149 related articles for article (PubMed ID: 9274003)
1. Sulfone derivatives with anti-HIV activity.
Silvestri R; Artico M; Massa S; Stefancich G; Congeddu E; Putzolu M; La Colla P
Farmaco; 1997 May; 52(5):323-9. PubMed ID: 9274003
[TBL] [Abstract][Full Text] [Related]
2. Novel indolyl aryl sulfones active against HIV-1 carrying NNRTI resistance mutations: synthesis and SAR studies.
Silvestri R; De Martino G; La Regina G; Artico M; Massa S; Vargiu L; Mura M; Loi AG; Marceddu T; La Colla P
J Med Chem; 2003 Jun; 46(12):2482-93. PubMed ID: 12773052
[TBL] [Abstract][Full Text] [Related]
3. 2H-Pyrrolo[3,4-b] [1,5]benzothiazepine derivatives as potential inhibitors of HIV-1 reverse transcriptase.
Di Santo R; Costi R
Farmaco; 2005 May; 60(5):385-92. PubMed ID: 15910811
[TBL] [Abstract][Full Text] [Related]
4. Design, molecular modeling, synthesis, and anti-HIV-1 activity of new indolyl aryl sulfones. Novel derivatives of the indole-2-carboxamide.
Ragno R; Coluccia A; La Regina G; De Martino G; Piscitelli F; Lavecchia A; Novellino E; Bergamini A; Ciaprini C; Sinistro A; Maga G; Crespan E; Artico M; Silvestri R
J Med Chem; 2006 Jun; 49(11):3172-84. PubMed ID: 16722636
[TBL] [Abstract][Full Text] [Related]
5. Anti-HIV-1 activity of pyrryl aryl sulfone (PAS) derivatives: synthesis and SAR studies of novel esters and amides at the position 2 of the pyrrole nucleus.
Silvestri R; Artico M; La Regina G; De Martino G; La Colla M; Loddo R; La Colla P
Farmaco; 2004 Mar; 59(3):201-10. PubMed ID: 14987983
[TBL] [Abstract][Full Text] [Related]
6. Synthesis of pyrryl aryl sulfones targeted at the HIV-1 reverse transcriptase.
Artico M; Silvestri R; Stefancich G; Massa S; Pagnozzi E; Musu D; Scintu F; Pinna E; Tinti E; La Colla P
Arch Pharm (Weinheim); 1995 Mar; 328(3):223-9. PubMed ID: 7539250
[TBL] [Abstract][Full Text] [Related]
7. Design, synthesis, biological evaluation, and molecular modeling studies of TIBO-like cyclic sulfones as non-nucleoside HIV-1 reverse transcriptase inhibitors.
Di Santo R; Costi R; Artico M; Ragno R; Lavecchia A; Novellino E; Gavuzzo E; La Torre F; Cirilli R; Cancio R; Maga G
ChemMedChem; 2006 Jan; 1(1):82-95. PubMed ID: 16892340
[TBL] [Abstract][Full Text] [Related]
8. Non-nucleoside HIV-1 reverse transcriptase inhibitors di-halo-indolyl aryl sulfones achieve tight binding to drug-resistant mutants by targeting the enzyme-substrate complex.
Samuele A; Kataropoulou A; Viola M; Zanoli S; La Regina G; Piscitelli F; Silvestri R; Maga G
Antiviral Res; 2009 Jan; 81(1):47-55. PubMed ID: 18984007
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and biological evaluation of 2',3'-didehydro-2',3'- dideoxy-5-fluorocytidine (D4FC) analogues: discovery of carbocyclic nucleoside triphosphates with potent inhibitory activity against HIV-1 reverse transcriptase.
Shi J; McAtee JJ; Schlueter Wirtz S; Tharnish P; Juodawlkis A; Liotta DC; Schinazi RF
J Med Chem; 1999 Mar; 42(5):859-67. PubMed ID: 10072683
[TBL] [Abstract][Full Text] [Related]
10. 2-Sulfonyl-4-chloroanilino moiety: a potent pharmacophore for the anti-human immunodeficiency virus type 1 activity of pyrrolyl aryl sulfones.
Artico M; Silvestri R; Massa S; Loi AG; Corrias S; Piras G; La Colla P
J Med Chem; 1996 Jan; 39(2):522-30. PubMed ID: 8558522
[TBL] [Abstract][Full Text] [Related]
11. Structure-based design, parallel synthesis, structure-activity relationship, and molecular modeling studies of thiocarbamates, new potent non-nucleoside HIV-1 reverse transcriptase inhibitor isosteres of phenethylthiazolylthiourea derivatives.
