BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

623 related articles for article (PubMed ID: 9202243)

  • 1. Tyrosine residues in the C-terminal domain of the insulin-like growth factor-I receptor mediate mitogenic and tumorigenic signals.
    Esposito DL; Blakesley VA; Koval AP; Scrimgeour AG; LeRoith D
    Endocrinology; 1997 Jul; 138(7):2979-88. PubMed ID: 9202243
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mitogen-activated protein kinase and phosphatidylinositol 3-kinase pathways are not sufficient for insulin-like growth factor I-induced mitogenesis and tumorigenesis.
    Scrimgeour AG; Blakesley VA; Stannard BS; LeRoith D
    Endocrinology; 1997 Jun; 138(6):2552-8. PubMed ID: 9165048
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tamoxifen interferes with the insulin-like growth factor I receptor (IGF-IR) signaling pathway in breast cancer cells.
    Guvakova MA; Surmacz E
    Cancer Res; 1997 Jul; 57(13):2606-10. PubMed ID: 9205064
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tumorigenic and mitogenic capacities are reduced in transfected fibroblasts expressing mutant insulin-like growth factor (IGF)-I receptors. The role of tyrosine residues 1250, 1251, and 1316 in the carboxy-terminus of the IGF-I receptor.
    Blakesley VA; Kalebic T; Helman LJ; Stannard B; Faria TN; Roberts CT; LeRoith D
    Endocrinology; 1996 Feb; 137(2):410-7. PubMed ID: 8593783
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dissociation of mitogenesis and transforming activity by C-terminal truncation of the insulin-like growth factor-I receptor.
    Surmacz E; Sell C; Swantek J; Kato H; Roberts CT; LeRoith D; Baserga R
    Exp Cell Res; 1995 May; 218(1):370-80. PubMed ID: 7737373
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Involvement of Raf-1 kinase and protein kinase C zeta in insulin-like growth factor I-induced brown adipocyte mitogenic signaling cascades: inhibition by cyclic adenosine 3',5'-monophosphate.
    Valverde AM; Teruel T; Lorenzo M; Benito M
    Endocrinology; 1996 Sep; 137(9):3832-41. PubMed ID: 8756554
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The insulin-like growth factor I receptor-induced interaction of insulin receptor substrate-4 and Crk-II.
    Karas M; Koval AP; Zick Y; LeRoith D
    Endocrinology; 2001 May; 142(5):1835-40. PubMed ID: 11316748
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Activation of the insulin-like growth factor 1 signaling pathway by the antiapoptotic agents aurintricarboxylic acid and evans blue.
    Beery R; Haimsohn M; Wertheim N; Hemi R; Nir U; Karasik A; Kanety H; Geier A
    Endocrinology; 2001 Jul; 142(7):3098-107. PubMed ID: 11416032
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Differential regulation of insulin receptor substrate-2 and mitogen-activated protein kinase tyrosine phosphorylation by phosphatidylinositol 3-kinase inhibitors in SH-SY5Y human neuroblastoma cells.
    Kim B; Leventhal PS; White MF; Feldman EL
    Endocrinology; 1998 Dec; 139(12):4881-9. PubMed ID: 9832424
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Insulin receptor substrate-1 enhances growth hormone-induced proliferation.
    Liang L; Zhou T; Jiang J; Pierce JH; Gustafson TA; Frank SJ
    Endocrinology; 1999 May; 140(5):1972-83. PubMed ID: 10218944
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Roles of insulin receptor substrate-1 and Shc on insulin-like growth factor I receptor signaling in early passages of cultured human fibroblasts.
    Takahashi Y; Tobe K; Kadowaki H; Katsumata D; Fukushima Y; Yazaki Y; Akanuma Y; Kadowaki T
    Endocrinology; 1997 Feb; 138(2):741-50. PubMed ID: 9003010
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Neoplastic transformation induced by insulin receptor substrate-1 overexpression requires an interaction with both Grb2 and Syp signaling molecules.
    Tanaka S; Ito T; Wands JR
    J Biol Chem; 1996 Jun; 271(24):14610-6. PubMed ID: 8662827
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Insulin receptor substrate (IRS) proteins IRS-1 and IRS-2 differential signaling in the insulin/insulin-like growth factor-I pathways in fetal brown adipocytes.
    Valverde AM; Lorenzo M; Pons S; White MF; Benito M
    Mol Endocrinol; 1998 May; 12(5):688-97. PubMed ID: 9605931
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Increased insulin sensitivity in IGF-I receptor--deficient brown adipocytes.
    Mur C; Valverde AM; Kahn CR; Benito M
    Diabetes; 2002 Mar; 51(3):743-54. PubMed ID: 11872675
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Essential role of insulin-like growth factor I receptor in insulin-induced fetal brown adipocyte differentiation.
    Mur C; Arribas M; Benito M; Valverde AM
    Endocrinology; 2003 Feb; 144(2):581-93. PubMed ID: 12538620
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Replacement of tyrosine 1251 in the carboxyl terminus of the insulin-like growth factor-I receptor disrupts the actin cytoskeleton and inhibits proliferation and anchorage-independent growth.
    Blakesley VA; Koval AP; Stannard BS; Scrimgeour A; LeRoith D
    J Biol Chem; 1998 Jul; 273(29):18411-22. PubMed ID: 9660809
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ret oncogene signal transduction via a IRS-2/PI 3-kinase/PKB and a SHC/Grb-2 dependent pathway: possible implication for transforming activity in NIH3T3 cells.
    Hennige AM; Lammers R; Arlt D; Höppner W; Strack V; Niederfellner G; Seif FJ; Häring HU; Kellerer M
    Mol Cell Endocrinol; 2000 Sep; 167(1-2):69-76. PubMed ID: 11000521
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Antiinsulin receptor autoantibodies induce insulin receptors to constitutively associate with insulin receptor substrate-1 and -2 and cause severe cell resistance to both insulin and insulin-like growth factor I.
    Auclair M; Vigouroux C; Desbois-Mouthon C; Deibener J; Kaminski P; Lascols O; Cherqui G; Capeau J; Caron M
    J Clin Endocrinol Metab; 1999 Sep; 84(9):3197-206. PubMed ID: 10487687
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Different pathways of postreceptor desensitization following chronic insulin treatment and in cells overexpressing constitutively active insulin receptors.
    Inoue G; Cheatham B; Kahn CR
    J Biol Chem; 1996 Nov; 271(45):28206-11. PubMed ID: 8910437
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Insulin and insulin-like growth factor-I receptors similarly stimulate deoxyribonucleic acid synthesis despite differences in cellular protein tyrosine phosphorylation.
    Mastick CC; Kato H; Roberts CT; LeRoith D; Saltiel AR
    Endocrinology; 1994 Jul; 135(1):214-22. PubMed ID: 7516864
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 32.