These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

132 related articles for article (PubMed ID: 9240358)

  • 1. Novel non-nucleoside inhibitors of human immunodeficiency virus type 1 reverse transcriptase. 6. 2-Indol-3-yl- and 2-azaindol-3-yl-dipyridodiazepinones.
    Kelly TA; McNeil DW; Rose JM; David E; Shih CK; Grob PM
    J Med Chem; 1997 Jul; 40(15):2430-3. PubMed ID: 9240358
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel nonnucleoside inhibitors of HIV-1 reverse transcriptase. 7. 8-Arylethyldipyridodiazepinones as potent broad-spectrum inhibitors of wild-type and mutant enzymes.
    Klunder JM; Hoermann M; Cywin CL; David E; Brickwood JR; Schwartz R; Barringer KJ; Pauletti D; Shih CK; Erickson DA; Sorge CL; Joseph DP; Hattox SE; Adams J; Grob PM
    J Med Chem; 1998 Jul; 41(16):2960-71. PubMed ID: 9685235
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Non-nucleoside HIV-1 reverse transcriptase inhibitors. Part 11: structural modulations of diaryltriazines with potent anti-HIV activity.
    Xiong YZ; Chen FE; Balzarini J; De Clercq E; Pannecouque C
    Eur J Med Chem; 2008 Jun; 43(6):1230-6. PubMed ID: 17869386
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and studies of new 2-(coumarin-4-yloxy)-4,6-(substituted)-S-triazine derivatives as potential anti-HIV agents.
    Mahajan DH; Pannecouque C; De Clercq E; Chikhalia KH
    Arch Pharm (Weinheim); 2009 May; 342(5):281-90. PubMed ID: 19415671
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Novel nonnucleoside inhibitors of HIV-1 reverse transcriptase. 8. 8-Aryloxymethyl- and 8-arylthiomethyldipyridodiazepinones.
    Cywin CL; Klunder JM; Hoermann M; Brickwood JR; David E; Grob PM; Schwartz R; Pauletti D; Barringer KJ; Shih CK; Sorge CL; Erickson DA; Joseph DP; Hattox SE
    J Med Chem; 1998 Jul; 41(16):2972-84. PubMed ID: 9685236
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural insights into mechanisms of non-nucleoside drug resistance for HIV-1 reverse transcriptases mutated at codons 101 or 138.
    Ren J; Nichols CE; Stamp A; Chamberlain PP; Ferris R; Weaver KL; Short SA; Stammers DK
    FEBS J; 2006 Aug; 273(16):3850-60. PubMed ID: 16911530
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and evaluation of N-aryl pyrrolidinones as novel anti-HIV-1 agents. Part 1.
    Wu B; Kuhen K; Ngoc Nguyen T; Ellis D; Anaclerio B; He X; Yang K; Karanewsky D; Yin H; Wolff K; Bieza K; Caldwell J; He Y
    Bioorg Med Chem Lett; 2006 Jul; 16(13):3430-3. PubMed ID: 16632349
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Non-nucleoside HIV-1 reverse transcriptase inhibitors di-halo-indolyl aryl sulfones achieve tight binding to drug-resistant mutants by targeting the enzyme-substrate complex.
    Samuele A; Kataropoulou A; Viola M; Zanoli S; La Regina G; Piscitelli F; Silvestri R; Maga G
    Antiviral Res; 2009 Jan; 81(1):47-55. PubMed ID: 18984007
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Non-nucleoside HIV-1 reverse transcriptase inhibitors. Part 13: synthesis of fluorine-containing diaryltriazine derivatives for in vitro anti-HIV evaluation against wild-type strain.
    Xiong YZ; Chen FE; Balzarini J; De Clercq E; Pannecouque C
    Chem Biodivers; 2009 Apr; 6(4):561-8. PubMed ID: 19353537
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Scaffold hopping in the rational design of novel HIV-1 non-nucleoside reverse transcriptase inhibitors.
    O'Meara JA; Jakalian A; LaPlante S; Bonneau PR; Coulombe R; Faucher AM; Guse I; Landry S; Racine J; Simoneau B; Thavonekham B; Yoakim C
    Bioorg Med Chem Lett; 2007 Jun; 17(12):3362-6. PubMed ID: 17451954
    [TBL] [Abstract][Full Text] [Related]  