Ranise A; Spallarossa A; Cesarini S; Bondavalli F; Schenone S; Bruno O; Menozzi G; Fossa P; Mosti L; La Colla M; Sanna G; Murreddu M; Collu G; Busonera B; Marongiu ME; Pani A; La Colla P; Loddo R
J Med Chem; 2005 Jun; 48(11):3858-73. PubMed ID: 15916438
[TBL] [Abstract][Full Text] [Related]
12. Syntheses and biological evaluation of 5-(piperidin-1-yl)-3-phenyl-pentylsulfones as CCR5 antagonists.
Shankaran K; Donnelly KL; Shah SK; Caldwell CG; Chen P; Finke PE; Oates B; MacCoss M; Mills SG; DeMartino JA; Gould SL; Malkowitz L; Siciliano SJ; Springer MS; Kwei G; Carella A; Carver G; Danzeisen R; Hazuda D; Holmes K; Kessler J; Lineberger J; Miller MD; Emini EA; Schleif WA
Bioorg Med Chem Lett; 2004 Jul; 14(13):3589-93. PubMed ID: 15177481
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and evaluation of CCR5 antagonists containing modified 4-piperidinyl-2-phenyl-1-(phenylsulfonylamino)-butane.
Shah SK; Chen N; Guthikonda RN; Mills SG; Malkowitz L; Springer MS; Gould SL; Demartino JA; Carella A; Carver G; Holmes K; Schleif WA; Danzeisen R; Hazuda D; Kessler J; Lineberger J; Miller M; Emini EA; MacCoss M
Bioorg Med Chem Lett; 2005 Feb; 15(4):977-82. PubMed ID: 15686896
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and biological activity of novel nonnucleoside inhibitors of HIV-1 reverse transcriptase. 2-Aryl-substituted benzimidazoles.
Roth T; Morningstar ML; Boyer PL; Hughes SH; Buckheit RW; Michejda CJ
J Med Chem; 1997 Dec; 40(26):4199-207. PubMed ID: 9435891
[TBL] [Abstract][Full Text] [Related]
15. Nevirapine derivatives with broad-spectrum chemotherapeutic properties for the effective treatment of HIV/AIDS.
Sriram D; Srichakravarthy N; Bal TR; Yogeeswari P
Biomed Pharmacother; 2005 Sep; 59(8):456-9. PubMed ID: 16140495
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and biological evaluation of imidazole thioacetanilides as novel non-nucleoside HIV-1 reverse transcriptase inhibitors.
Zhan P; Liu X; Zhu J; Fang Z; Li Z; Pannecouque C; Clercq ED
Bioorg Med Chem; 2009 Aug; 17(16):5775-81. PubMed ID: 19643613
[TBL] [Abstract][Full Text] [Related]
17. Phenyl phosphoramidate derivatives of stavudine as anti-HIV agents with potent and selective in-vitro antiviral activity against adenovirus.
Uckun FM; Pendergrass S; Qazi S; Samuel P; Venkatachalam TK
Eur J Med Chem; 2004 Mar; 39(3):225-34. PubMed ID: 15051170
[TBL] [Abstract][Full Text] [Related]
18. Peptidyl allyl sulfones: a new class of inhibitors for clan CA cysteine proteases.
Götz MG; Caffrey CR; Hansell E; McKerrow JH; Powers JC
Bioorg Med Chem; 2004 Oct; 12(19):5203-11. PubMed ID: 15351403
[TBL] [Abstract][Full Text] [Related]
19. Indolyl aryl sulfones as HIV-1 non-nucleoside reverse transcriptase inhibitors: role of two halogen atoms at the indole ring in developing new analogues with improved antiviral activity.
Regina GL; Coluccia A; Piscitelli F; Bergamini A; Sinistro A; Cavazza A; Maga G; Samuele A; Zanoli S; Novellino E; Artico M; Silvestri R
J Med Chem; 2007 Oct; 50(20):5034-8. PubMed ID: 17803291
[TBL] [Abstract][Full Text] [Related]
20. High potency of indolyl aryl sulfone nonnucleoside inhibitors towards drug-resistant human immunodeficiency virus type 1 reverse transcriptase mutants is due to selective targeting of different mechanistic forms of the enzyme.
Cancio R; Silvestri R; Ragno R; Artico M; De Martino G; La Regina G; Crespan E; Zanoli S; Hübscher U; Spadari S; Maga G
Antimicrob Agents Chemother; 2005 Nov; 49(11):4546-54. PubMed ID: 16251294
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
