187 related articles for article (PubMed ID: 9247124)
1. The interaction of Ras with GTPase-activating proteins.
Wittinghofer A; Scheffzek K; Ahmadian MR
FEBS Lett; 1997 Jun; 410(1):63-7. PubMed ID: 9247124
[TBL] [Abstract][Full Text] [Related]
2. The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants.
Scheffzek K; Ahmadian MR; Kabsch W; Wiesmüller L; Lautwein A; Schmitz F; Wittinghofer A
Science; 1997 Jul; 277(5324):333-8. PubMed ID: 9219684
[TBL] [Abstract][Full Text] [Related]
3. Crystal structure of the GTPase-activating domain of human p120GAP and implications for the interaction with Ras.
Scheffzek K; Lautwein A; Kabsch W; Ahmadian MR; Wittinghofer A
Nature; 1996 Dec; 384(6609):591-6. PubMed ID: 8955277
[TBL] [Abstract][Full Text] [Related]
4. G proteins, effectors and GAPs: structure and mechanism.
Sprang SR
Curr Opin Struct Biol; 1997 Dec; 7(6):849-56. PubMed ID: 9434906
[TBL] [Abstract][Full Text] [Related]
5. Signal transduction via Ras.
Wittinghofer A
Biol Chem; 1998; 379(8-9):933-7. PubMed ID: 9792425
[TBL] [Abstract][Full Text] [Related]
6. GTP hydrolysis mechanisms in ras p21 and in the ras-GAP complex studied by fluorescence measurements on tryptophan mutants.
Antonny B; Chardin P; Roux M; Chabre M
Biochemistry; 1991 Aug; 30(34):8287-95. PubMed ID: 1883817
[TBL] [Abstract][Full Text] [Related]
7. Linear free energy relationships in the intrinsic and GTPase activating protein-stimulated guanosine 5'-triphosphate hydrolysis of p21ras.
Schweins T; Geyer M; Kalbitzer HR; Wittinghofer A; Warshel A
Biochemistry; 1996 Nov; 35(45):14225-31. PubMed ID: 8916907
[TBL] [Abstract][Full Text] [Related]
8. Formation of a transition-state analog of the Ras GTPase reaction by Ras-GDP, tetrafluoroaluminate, and GTPase-activating proteins.
Mittal R; Ahmadian MR; Goody RS; Wittinghofer A
Science; 1996 Jul; 273(5271):115-7. PubMed ID: 8658179
[TBL] [Abstract][Full Text] [Related]
9. The GAP arginine finger movement into the catalytic site of Ras increases the activation entropy.
Kötting C; Kallenbach A; Suveyzdis Y; Wittinghofer A; Gerwert K
Proc Natl Acad Sci U S A; 2008 Apr; 105(17):6260-5. PubMed ID: 18434546
[TBL] [Abstract][Full Text] [Related]
10. GAP into the breach.
Sprang SR
Science; 1997 Jul; 277(5324):329-30. PubMed ID: 9518363
[No Abstract] [Full Text] [Related]
11. Confirmation of the arginine-finger hypothesis for the GAP-stimulated GTP-hydrolysis reaction of Ras.
Ahmadian MR; Stege P; Scheffzek K; Wittinghofer A
Nat Struct Biol; 1997 Sep; 4(9):686-9. PubMed ID: 9302992
[TBL] [Abstract][Full Text] [Related]
12. A phosphoryl transfer intermediate in the GTPase reaction of Ras in complex with its GTPase-activating protein.
Kötting C; Blessenohl M; Suveyzdis Y; Goody RS; Wittinghofer A; Gerwert K
Proc Natl Acad Sci U S A; 2006 Sep; 103(38):13911-6. PubMed ID: 16968776
[TBL] [Abstract][Full Text] [Related]
13. Transition state structures and the roles of catalytic residues in GAP-facilitated GTPase of Ras as elucidated by (18)O kinetic isotope effects.
Du X; Sprang SR
Biochemistry; 2009 Jun; 48(21):4538-47. PubMed ID: 19610677
[TBL] [Abstract][Full Text] [Related]
14. Ras-GTPase activating protein (GAP): a putative effector for Ras.
Tocque B; Delumeau I; Parker F; Maurier F; Multon MC; Schweighoffer F
Cell Signal; 1997 Feb; 9(2):153-8. PubMed ID: 9113414
[TBL] [Abstract][Full Text] [Related]
15. Structures of Cdc42 bound to the active and catalytically compromised forms of Cdc42GAP.
Nassar N; Hoffman GR; Manor D; Clardy JC; Cerione RA
Nat Struct Biol; 1998 Dec; 5(12):1047-52. PubMed ID: 9846874
[TBL] [Abstract][Full Text] [Related]
16. Individual rate constants for the interaction of Ras proteins with GTPase-activating proteins determined by fluorescence spectroscopy.
Ahmadian MR; Hoffmann U; Goody RS; Wittinghofer A
Biochemistry; 1997 Apr; 36(15):4535-41. PubMed ID: 9109662
[TBL] [Abstract][Full Text] [Related]
17. Ras and GTPase-activating protein (GAP) drive GTP into a precatalytic state as revealed by combining FTIR and biomolecular simulations.
Rudack T; Xia F; Schlitter J; Kötting C; Gerwert K
Proc Natl Acad Sci U S A; 2012 Sep; 109(38):15295-300. PubMed ID: 22949691
[TBL] [Abstract][Full Text] [Related]
18. Computational characterization of the chemical step in the GTP hydrolysis by Ras-GAP for the wild-type and G13V mutated Ras.
Mironov VA; Khrenova MG; Lychko LA; Nemukhin AV
Proteins; 2015 Jun; 83(6):1046-53. PubMed ID: 25820867
[TBL] [Abstract][Full Text] [Related]
19. Investigation of the GTP-binding/GTPase cycle of Cdc42Hs using extrinsic reporter group fluorescence.
Nomanbhoy TK; Leonard DA; Manor D; Cerione RA
Biochemistry; 1996 Apr; 35(14):4602-8. PubMed ID: 8605211
[TBL] [Abstract][Full Text] [Related]
20. Real-time in vitro measurement of intrinsic and Ras GAP-mediated GTP hydrolysis.
Shutes A; Der CJ
Methods Enzymol; 2006; 407():9-22. PubMed ID: 16757310
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]