These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

618 related articles for article (PubMed ID: 9221818)

  • 1. Species and strain differences in the hepatic cytochrome P450-mediated biotransformation of 1,4-dichlorobenzene.
    Hissink AM; Oudshoorn MJ; Van Ommen B; Van Bladeren PJ
    Toxicol Appl Pharmacol; 1997 Jul; 145(1):1-9. PubMed ID: 9221818
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Differences in cytochrome P450-mediated biotransformation of 1,2-dichlorobenzene by rat and man: implications for human risk assessment.
    Hissink AM; Oudshoorn MJ; Van Ommen B; Haenen GR; Van Bladeren PJ
    Chem Res Toxicol; 1996 Dec; 9(8):1249-56. PubMed ID: 8951226
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cytochrome P450 catalyzed oxidation of monochlorobenzene, 1,2- and 1,4-dichlorobenzene in rat, mouse, and human liver microsomes.
    Nedelcheva V; Gut I; Soucek P; Frantík E
    Chem Biol Interact; 1998 Aug; 115(1):53-70. PubMed ID: 9817075
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Role of 3,4-dichlorophenyl methyl sulfone, a metabolite of o-dichlorobenzene, in the changes in hepatic microsomal drug-metabolizing enzymes caused by o-dichlorobenzene administration in rats.
    Kato Y; Kimura R
    Toxicol Appl Pharmacol; 1997 Aug; 145(2):277-84. PubMed ID: 9266800
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A physiologically based pharmacokinetic (PB-PK) model for 1,2-dichlorobenzene linked to two possible parameters of toxicity.
    Hissink AM; Van Ommen B; Krüse J; Van Bladeren PJ
    Toxicol Appl Pharmacol; 1997 Aug; 145(2):301-10. PubMed ID: 9266803
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dose-dependent kinetics and metabolism of 1,2-dichlorobenzene in rat: effect of pretreatment with phenobarbital.
    Hissink AM; Van Ommen B; Van Bladeren PJ
    Xenobiotica; 1996 Jan; 26(1):89-105. PubMed ID: 8851824
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Biotransformation of phenol to hydroquinone and catechol by rat liver microsomes.
    Sawahata T; Neal RA
    Mol Pharmacol; 1983 Mar; 23(2):453-60. PubMed ID: 6835203
    [TBL] [Abstract][Full Text] [Related]  

  • 8. NTP technical report on the toxicity and metabolism studies of chloral hydrate (CAS No. 302-17-0). Administered by gavage to F344/N rats and B6C3F1 mice.
    Beland FA
    Toxic Rep Ser; 1999 Aug; (59):1-66, A1-E7. PubMed ID: 11803702
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effect of hyperthyroidism on the in vitro metabolism and covalent binding of 1,1-dichloroethylene in rat liver microsomes.
    Gunasena GH; Kanz MF
    J Toxicol Environ Health; 1997 Oct; 52(2):169-88. PubMed ID: 9310148
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The metabolism of pentachlorobenzene by rat liver microsomes: the nature of the reactive intermediates formed.
    den Besten C; Peters MM; van Bladeren PJ
    Biochem Biophys Res Commun; 1989 Sep; 163(3):1275-81. PubMed ID: 2675838
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The different genotoxicity of p-dichlorobenzene in mouse and rat: measurement of the in vivo and in vitro covalent interaction with nucleic acids.
    Lattanzi G; Bartoli S; Bonora B; Colacci A; Grilli S; Niero A; Mazzullo M
    Tumori; 1989 Aug; 75(4):305-10. PubMed ID: 2479159
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Comparison of the hepatic and renal effects of 1,4-dichlorobenzene in the rat and mouse.
    Lake BG; Cunninghame ME; Price RJ
    Fundam Appl Toxicol; 1997 Sep; 39(1):67-75. PubMed ID: 9325029
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hepatic epoxide concentrations during biotransformation of 1,2- and 1,4-dichlorobenzene: the use of in vitro and in vivo metabolism, kinetics and PB-PK modeling.
    Hissink E; van Ommen B; Bogaards JJ; van Bladeren PJ
    Adv Exp Med Biol; 1996; 387():129-33. PubMed ID: 8794204
    [No Abstract]   [Full Text] [Related]  

  • 14. In vitro metabolism and covalent binding of ethylbenzene to microsomal protein as a possible mechanism of ethylbenzene-induced mouse lung tumorigenesis.
    Saghir SA; Zhang F; Rick DL; Kan L; Bus JS; Bartels MJ
    Regul Toxicol Pharmacol; 2010; 57(2-3):129-35. PubMed ID: 20096743
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterization of verlukast metabolites arising from an epoxide intermediate produced with hepatic microsomes from beta-naphthoflavone-treated rodents (P-4501A1).
    Nicoll-Griffith DA; Chauret N; Yergey JA; Trimble LA; Favreau L; Zamboni R; Grossman SJ; Drey J; Herold E
    Drug Metab Dispos; 1993; 21(5):861-7. PubMed ID: 7902249
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Bioactivation of chloroform in hepatic microsomes from rodent strains susceptible or resistant to CHCl3 carcinogenicity.
    Testai E; Gemma S; Vittozzi L
    Toxicol Appl Pharmacol; 1992 Jun; 114(2):197-203. PubMed ID: 1609411
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Stereochemical aspects of vinylcyclohexene bioactivation in rodent hepatic microsomes and purified human cytochrome P450 enzyme systems.
    Fontaine SM; Mash EA; Hoyer PB; Sipes IG
    Drug Metab Dispos; 2001 Feb; 29(2):179-84. PubMed ID: 11159809
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Comparison of the biotransformation of 1,3-butadiene and its metabolite, butadiene monoepoxide, by hepatic and pulmonary tissues from humans, rats and mice.
    Csanády GA; Guengerich FP; Bond JA
    Carcinogenesis; 1992 Jul; 13(7):1143-53. PubMed ID: 1638680
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Metabolism of 2-amino-alpha-carboline. A food-borne heterocyclic amine mutagen and carcinogen by human and rodent liver microsomes and by human cytochrome P4501A2.
    Raza H; King RS; Squires RB; Guengerich FP; Miller DW; Freeman JP; Lang NP; Kadlubar FF
    Drug Metab Dispos; 1996 Apr; 24(4):395-400. PubMed ID: 8801053
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The acute hepatotoxicity of the isomers of dichlorobenzene in Fischer-344 and Sprague-Dawley rats: isomer-specific and strain-specific differential toxicity.
    Stine ER; Gunawardhana L; Sipes IG
    Toxicol Appl Pharmacol; 1991 Jul; 109(3):472-81. PubMed ID: 1853346
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 31.