319 related articles for article (PubMed ID: 9264539)
1. Synthesis and kinetic studies of diphenyl 1-(N-peptidylamino)alkanephosphonate esters and their biotinylated derivatives as inhibitors of serine proteases and probes for lymphocyte granzymes.
Abuelyaman AS; Jackson DS; Hudig D; Woodard SL; Powers JC
Arch Biochem Biophys; 1997 Aug; 344(2):271-80. PubMed ID: 9264539
[TBL] [Abstract][Full Text] [Related]
2. Fluorescent derivatives of diphenyl [1-(N-peptidylamino)alkyl]phosphonate esters: synthesis and use in the inhibition and cellular localization of serine proteases.
Abuelyaman AS; Hudig D; Woodard SL; Powers JC
Bioconjug Chem; 1994; 5(5):400-5. PubMed ID: 7849068
[TBL] [Abstract][Full Text] [Related]
3. Chymase-directed serine protease inhibitor that reacts with a single 30-kDa granzyme and blocks NK-mediated cytotoxicity.
Woodard SL; Jackson DS; Abuelyaman AS; Powers JC; Winkler U; Hudig D
J Immunol; 1994 Dec; 153(11):5016-25. PubMed ID: 7963562
[TBL] [Abstract][Full Text] [Related]
4. Purification and characterization of lymphocyte chymase I, a granzyme implicated in perforin-mediated lysis.
Woodard SL; Fraser SA; Winkler U; Jackson DS; Kam CM; Powers JC; Hudig D
J Immunol; 1998 May; 160(10):4988-93. PubMed ID: 9590247
[TBL] [Abstract][Full Text] [Related]
5. Irreversible inhibition of serine proteases by peptide derivatives of (alpha-aminoalkyl)phosphonate diphenyl esters.
Oleksyszyn J; Powers JC
Biochemistry; 1991 Jan; 30(2):485-93. PubMed ID: 1988040
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and evaluation of diphenyl phosphonate esters as inhibitors of the trypsin-like granzymes A and K and mast cell tryptase.
Jackson DS; Fraser SA; Ni LM; Kam CM; Winkler U; Johnson DA; Froelich CJ; Hudig D; Powers JC
J Med Chem; 1998 Jun; 41(13):2289-301. PubMed ID: 9632362
[TBL] [Abstract][Full Text] [Related]
7. Granzymes (lymphocyte serine proteases): characterization with natural and synthetic substrates and inhibitors.
Kam CM; Hudig D; Powers JC
Biochim Biophys Acta; 2000 Mar; 1477(1-2):307-23. PubMed ID: 10708866
[TBL] [Abstract][Full Text] [Related]
8. Sulfonyl fluoride serine protease inhibitors inactivate RNK-16 lymphocyte granule proteases and reduce lysis by granule extracts and perforin.
Ewoldt GR; Winkler U; Powers JC; Hudig D
Mol Immunol; 1992 Jun; 29(6):713-21. PubMed ID: 1603092
[TBL] [Abstract][Full Text] [Related]
9. Selective chemical functional probes of granzymes A and B reveal granzyme B is a major effector of natural killer cell-mediated lysis of target cells.
Mahrus S; Craik CS
Chem Biol; 2005 May; 12(5):567-77. PubMed ID: 15911377
[TBL] [Abstract][Full Text] [Related]
10. The function of lymphocyte proteases. Inhibition and restoration of granule-mediated lysis with isocoumarin serine protease inhibitors.
Hudig D; Allison NJ; Pickett TM; Winkler U; Kam CM; Powers JC
J Immunol; 1991 Aug; 147(4):1360-8. PubMed ID: 1869829
[TBL] [Abstract][Full Text] [Related]
11. Human granzyme B is essential for DNA fragmentation of susceptible target cells.
Su B; Bochan MR; Hanna WL; Froelich CJ; Brahmi Z
Eur J Immunol; 1994 Sep; 24(9):2073-80. PubMed ID: 8088328
[TBL] [Abstract][Full Text] [Related]
12. A novel substrate-binding pocket interaction restricts the specificity of the human NK cell-specific serine protease, Met-ase-1.
Smyth MJ; O'Connor MD; Trapani JA; Kershaw MH; Brinkworth RI
J Immunol; 1996 Jun; 156(11):4174-81. PubMed ID: 8666785
[TBL] [Abstract][Full Text] [Related]
13. The human cytotoxic T cell granule serine protease granzyme H has chymotrypsin-like (chymase) activity and is taken up into cytoplasmic vesicles reminiscent of granzyme B-containing endosomes.
Edwards KM; Kam CM; Powers JC; Trapani JA
J Biol Chem; 1999 Oct; 274(43):30468-73. PubMed ID: 10521426
[TBL] [Abstract][Full Text] [Related]
14. Characterization, application and potential uses of biotin-tagged inhibitors for lymphocyte serine proteases (granzymes).
Winkler U; Allison NJ; Woodard SL; Gault RA; Ewoldt GR; Kam CM; Abuelyaman A; Powers JC; Hudig D
Mol Immunol; 1996; 33(7-8):615-23. PubMed ID: 8760273
[TBL] [Abstract][Full Text] [Related]
15. Human and murine cytotoxic T lymphocyte serine proteases: subsite mapping with peptide thioester substrates and inhibition of enzyme activity and cytolysis by isocoumarins.
Odake S; Kam CM; Narasimhan L; Poe M; Blake JT; Krahenbuhl O; Tschopp J; Powers JC
Biochemistry; 1991 Feb; 30(8):2217-27. PubMed ID: 1998680
[TBL] [Abstract][Full Text] [Related]
16. Synergistic inhibition of human cell-mediated cytotoxicity by complement component antisera indicates that target cell lysis may result from an enzymatic cascade involving granzymes and perforin.
Brahmi Z; Csipo I; Bochan MR; Su B; Montel AH; Morse PA
Nat Immun; 1995 Sep; 14(5-6):271-85. PubMed ID: 8933821
[TBL] [Abstract][Full Text] [Related]
17. Generation of antigenic peptides by lymphocyte granule serine proteases (granzymes).
Carter CR; Sayers TJ; Wiltrout RH; Turcovski-Corrales SM; Taub DD
Cell Immunol; 1996 Sep; 172(2):235-45. PubMed ID: 8964086
[TBL] [Abstract][Full Text] [Related]
18. Asymmetric preference of serine proteases toward phosphonate and phosphinate esters.
Walker B; Wharry S; Hamilton RJ; Martin SL; Healy A; Walker BJ
Biochem Biophys Res Commun; 2000 Oct; 276(3):1235-9. PubMed ID: 11027616
[TBL] [Abstract][Full Text] [Related]
19. Irreversible inhibition of serine proteases by peptidyl derivatives of alpha-aminoalkylphosphonate diphenyl esters.
Oleksyszyn J; Powers JC
Biochem Biophys Res Commun; 1989 May; 161(1):143-9. PubMed ID: 2730652
[TBL] [Abstract][Full Text] [Related]
20. The 2.2 A crystal structure of human chymase in complex with succinyl-Ala-Ala-Pro-Phe-chloromethylketone: structural explanation for its dipeptidyl carboxypeptidase specificity.
Pereira PJ; Wang ZM; Rubin H; Huber R; Bode W; Schechter NM; Strobl S
J Mol Biol; 1999 Feb; 286(1):163-73. PubMed ID: 9931257
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]