BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

364 related articles for article (PubMed ID: 9202739)

  • 1. Human acetyltransferase polymorphisms.
    Grant DM; Hughes NC; Janezic SA; Goodfellow GH; Chen HJ; Gaedigk A; Yu VL; Grewal R
    Mutat Res; 1997 May; 376(1-2):61-70. PubMed ID: 9202739
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases.
    Hein DW; Doll MA; Rustan TD; Gray K; Feng Y; Ferguson RJ; Grant DM
    Carcinogenesis; 1993 Aug; 14(8):1633-8. PubMed ID: 8353847
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Metabolic activation of N-hydroxy-2-aminofluorene and N-hydroxy-2-acetylaminofluorene by monomorphic N-acetyltransferase (NAT1) and polymorphic N-acetyltransferase (NAT2) in colon cytosols of Syrian hamsters congenic at the NAT2 locus.
    Hein DW; Doll MA; Gray K; Rustan TD; Ferguson RJ
    Cancer Res; 1993 Feb; 53(3):509-14. PubMed ID: 8425184
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Molecular genetics and function of NAT1 and NAT2: role in aromatic amine metabolism and carcinogenesis.
    Hein DW
    Mutat Res; 2002 Sep; 506-507():65-77. PubMed ID: 12351146
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Monomorphic and polymorphic human arylamine N-acetyltransferases: a comparison of liver isozymes and expressed products of two cloned genes.
    Grant DM; Blum M; Beer M; Meyer UA
    Mol Pharmacol; 1991 Feb; 39(2):184-91. PubMed ID: 1996083
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Acetylation of putative arylamine and alkylaniline carcinogens in immortalized human fibroblasts transfected with rapid and slow acetylator N-acetyltransferase 2 haplotypes.
    Leggett CS; Doll MA; States JC; Hein DW
    Arch Toxicol; 2021 Jan; 95(1):311-319. PubMed ID: 33136180
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Genetic polymorphism in N-Acetyltransferase (NAT): Population distribution of NAT1 and NAT2 activity.
    Walker K; Ginsberg G; Hattis D; Johns DO; Guyton KZ; Sonawane B
    J Toxicol Environ Health B Crit Rev; 2009; 12(5-6):440-72. PubMed ID: 20183529
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effect of arylamine acetyltransferase Nat3 gene knockout on N-acetylation in the mouse.
    Sugamori KS; Brenneman D; Wong S; Gaedigk A; Yu V; Abramovici H; Rozmahel R; Grant DM
    Drug Metab Dispos; 2007 Jul; 35(7):1064-70. PubMed ID: 17403913
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Genetic variants of N-acetyltransferases 1 and 2 (NAT1 and NAT2) in cynomolgus and rhesus macaques.
    Uno Y; Murayama N; Yamazaki H
    Biochem Pharmacol; 2020 Jul; 177():113996. PubMed ID: 32339492
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Arylamine N-acetyltransferases: structural and functional implications of polymorphisms.
    Sim E; Lack N; Wang CJ; Long H; Westwood I; Fullam E; Kawamura A
    Toxicology; 2008 Dec; 254(3):170-83. PubMed ID: 18852012
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cloning, sequencing, and recombinant expression of NAT1, NAT2, and NAT3 derived from the C3H/HeJ (rapid) and A/HeJ (slow) acetylator inbred mouse: functional characterization of the activation and deactivation of aromatic amine carcinogens.
    Fretland AJ; Doll MA; Gray K; Feng Y; Hein DW
    Toxicol Appl Pharmacol; 1997 Feb; 142(2):360-6. PubMed ID: 9070359
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effects of N-acetyl transferase 1 and 2 polymorphisms on bladder cancer risk in Caucasians.
    Gu J; Liang D; Wang Y; Lu C; Wu X
    Mutat Res; 2005 Mar; 581(1-2):97-104. PubMed ID: 15725609
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 4-Aminobiphenyl downregulation of NAT2 acetylator genotype-dependent N- and O-acetylation of aromatic and heterocyclic amine carcinogens in primary mammary epithelial cell cultures from rapid and slow acetylator rats.
    Jefferson FA; Xiao GH; Hein DW
    Toxicol Sci; 2009 Jan; 107(1):293-7. PubMed ID: 18842621
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Polymorphic NATs and cancer predisposition.
    Hirvonen A
    IARC Sci Publ; 1999; (148):251-70. PubMed ID: 10493262
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Placental expression of arylamine N-acetyltransferases: evidence for linkage disequilibrium between NAT1*10 and NAT2*4 alleles of the two human arylamine N-acetyltransferase loci NAT1 and NAT2.
    Smelt VA; Mardon HJ; Sim E
    Pharmacol Toxicol; 1998 Oct; 83(4):149-57. PubMed ID: 9820875
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Generation and functional characterization of arylamine N-acetyltransferase Nat1/Nat2 double-knockout mice.
    Sugamori KS; Wong S; Gaedigk A; Yu V; Abramovici H; Rozmahel R; Grant DM
    Mol Pharmacol; 2003 Jul; 64(1):170-9. PubMed ID: 12815173
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Molecular genetics and epidemiology of the NAT1 and NAT2 acetylation polymorphisms.
    Hein DW; Doll MA; Fretland AJ; Leff MA; Webb SJ; Xiao GH; Devanaboyina US; Nangju NA; Feng Y
    Cancer Epidemiol Biomarkers Prev; 2000 Jan; 9(1):29-42. PubMed ID: 10667461
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pharmacogenetics of the human arylamine N-acetyltransferases.
    Grant DM; Goodfellow GH; Sugamori K; Durette K
    Pharmacology; 2000 Sep; 61(3):204-11. PubMed ID: 10971207
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Regulation of the activity of the human drug metabolizing enzyme arylamine N-acetyltransferase 1: role of genetic and non genetic factors.
    Rodrigues-Lima F; Dupret JM
    Curr Pharm Des; 2004; 10(20):2519-24. PubMed ID: 15320760
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Metabolic activation of heterocyclic aromatic amines catalyzed by human arylamine N-acetyltransferase isozymes (NAT1 and NAT2) expressed in Salmonella typhimurium.
    Wild D; Feser W; Michel S; Lord HL; Josephy PD
    Carcinogenesis; 1995 Mar; 16(3):643-8. PubMed ID: 7697826
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.