BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

91 related articles for article (PubMed ID: 9203632)

  • 1. Correlation between the formation of cleavable complex with topoisomerase I and growth-inhibitory activity for saintopin-type antibiotics.
    Fujii N; Yamashita Y; Mizukami T; Nakano H
    Mol Pharmacol; 1997 Feb; 51(2):269-76. PubMed ID: 9203632
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Induction of mammalian DNA topoisomerase I and II mediated DNA cleavage by saintopin, a new antitumor agent from fungus.
    Yamashita Y; Kawada S; Fujii N; Nakano H
    Biochemistry; 1991 Jun; 30(24):5838-45. PubMed ID: 1646001
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Drug-induced down-regulation of topoisomerase I in human epidermoid cancer cells resistant to saintopin and camptothecins.
    Taniguchi K; Kohno K; Kawanami K; Wada M; Kanematsu T; Kuwano M
    Cancer Res; 1996 May; 56(10):2348-54. PubMed ID: 8625310
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Saintopin, a new antitumor antibiotic with topoisomerase II dependent DNA cleavage activity, from Paecilomyces.
    Yamashita Y; Saitoh Y; Ando K; Takahashi K; Ohno H; Nakano H
    J Antibiot (Tokyo); 1990 Oct; 43(10):1344-6. PubMed ID: 2175304
    [No Abstract]   [Full Text] [Related]  

  • 5. Novel selective inhibitors for human topoisomerase I, BM2419-1 and -2 derived from saintopin.
    Ishiyama D; Futamata K; Futamata M; Kasuya O; Kamo S; Yamashita F; Kanazawa S
    J Antibiot (Tokyo); 1998 Dec; 51(12):1069-74. PubMed ID: 10048564
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Saintopin, a dual inhibitor of DNA topoisomerases I and II, as a probe for drug-enzyme interactions.
    Leteurtre F; Fujimori A; Tanizawa A; Chhabra A; Mazumder A; Kohlhagen G; Nakano H; Pommier Y
    J Biol Chem; 1994 Nov; 269(46):28702-7. PubMed ID: 7961822
    [TBL] [Abstract][Full Text] [Related]  

  • 7. UCE6, a new antitumor antibiotic with topoisomerase I mediated DNA cleavage activity, from actinomycetes.
    Fujii N; Yamashita Y; Chiba S; Uosaki Y; Saitoh Y; Tuji Y; Nakano H
    J Antibiot (Tokyo); 1993 Jul; 46(7):1173-4. PubMed ID: 8395492
    [No Abstract]   [Full Text] [Related]  

  • 8. UCE6, a new antitumor antibiotic with topoisomerase I-mediated DNA cleavage activity produced by actinomycetes: producing organism, fermentation, isolation and biological activity.
    Fujii N; Tanaka F; Yamashita Y; Ashizawa T; Chiba S; Nakano H
    J Antibiot (Tokyo); 1997 Jun; 50(6):490-5. PubMed ID: 9268005
    [TBL] [Abstract][Full Text] [Related]  

  • 9. UCE1022, a new antitumor antibiotic with topoisomerase I mediated DNA cleavage activity, from Paecilomyces.
    Fujii N; Yamashita Y; Ando K; Agatsuma T; Saitoh Y; Gomi K; Nishiie Y; Nakano H
    J Antibiot (Tokyo); 1994 Aug; 47(8):949-51. PubMed ID: 7928685
    [No Abstract]   [Full Text] [Related]  

  • 10. Identification of mammalian DNA topoisomerase I as an intracellular target of the anticancer drug camptothecin.
    Hsiang YH; Liu LF
    Cancer Res; 1988 Apr; 48(7):1722-6. PubMed ID: 2832051
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Induction of mammalian DNA topoisomerase I mediated DNA cleavage by antitumor indolocarbazole derivatives.
    Yamashita Y; Fujii N; Murakata C; Ashizawa T; Okabe M; Nakano H
    Biochemistry; 1992 Dec; 31(48):12069-75. PubMed ID: 1333791
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mechanism of cytotoxicity of N-[2-(dimethylamino)ethyl] acridine-4-carboxamide and of its 7-chloro derivative: the roles of topoisomerases I and II.
    Bridewell DJ; Finlay GJ; Baguley BC
    Cancer Chemother Pharmacol; 1999; 43(4):302-8. PubMed ID: 10071981
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effects of morpholinyl doxorubicins, doxorubicin, and actinomycin D on mammalian DNA topoisomerases I and II.
    Wassermann K; Markovits J; Jaxel C; Capranico G; Kohn KW; Pommier Y
    Mol Pharmacol; 1990 Jul; 38(1):38-45. PubMed ID: 2164630
    [TBL] [Abstract][Full Text] [Related]  

  • 14. DNA topoisomerase II as the primary target of anti-tumor anthracyclines.
    Zunino F; Capranico G
    Anticancer Drug Des; 1990 Nov; 5(4):307-17. PubMed ID: 1963303
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effect of topoisomerase poisoning by antitumor drugs VM 26, fostriecin and camptothecin on DNA repair replication by mammalian cell extracts.
    Frosina G; Rossi O
    Carcinogenesis; 1992 Aug; 13(8):1371-7. PubMed ID: 1323426
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [Antitumor agents targeting mammalian topoisomerases].
    Nakano H
    Gan To Kagaku Ryoho; 1991 Aug; 18(10):1550-5. PubMed ID: 1651681
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Topoisomerase II-mediated DNA cleavage activity and irreversibility of cleavable complex formation induced by DNA intercalator with alkylating capability.
    Kong XB; Rubin L; Chen LI; Ciszewska G; Watanabe KA; Tong WP; Sirotnak FM; Chou TC
    Mol Pharmacol; 1992 Feb; 41(2):237-44. PubMed ID: 1311406
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Induction of topoisomerase I-mediated DNA cleavage by a new indolocarbazole, ED-110.
    Yoshinari T; Yamada A; Uemura D; Nomura K; Arakawa H; Kojiri K; Yoshida E; Suda H; Okura A
    Cancer Res; 1993 Feb; 53(3):490-4. PubMed ID: 8381047
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Aclacinomycin A stabilizes topoisomerase I covalent complexes.
    Nitiss JL; Pourquier P; Pommier Y
    Cancer Res; 1997 Oct; 57(20):4564-9. PubMed ID: 9377570
    [TBL] [Abstract][Full Text] [Related]  

  • 20. DNA cleavage by topoisomerase I in the presence of indolocarbazole derivatives of rebeccamycin.
    Bailly C; Riou JF; Colson P; Houssier C; Rodrigues-Pereira E; Prudhomme M
    Biochemistry; 1997 Apr; 36(13):3917-29. PubMed ID: 9092822
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.