubMed ID: 9136883
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Histidine 265 is important for covalent catalysis by vaccinia topoisomerase and is conserved in all eukaryotic type I enzymes.
    Petersen BO; Shuman S
    J Biol Chem; 1997 Feb; 272(7):3891-6. PubMed ID: 9020090
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A catalytic domain of eukaryotic DNA topoisomerase I.
    Cheng C; Shuman S
    J Biol Chem; 1998 May; 273(19):11589-95. PubMed ID: 9565576
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ribonuclease activity of vaccinia DNA topoisomerase IB: kinetic and high-throughput inhibition studies using a robust continuous fluorescence assay.
    Kwon K; Nagarajan R; Stivers JT
    Biochemistry; 2004 Nov; 43(47):14994-5004. PubMed ID: 15554707
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Peptide inhibitors of DNA cleavage by tyrosine recombinases and topoisomerases.
    Klemm M; Cheng C; Cassell G; Shuman S; Segall AM
    J Mol Biol; 2000 Jun; 299(5):1203-16. PubMed ID: 10873446
    [TBL] [Abstract][Full Text] [Related]  

  • 17. SFV topoisomerase: sequence specificity in a genetically mapped interval.
    Palaniyar N; Fisher C; Parks R; Evans DH
    Virology; 1996 Jul; 221(2):351-4. PubMed ID: 8661446
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Chemical and traditional mutagenesis of vaccinia DNA topoisomerase provides insights to cleavage site recognition and transesterification chemistry.
    Yakovleva L; Chen S; Hecht SM; Shuman S
    J Biol Chem; 2008 Jun; 283(23):16093-103. PubMed ID: 18367446
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Individual nucleotide bases, not base pairs, are critical for triggering site-specific DNA cleavage by vaccinia topoisomerase.
    Tian L; Sayer JM; Jerina DM; Shuman S
    J Biol Chem; 2004 Sep; 279(38):39718-26. PubMed ID: 15252055
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Chlorella virus Marburg topoisomerase II: high DNA cleavage activity as a characteristic of Chlorella virus type II enzymes.
    Dickey JS; Choi TJ; Van Etten JL; Osheroff N
    Biochemistry; 2005 Mar; 44(10):3899-908. PubMed ID: 15751965
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.