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2. Dietary glycine prevents increases in hepatocyte proliferation caused by the peroxisome proliferator WY-14,643. Rose ML; Germolec D; Arteel GE; Schoonhoven R; Thurman RG Chem Res Toxicol; 1997 Oct; 10(10):1198-204. PubMed ID: 9348444 [TBL] [Abstract][Full Text] [Related]
3. Development of hepatocellular carcinomas and increased peroxisomal fatty acid beta-oxidation in rats fed [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio] acetic acid (Wy-14,643) in the semipurified diet. Lalwani ND; Reddy MK; Qureshi SA; Reddy JK Carcinogenesis; 1981; 2(7):645-50. PubMed ID: 7273344 [TBL] [Abstract][Full Text] [Related]
4. Relationship of hepatic peroxisome proliferation and replicative DNA synthesis to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid (Wy-14,643) in rats. Marsman DS; Cattley RC; Conway JG; Popp JA Cancer Res; 1988 Dec; 48(23):6739-44. PubMed ID: 3180084 [TBL] [Abstract][Full Text] [Related]
5. Differential induction and regulation of peroxisomal enzymes: predictive value of peroxisome proliferation in identifying certain nonmutagenic carcinogens. Nemali MR; Reddy MK; Usuda N; Reddy PG; Comeau LD; Rao MS; Reddy JK Toxicol Appl Pharmacol; 1989 Jan; 97(1):72-87. PubMed ID: 2916237 [TBL] [Abstract][Full Text] [Related]
6. Characteristics of the hepatocarcinogenesis caused by dehydroepiandrosterone, a peroxisome proliferator, in male F-344 rats. Hayashi F; Tamura H; Yamada J; Kasai H; Suga T Carcinogenesis; 1994 Oct; 15(10):2215-9. PubMed ID: 7955056 [TBL] [Abstract][Full Text] [Related]
7. Specific changes in the protein composition of rat liver in response to the peroxisome proliferators ciprofibrate, Wy-14,643 and di-(2-ethylhexyl)phthalate. Watanabe T; Lalwani ND; Reddy JK Biochem J; 1985 May; 227(3):767-75. PubMed ID: 4004798 [TBL] [Abstract][Full Text] [Related]
8. WY-14,643 induced cell proliferation and oxidative stress in mouse liver are independent of NADPH oxidase. Woods CG; Burns AM; Bradford BU; Ross PK; Kosyk O; Swenberg JA; Cunningham ML; Rusyn I Toxicol Sci; 2007 Aug; 98(2):366-74. PubMed ID: 17483499 [TBL] [Abstract][Full Text] [Related]
9. Toxicity studies of WY-14,643 (CAS No. 50892-23-4) administered in feed to male Sprague-Dawley rats, B6C3F1 mice, and Syrian hamsters. Cunningham ML Toxic Rep Ser; 2007 Oct; (62):1-136. PubMed ID: 24743700 [TBL] [Abstract][Full Text] [Related]
10. Immunochemical identity of peroxisomal enoyl-CoA hydratase with the peroxisome-proliferation-associated 80,000 mol wt polypeptide in rat liver. Reddy MK; Qureshi SA; Hollenberg PF; Reddy JK J Cell Biol; 1981 Jun; 89(3):406-17. PubMed ID: 6788778 [TBL] [Abstract][Full Text] [Related]
11. Conjugated linoleic acid activates peroxisome proliferator-activated receptor alpha and beta subtypes but does not induce hepatic peroxisome proliferation in Sprague-Dawley rats. Moya-Camarena SY; Van den Heuvel JP; Belury MA Biochim Biophys Acta; 1999 Jan; 1436(3):331-42. PubMed ID: 9989264 [TBL] [Abstract][Full Text] [Related]
12. Peroxisome proliferation and lipid peroxidation in rat liver. Goel SK; Lalwani ND; Reddy JK Cancer Res; 1986 Mar; 46(3):1324-30. PubMed ID: 3943099 [TBL] [Abstract][Full Text] [Related]
13. Hepatic effects of some [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio] acetic acid (WY-14,643) analogs in the mouse. Reddy JK; Moody DE; Azarnoff DL; Tomarelli RM Arch Int Pharmacodyn Ther; 1977 Jan; 225(1):51-7. PubMed ID: 851495 [TBL] [Abstract][Full Text] [Related]
14. Relationship of oxidative damage to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and Wy-14,643. Conway JG; Tomaszewski KE; Olson MJ; Cattley RC; Marsman DS; Popp JA Carcinogenesis; 1989 Mar; 10(3):513-9. PubMed ID: 2924396 [TBL] [Abstract][Full Text] [Related]
15. Induction of sister chromatid exchange and micronuclei in primary cultures of rat and human hepatocytes by the peroxisome proliferator, Wy-14,643. Hwang JJ; Hsia MT; Jirtle RL Mutat Res; 1993 Apr; 286(2):123-33. PubMed ID: 7681523 [TBL] [Abstract][Full Text] [Related]
16. Mechanisms of extrahepatic tumor induction by peroxisome proliferators in male CD rats. Biegel LB; Hurtt ME; Frame SR; O'Connor JC; Cook JC Toxicol Sci; 2001 Mar; 60(1):44-55. PubMed ID: 11222872 [TBL] [Abstract][Full Text] [Related]
17. Potent peroxisome proliferators inhibit beta-oxidation in the isolated perfused rat liver. Bojes HK; Thurman RG Toxicol Appl Pharmacol; 1996 Oct; 140(2):322-7. PubMed ID: 8887448 [TBL] [Abstract][Full Text] [Related]
18. Enhancement by peroxisome proliferators of the susceptibility to DNA damage in the liver of male F344 rats. Hayashi F; Tamura H; Watanabe T; Suga T Cancer Lett; 1995 May; 92(1):87-90. PubMed ID: 7757964 [TBL] [Abstract][Full Text] [Related]
19. Increased nuclear ploidy, not cell proliferation, is sustained in the peroxisome proliferator-treated rat liver. Lalwani ND; Dethloff LA; Haskins JR; Robertson DG; de la Iglesia FA Toxicol Pathol; 1997; 25(2):165-76. PubMed ID: 9125775 [TBL] [Abstract][Full Text] [Related]
20. Kupffer cells are causally responsible for the mitogenic effect of peroxisome proliferators. Rose ML; Germolec DR; Schoonhoven R; Thurman RG Carcinogenesis; 1997 Aug; 18(8):1453-6. PubMed ID: 9276615 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]