BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

126 related articles for article (PubMed ID: 9202738)

  • 1. Assessing human risk to heterocyclic amines.
    Gooderham NJ; Murray S; Lynch AM; Yadollahi-Farsani M; Zhao K; Rich K; Boobis AR; Davies DS
    Mutat Res; 1997 May; 376(1-2):53-60. PubMed ID: 9202738
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Systemic exposure to dietary heterocyclic amines in man.
    Davies DS; Gooderham NJ; Murray S; Lynch A; de la Torre R; Segura J; Boobis AR
    Princess Takamatsu Symp; 1995; 23():190-6. PubMed ID: 8844810
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Chemical methods for assessing systemic exposure to dietary heterocyclic amines in man.
    Davies DS; Gooderham NJ; Murray S; Lynch A; de la Torre R; Segura J; Boobis AR
    Arch Toxicol Suppl; 1996; 18():251-8. PubMed ID: 8678801
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Heterocyclic amines: evaluation of their role in diet associated human cancer.
    Gooderham NJ; Murray S; Lynch AM; Edwards RJ; Yadollahi-Farsani M; Bratt C; Rich KJ; Zhao K; Murray BP; Bhadresa S; Crosbie SJ; Boobis AR; Davies DS
    Br J Clin Pharmacol; 1996 Jul; 42(1):91-8. PubMed ID: 8807149
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Enzymatic studies of the activation of heterocyclic food mutagens in man.
    Boobis AR; Gooderham NJ; Rich KJ; Zhao K; Edwards RJ; Murray BP; Lynch AM; Murray S; Davies DS
    Princess Takamatsu Symp; 1995; 23():134-44. PubMed ID: 8844804
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Metabolism of heterocyclic aromatic amines by human hepatocytes and cytochrome P4501A2.
    Turesky RJ; Guengerich FP; Guillouzo A; Langouët S
    Mutat Res; 2002 Sep; 506-507():187-95. PubMed ID: 12351158
    [TBL] [Abstract][Full Text] [Related]  

  • 7. N-hydroxy-MeIQx is the major microsomal oxidation product of the dietary carcinogen MeIQx with human liver.
    Rich KJ; Murray BP; Lewis I; Rendell NB; Davies DS; Gooderham NJ; Boobis AR
    Carcinogenesis; 1992 Dec; 13(12):2221-6. PubMed ID: 1473228
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Contribution of CYP1A1 and CYP1A2 to the activation of heterocyclic amines in monkeys and human.
    Edwards RJ; Murray BP; Murray S; Schulz T; Neubert D; Gant TW; Thorgeirsson SS; Boobis AR; Davies DS
    Carcinogenesis; 1994 May; 15(5):829-36. PubMed ID: 8200083
    [TBL] [Abstract][Full Text] [Related]  

  • 9. CYP1A2-catalyzed conversion of dietary heterocyclic amines to their proximate carcinogens is their major route of metabolism in humans.
    Boobis AR; Lynch AM; Murray S; de la Torre R; Solans A; Farré M; Segura J; Gooderham NJ; Davies DS
    Cancer Res; 1994 Jan; 54(1):89-94. PubMed ID: 8261468
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Activation and effects of the food-derived heterocyclic amines in extrahepatic tissues.
    Overvik E; Hellmold H; Branting C; Gustafsson JA
    Princess Takamatsu Symp; 1995; 23():123-33. PubMed ID: 8844803
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Metabolism of the food derived mutagen and carcinogen 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine (PhIP) by human liver microsomes.
    Zhao K; Murray S; Davies DS; Boobis AR; Gooderham NJ
    Carcinogenesis; 1994 Jun; 15(6):1285-8. PubMed ID: 8020169
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Regioselective differences in C(8)- and N-oxidation of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline by human and rat liver microsomes and cytochromes P450 1A2.
    Turesky RJ; Parisod V; Huynh-Ba T; Langouët S; Guengerich FP
    Chem Res Toxicol; 2001 Jul; 14(7):901-11. PubMed ID: 11453738
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Intra- and interindividual variability in systemic exposure in humans to 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline and 2-amino-1-methyl- 6-phenylimidazo[4,5-b]pyridine, carcinogens present in cooked beef.
    Lynch AM; Knize MG; Boobis AR; Gooderham NJ; Davies DS; Murray S
    Cancer Res; 1992 Nov; 52(22):6216-23. PubMed ID: 1423264
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Factors affecting human heterocyclic amine intake and the metabolism of PhIP.
    Knize MG; Kulp KS; Salmon CP; Keating GA; Felton JS
    Mutat Res; 2002 Sep; 506-507():153-62. PubMed ID: 12351155
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Activation of heterocyclic aromatic amines by rat and human liver microsomes and by purified rat and human cytochrome P450 1A2.
    Turesky RJ; Constable A; Richoz J; Varga N; Markovic J; Martin MV; Guengerich FP
    Chem Res Toxicol; 1998 Aug; 11(8):925-36. PubMed ID: 9705755
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Binding of mutagenic heterocyclic amines by intestinal and lactic acid bacteria.
    Orrhage K; Sillerström E; Gustafsson JA; Nord CE; Rafter J
    Mutat Res; 1994 Dec; 311(2):239-48. PubMed ID: 7526189
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Metabolites of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine (PhIP) in human urine after consumption of charbroiled or fried beef.
    Strickland PT; Qian Z; Friesen MD; Rothman N; Sinha R
    Mutat Res; 2002 Sep; 506-507():163-73. PubMed ID: 12351156
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mutagenic activation of IQ, PhIP and MeIQx by hepatic microsomes from rat, monkey and man: low mutagenic activation of MeIQx in cynomolgus monkeys in vitro reflects low DNA adduct levels in vivo.
    Davis CD; Schut HA; Adamson RH; Thorgeirsson UP; Thorgeirsson SS; Snyderwine EG
    Carcinogenesis; 1993 Jan; 14(1):61-5. PubMed ID: 8425272
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Metabolic processing and disposition of 2-amino-3-methylimidazo[4,5-f] quinoline (IQ), 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx), and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in nonhuman primates.
    Snyderwine EG; Turesky RJ; Buonarati MH; Turteltaub KW; Adamson RH
    Princess Takamatsu Symp; 1995; 23():69-77. PubMed ID: 8844797
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Urinary excretion of unmetabolized and phase II conjugates of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in humans: relationship to cytochrome P4501A2 and N-acetyltransferase activity.
    Stillwell WG; Kidd LC; Wishnok JS; Tannenbaum SR; Sinha R
    Cancer Res; 1997 Aug; 57(16):3457-64. PubMed ID: 9270013
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.