  • 11. New anti-HIV agents and targets.
    De Clercq E
    Med Res Rev; 2002 Nov; 22(6):531-65. PubMed ID: 12369088
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pyrazole NNRTIs 1: design and initial optimisation of a novel template.
    Mowbray CE; Burt C; Corbau R; Perros M; Tran I; Stupple PA; Webster R; Wood A
    Bioorg Med Chem Lett; 2009 Oct; 19(19):5599-602. PubMed ID: 19709880
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effect of a bound non-nucleoside RT inhibitor on the dynamics of wild-type and mutant HIV-1 reverse transcriptase.
    Zhou Z; Madrid M; Evanseck JD; Madura JD
    J Am Chem Soc; 2005 Dec; 127(49):17253-60. PubMed ID: 16332074
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Slow-, tight-binding HIV-1 reverse transcriptase non-nucleoside inhibitors highly active against drug-resistant mutants.
    Cancio R; Mai A; Rotili D; Artico M; Sbardella G; Clotet-Codina I; Esté JA; Crespan E; Zanoli S; Hübscher U; Spadari S; Maga G
    ChemMedChem; 2007 Apr; 2(4):445-8. PubMed ID: 17323401
    [No Abstract]   [Full Text] [Related]  

  • 15. Dihydro(alkylthio)(naphthylmethyl)oxopyrimidines: novel non-nucleoside reverse transcriptase inhibitors of the S-DABO series.
    Mai A; Artico M; Sbardella G; Quartarone S; Massa S; Loi AG; De Montis A; Scintu F; Putzolu M; La Colla P
    J Med Chem; 1997 May; 40(10):1447-54. PubMed ID: 9154967
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [d4U]-butyne-[HI-236] as a non-cleavable, bifunctional NRTI/NNRTI HIV-1 reverse-transcriptase inhibitor.
    Hunter R; Muhanji CI; Hale I; Bailey CM; Basavapathruni A; Anderson KS
    Bioorg Med Chem Lett; 2007 May; 17(9):2614-7. PubMed ID: 17317163
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mutational analysis of trp-229 of human immunodeficiency virus type 1 reverse transcriptase (RT) identifies this amino acid residue as a prime target for the rational design of new non-nucleoside RT inhibitors.
    Pelemans H; Esnouf R; De Clercq E; Balzarini J
    Mol Pharmacol; 2000 May; 57(5):954-60. PubMed ID: 10779379
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Docking of non-nucleoside inhibitors: neotripterifordin and its derivatives to HIV-1 reverse transcriptase.
    Zhou Z; Madrid M; Madura JD
    Proteins; 2002 Dec; 49(4):529-42. PubMed ID: 12402361
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and anti-HIV activity of [d4U]-[trovirdine analogue] and [d4T]-[trovirdine analogue] heterodimers as inhibitors of HIV-1 reverse transcriptase.
    Gavriliu D; Fossey C; Ciurea A; Delbederi Z; Sugeac E; Ladurée D; Schmidt S; Laumond G; Aubertin AM
    Nucleosides Nucleotides Nucleic Acids; 2002; 21(8-9):505-33. PubMed ID: 12484448
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and biological evaluation of novel C5 halogen-functionalized S-DABO as potent HIV-1 non-nucleoside reverse transcriptase inhibitors.
    Qin H; Liu C; Guo Y; Wang R; Zhang J; Ma L; Zhang Z; Wang X; Cui Y; Liu J
    Bioorg Med Chem; 2010 May; 18(9):3231-7. PubMed ID: 20371182
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.