BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

294 related articles for article (PubMed ID: 9271331)

  • 1. Mutant acetylcholinesterases as potential detoxification agents for organophosphate poisoning.
    Saxena A; Maxwell DM; Quinn DM; Radić Z; Taylor P; Doctor BP
    Biochem Pharmacol; 1997 Jul; 54(2):269-74. PubMed ID: 9271331
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Amplification of the effectiveness of acetylcholinesterase for detoxification of organophosphorus compounds by bis-quaternary oximes.
    Caranto GR; Waibel KH; Asher JM; Larrison RW; Brecht KM; Schutz MB; Raveh L; Ashani Y; Wolfe AD; Maxwell DM
    Biochem Pharmacol; 1994 Jan; 47(2):347-57. PubMed ID: 8304979
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Aging-resistant organophosphate bioscavenger based on polyethylene glycol-conjugated F338A human acetylcholinesterase.
    Mazor O; Cohen O; Kronman C; Raveh L; Stein D; Ordentlich A; Shafferman A
    Mol Pharmacol; 2008 Sep; 74(3):755-63. PubMed ID: 18523134
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Evaluation of several oximes as reactivators of unaged soman-inhibited whole blood acetylcholinesterase in rabbits.
    Harris LW; Anderson DR; Lennox WJ; Woodard CL; Pastelak AM; Vanderpool BA
    Biochem Pharmacol; 1990 Dec; 40(12):2677-82. PubMed ID: 2260991
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Two possible orientations of the HI-6 molecule in the reactivation of organophosphate-inhibited acetylcholinesterase.
    Luo C; Leader H; Radic Z; Maxwell DM; Taylor P; Doctor BP; Saxena A
    Biochem Pharmacol; 2003 Aug; 66(3):387-92. PubMed ID: 12907237
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A common mechanism for resistance to oxime reactivation of acetylcholinesterase inhibited by organophosphorus compounds.
    Maxwell DM; Brecht KM; Sweeney RE
    Chem Biol Interact; 2013 Mar; 203(1):72-6. PubMed ID: 22982773
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The role of glutamate-199 in the aging of cholinesterase.
    Saxena A; Doctor BP; Maxwell DM; Lenz DE; Radic Z; Taylor P
    Biochem Biophys Res Commun; 1993 Nov; 197(1):343-9. PubMed ID: 7902714
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Phosphoryl oxime inhibition of acetylcholinesterase during oxime reactivation is prevented by edrophonium.
    Luo C; Saxena A; Smith M; Garcia G; Radić Z; Taylor P; Doctor BP
    Biochemistry; 1999 Aug; 38(31):9937-47. PubMed ID: 10433700
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Amidine-oximes: reactivators for organophosphate exposure.
    Kalisiak J; Ralph EC; Zhang J; Cashman JR
    J Med Chem; 2011 May; 54(9):3319-30. PubMed ID: 21438612
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Catalytic Soman Scavenging by the Y337A/F338A Acetylcholinesterase Mutant Assisted with Novel Site-Directed Aldoximes.
    Kovarik Z; Maček Hrvat N; Katalinić M; Sit RK; Paradyse A; Žunec S; Musilek K; Fokin VV; Taylor P; Radić Z
    Chem Res Toxicol; 2015 May; 28(5):1036-44. PubMed ID: 25835984
    [TBL] [Abstract][Full Text] [Related]  

  • 11. In vitro and in vivo evaluation of pyridinium oximes: mode of interaction with acetylcholinesterase, effect on tabun- and soman-poisoned mice and their cytotoxicity.
    Calić M; Vrdoljak AL; Radić B; Jelić D; Jun D; Kuca K; Kovarik Z
    Toxicology; 2006 Feb; 219(1-3):85-96. PubMed ID: 16332406
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Probing the role of amino acids in oxime-mediated reactivation of nerve agent-inhibited human acetylcholinesterase.
    Chambers C; Luo C; Tong M; Yang Y; Saxena A
    Toxicol In Vitro; 2015 Mar; 29(2):408-14. PubMed ID: 25451328
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Acceleration of oxime-induced reactivation of organophosphate-inhibited fetal bovine serum acetylcholinesterase by monoquaternary and bisquaternary ligands.
    Luo C; Ashani Y; Doctor BP
    Mol Pharmacol; 1998 Apr; 53(4):718-26. PubMed ID: 9547363
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The oximes HI-6 and MMB-4 fail to reactivate soman-inhibited human and guinea pig AChE: A kinetic in vitro study.
    Worek F; Thiermann H; Wille T
    Toxicol Lett; 2018 Sep; 293():216-221. PubMed ID: 28993240
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Suitability of human butyrylcholinesterase as therapeutic marker and pseudo catalytic scavenger in organophosphate poisoning: a kinetic analysis.
    Aurbek N; Thiermann H; Eyer F; Eyer P; Worek F
    Toxicology; 2009 May; 259(3):133-9. PubMed ID: 19428953
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interactions between acetylcholinesterase, toxic organophosphorus compounds and a short series of structurally related non-oxime reactivators: Analysis of reactivation and inhibition kinetics in vitro.
    Horn G; de Koning MC; van Grol M; Thiermann H; Worek F
    Toxicol Lett; 2018 Dec; 299():218-225. PubMed ID: 30312685
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Amino acid residues controlling reactivation of organophosphonyl conjugates of acetylcholinesterase by mono- and bisquaternary oximes.
    Ashani Y; Radić Z; Tsigelny I; Vellom DC; Pickering NA; Quinn DM; Doctor BP; Taylor P
    J Biol Chem; 1995 Mar; 270(11):6370-80. PubMed ID: 7890775
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Kinetic analysis of interactions of different sarin and tabun analogues with human acetylcholinesterase and oximes: is there a structure-activity relationship?
    Aurbek N; Herkert NM; Koller M; Thiermann H; Worek F
    Chem Biol Interact; 2010 Sep; 187(1-3):215-9. PubMed ID: 20105433
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Interaction of pentylsarin analogues with human acetylcholinesterase: a kinetic study.
    Worek F; Herkert NM; Koller M; Aurbek N; Thiermann H
    Toxicol Lett; 2009 Jun; 187(2):119-23. PubMed ID: 19429253
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Reactivation of organophosphate-inhibited human AChE by combinations of obidoxime and HI 6 in vitro.
    Worek F; Aurbek N; Thiermann H
    J Appl Toxicol; 2007; 27(6):582-8. PubMed ID: 17370251
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.