These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

201 related articles for article (PubMed ID: 9223340)

  • 21. Metabolism of presenilin 1: influence of presenilin 1 on amyloid precursor protein processing.
    Borchelt DR
    Neurobiol Aging; 1998; 19(1 Suppl):S15-8. PubMed ID: 9562461
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Presenilin-1 mutations associated with familial Alzheimer's disease do not disrupt protein transport from the endoplasmic reticulum to the Golgi apparatus.
    Tan Y; Hong J; Doan T; McConlogue L; Maltese WA
    Biochim Biophys Acta; 1998 Jul; 1407(1):69-78. PubMed ID: 9639678
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Stable association of presenilin derivatives and absence of presenilin interactions with APP.
    Thinakaran G; Regard JB; Bouton CM; Harris CL; Price DL; Borchelt DR; Sisodia SS
    Neurobiol Dis; 1998 Apr; 4(6):438-53. PubMed ID: 9666482
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Role of presenilin in gamma-secretase cleavage of amyloid precursor protein.
    Xia W
    Exp Gerontol; 2000 Jul; 35(4):453-60. PubMed ID: 10959033
    [TBL] [Abstract][Full Text] [Related]  

  • 25. FAD mutations in presenilin-1 or amyloid precursor protein decrease the efficacy of a gamma-secretase inhibitor: evidence for direct involvement of PS1 in the gamma-secretase cleavage complex.
    Xia W; Ostaszewski BL; Kimberly WT; Rahmati T; Moore CL; Wolfe MS; Selkoe DJ
    Neurobiol Dis; 2000 Dec; 7(6 Pt B):673-81. PubMed ID: 11114265
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Regulation of amyloid precursor protein processing by presenilin 1 (PS1) and PS2 in PS1 knockout cells.
    Palacino JJ; Berechid BE; Alexander P; Eckman C; Younkin S; Nye JS; Wolozin B
    J Biol Chem; 2000 Jan; 275(1):215-22. PubMed ID: 10617607
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Subcellular compartment and molecular subdomain of beta-amyloid precursor protein relevant to the Abeta 42-promoting effects of Alzheimer mutant presenilin 2.
    Iwata H; Tomita T; Maruyama K; Iwatsubo T
    J Biol Chem; 2001 Jun; 276(24):21678-85. PubMed ID: 11283011
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Specificity of presenilin-1- and presenilin-2-dependent γ-secretases towards substrate processing.
    Stanga S; Vrancx C; Tasiaux B; Marinangeli C; Karlström H; Kienlen-Campard P
    J Cell Mol Med; 2018 Feb; 22(2):823-833. PubMed ID: 28994238
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Presenilin-1-mediated retention of APP derivatives in early biosynthetic compartments.
    Réchards M; Xia W; Oorschot V; van Dijk S; Annaert W; Selkoe DJ; Klumperman J
    Traffic; 2006 Mar; 7(3):354-64. PubMed ID: 16497228
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Aspartyl protease inhibitor pepstatin binds to the presenilins of Alzheimer's disease.
    Evin G; Sharples RA; Weidemann A; Reinhard FB; Carbone V; Culvenor JG; Holsinger RM; Sernee MF; Beyreuther K; Masters CL
    Biochemistry; 2001 Jul; 40(28):8359-68. PubMed ID: 11444983
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Presenilins and Alzheimer's disease: biological functions and pathogenic mechanisms.
    Czech C; Tremp G; Pradier L
    Prog Neurobiol; 2000 Mar; 60(4):363-84. PubMed ID: 10670705
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Presenilin clinical mutations can affect gamma-secretase activity by different mechanisms.
    Bentahir M; Nyabi O; Verhamme J; Tolia A; Horré K; Wiltfang J; Esselmann H; De Strooper B
    J Neurochem; 2006 Feb; 96(3):732-42. PubMed ID: 16405513
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Analysis of Non-Amyloidogenic Mutations in APP Supports Loss of Function Hypothesis of Alzheimer's Disease.
    Kim M; Bezprozvanny I
    Int J Mol Sci; 2023 Jan; 24(3):. PubMed ID: 36768421
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Photoactivated gamma-secretase inhibitors directed to the active site covalently label presenilin 1.
    Li YM; Xu M; Lai MT; Huang Q; Castro JL; DiMuzio-Mower J; Harrison T; Lellis C; Nadin A; Neduvelil JG; Register RB; Sardana MK; Shearman MS; Smith AL; Shi XP; Yin KC; Shafer JA; Gardell SJ
    Nature; 2000 Jun; 405(6787):689-94. PubMed ID: 10864326
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Partial loss of presenilins causes seborrheic keratosis and autoimmune disease in mice.
    Tournoy J; Bossuyt X; Snellinx A; Regent M; Garmyn M; Serneels L; Saftig P; Craessaerts K; De Strooper B; Hartmann D
    Hum Mol Genet; 2004 Jul; 13(13):1321-31. PubMed ID: 15128703
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Down-regulation amyloid beta-protein 42 production by interfering with transcript of presenilin 1 gene with siRNA.
    Luo HM; Deng H; Xiao F; Gao Q; Weng W; Zhang PF; Li XG
    Acta Pharmacol Sin; 2004 Dec; 25(12):1613-8. PubMed ID: 15569405
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Molecular dissection of domains in mutant presenilin 2 that mediate overproduction of amyloidogenic forms of amyloid beta peptides. Inability of truncated forms of PS2 with familial Alzheimer's disease mutation to increase secretion of Abeta42.
    Tomita T; Tokuhiro S; Hashimoto T; Aiba K; Saido TC; Maruyama K; Iwatsubo T
    J Biol Chem; 1998 Aug; 273(33):21153-60. PubMed ID: 9694871
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Aspartate mutations in presenilin and gamma-secretase inhibitors both impair notch1 proteolysis and nuclear translocation with relative preservation of notch1 signaling.
    Berezovska O; Jack C; McLean P; Aster JC; Hicks C; Xia W; Wolfe MS; Kimberly WT; Weinmaster G; Selkoe DJ; Hyman BT
    J Neurochem; 2000 Aug; 75(2):583-93. PubMed ID: 10899933
    [TBL] [Abstract][Full Text] [Related]  

  • 39. [Study on expression of PS1 in APP-PS1 double gene stably transfected cell lines and its relation to gamma-secretase].
    Liang P; Pan YX; Zhao XM; Du HZ; Zhang JM
    Zhonghua Bing Li Xue Za Zhi; 2005 May; 34(5):297-301. PubMed ID: 16181553
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Enhanced generation of intracellular Abeta42 amyloid peptide by mutation of presenilins PS1 and PS2.
    Takeda K; Araki W; Tabira T
    Eur J Neurosci; 2004 Jan; 19(2):258-264. PubMed ID: 14725619
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.