122 related articles for article (PubMed ID: 9224813)
21. The effect of purine phosphonomethoxyalkyl derivatives on DNA synthesis in CHO Chinese hamster cells.
Stĕtina R; Votruba I; Holý A; Merta A
Neoplasma; 1993; 40(6):373-8. PubMed ID: 8289970
[TBL] [Abstract][Full Text] [Related]
22. Tenofovir diphosphate is a poor substrate and a weak inhibitor of rat DNA polymerases alpha, delta, and epsilon*.
Birkus G; Hájek M; Kramata P; Votruba I; Holý A; Otová B
Antimicrob Agents Chemother; 2002 May; 46(5):1610-3. PubMed ID: 11959615
[TBL] [Abstract][Full Text] [Related]
23. Potent inhibition of human immunodeficiency virus and herpes simplex virus type 1 by 9-(2-phosphonylmethoxyethyl)adenine in primary macrophages is determined by drug metabolism, nucleotide pools, and cytokines.
Perno CF; Balestra E; Aquaro S; Panti S; Cenci A; Lazzarino G; Tavazzi B; Di Pierro D; Balzarini J; Calio R
Mol Pharmacol; 1996 Aug; 50(2):359-66. PubMed ID: 8700144
[TBL] [Abstract][Full Text] [Related]
24. [Acyclic nucleoside phosphonates as potential antineoplastic agents].
Votruba I; Otová B; Holý A
Cas Lek Cesk; 2008; 147(9):471-7. PubMed ID: 18988489
[TBL] [Abstract][Full Text] [Related]
25. Point mutations in human guanylate kinase account for acquired resistance to anticancer nucleotide analogue PMEG.
Mertlíková-Kaiserová H; Rumlová M; Tloušťová E; Procházková E; Holý A; Votruba I
Biochem Pharmacol; 2011 Jul; 82(2):131-8. PubMed ID: 21515241
[TBL] [Abstract][Full Text] [Related]
26. Susceptibilities of zidovudine-resistant variants of human immunodeficiency virus type 1 to inhibition by acyclic nucleoside phosphonates.
Gong YF; Marshall DR; Srinivas RV; Fridland A
Antimicrob Agents Chemother; 1994 Jul; 38(7):1683-7. PubMed ID: 7979311
[TBL] [Abstract][Full Text] [Related]
27. Anti-human immunodeficiency virus activity and cellular metabolism of a potential prodrug of the acyclic nucleoside phosphonate 9-R-(2-phosphonomethoxypropyl)adenine (PMPA), Bis(isopropyloxymethylcarbonyl)PMPA.
Robbins BL; Srinivas RV; Kim C; Bischofberger N; Fridland A
Antimicrob Agents Chemother; 1998 Mar; 42(3):612-7. PubMed ID: 9517941
[TBL] [Abstract][Full Text] [Related]
28. Activity of the (R)-enantiomers of 9-(2-phosphonylmethoxypropyl)-adenine and 9-(2-phosphonylmethoxypropyl)-2,6-diaminopurine against human immunodeficiency virus in different human cell systems.
Balzarini J; Aquaro S; Perno CF; Witvrouw M; Holý A; De Clercq E
Biochem Biophys Res Commun; 1996 Feb; 219(2):337-41. PubMed ID: 8604988
[TBL] [Abstract][Full Text] [Related]
29. Mechanism of inhibition of adenovirus DNA replication by the acyclic nucleoside triphosphate analogue (S)-HPMPApp: influence of the adenovirus DNA binding protein.
Mul YM; van Miltenburg RT; De Clercq E; van der Vliet PC
Nucleic Acids Res; 1989 Nov; 17(22):8917-29. PubMed ID: 2587248
[TBL] [Abstract][Full Text] [Related]
30. Involvement of MAP kinases in the cytotoxicity of acyclic nucleoside phosphonates.
Mertlíková-Kaiserová H; Nejedlá M; Holy A; Votruba I
Anticancer Res; 2012 Feb; 32(2):497-501. PubMed ID: 22287737
[TBL] [Abstract][Full Text] [Related]
31. 9-(2-Phosphonylmethoxyethyl)adenine induces tumor cell differentiation or cell death by blocking cell cycle progression through the S phase.
Hatse S; Schols D; De Clercq E; Balzarini J
Cell Growth Differ; 1999 Jun; 10(6):435-46. PubMed ID: 10392905
[TBL] [Abstract][Full Text] [Related]
32. Metabolic pathways for activation of the antiviral agent 9-(2-phosphonylmethoxyethyl)adenine in human lymphoid cells.
Robbins BL; Greenhaw J; Connelly MC; Fridland A
Antimicrob Agents Chemother; 1995 Oct; 39(10):2304-8. PubMed ID: 8619586
[TBL] [Abstract][Full Text] [Related]
33. Interaction of guanine phosphonomethoxyalkyl derivatives with GMP kinase isoenzymes.
Krejcová R; Horská K; Votruba I; Holý A
Biochem Pharmacol; 2000 Dec; 60(12):1907-13. PubMed ID: 11108807
[TBL] [Abstract][Full Text] [Related]
34. Biochemical pharmacology of acyclic nucleotide analogues.
Bronson JJ; Ho HT; De Boeck H; Woods K; Ghazzouli I; Martin JC; Hitchcock MJ
Ann N Y Acad Sci; 1990; 616():398-407. PubMed ID: 2078030
[TBL] [Abstract][Full Text] [Related]
35. Acyclic nucleotide analogues suppress growth and induce apoptosis in human leukemia cell lines.
Franek F; Holy A; Votruba I; Eckschlager T
Int J Oncol; 1999 Apr; 14(4):745-52. PubMed ID: 10087324
[TBL] [Abstract][Full Text] [Related]
36. Cellular metabolism and enzymatic phosphorylation of 9-(2-phosphonylmethoxyethyl) guanine (PMEG), a potent antiviral agent.
Ho HT; Woods KL; Konrad SA; De Boeck H; Hitchcock MJ
Adv Exp Med Biol; 1992; 312():159-66. PubMed ID: 1514440
[No Abstract] [Full Text] [Related]
37. Herpes simplex virus-specified DNA polymerase is the target for the antiviral action of 9-(2-phosphonylmethoxyethyl)adenine.
Foster SA; Cerny J; Cheng YC
J Biol Chem; 1991 Jan; 266(1):238-44. PubMed ID: 1845964
[TBL] [Abstract][Full Text] [Related]
38. Antiproliferative effects of acyclic nucleoside phosphonates on human papillomavirus (HPV)-harboring cell lines compared with HPV-negative cell lines.
Andrei G; Snoeck R; Piette J; Delvenne P; De Clercq E
Oncol Res; 1998; 10(10):523-31. PubMed ID: 10338155
[TBL] [Abstract][Full Text] [Related]
39. Cytostatic activity of antiviral acyclic nucleoside phosphonates in rodent lymphocytes.
Zídek Z; Potmesil P; Holý A
Toxicol Appl Pharmacol; 2003 Nov; 192(3):246-53. PubMed ID: 14575642
[TBL] [Abstract][Full Text] [Related]
40. Different inhibitory potencies of acyclic phosphonomethoxyalkyl nucleotide analogs toward DNA polymerases alpha, delta and epsilon.
Kramata P; Votruba I; Otová B; Holý A
Mol Pharmacol; 1996 Jun; 49(6):1005-11. PubMed ID: 8649338
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
