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7. Kupffer cell oxidant production is central to the mechanism of peroxisome proliferators. Rose ML; Rivera CA; Bradford BU; Graves LM; Cattley RC; Schoonhoven R; Swenberg JA; Thurman RG Carcinogenesis; 1999 Jan; 20(1):27-33. PubMed ID: 9934846 [TBL] [Abstract][Full Text] [Related]
8. Peroxisome proliferators do not increase DNA synthesis in purified rat hepatocytes. Parzefall W; Berger W; Kainzbauer E; Teufelhofer O; Schulte-Hermann R; Thurman RG Carcinogenesis; 2001 Mar; 22(3):519-23. PubMed ID: 11238195 [TBL] [Abstract][Full Text] [Related]
9. Relationship of hepatic peroxisome proliferation and replicative DNA synthesis to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid (Wy-14,643) in rats. Marsman DS; Cattley RC; Conway JG; Popp JA Cancer Res; 1988 Dec; 48(23):6739-44. PubMed ID: 3180084 [TBL] [Abstract][Full Text] [Related]
11. Peroxisome proliferator-activated receptor alpha is restricted to hepatic parenchymal cells, not Kupffer cells: implications for the mechanism of action of peroxisome proliferators in hepatocarcinogenesis. Peters JM; Rusyn I; Rose ML; Gonzalez FJ; Thurman RG Carcinogenesis; 2000 Apr; 21(4):823-6. PubMed ID: 10753222 [TBL] [Abstract][Full Text] [Related]
12. WY-14,643 induced cell proliferation and oxidative stress in mouse liver are independent of NADPH oxidase. Woods CG; Burns AM; Bradford BU; Ross PK; Kosyk O; Swenberg JA; Cunningham ML; Rusyn I Toxicol Sci; 2007 Aug; 98(2):366-74. PubMed ID: 17483499 [TBL] [Abstract][Full Text] [Related]
13. Time course investigation of PPARalpha- and Kupffer cell-dependent effects of WY-14,643 in mouse liver using microarray gene expression. Woods CG; Kosyk O; Bradford BU; Ross PK; Burns AM; Cunningham ML; Qu P; Ibrahim JG; Rusyn I Toxicol Appl Pharmacol; 2007 Dec; 225(3):267-77. PubMed ID: 17950772 [TBL] [Abstract][Full Text] [Related]
14. Wy-14,643, a peroxisome proliferator, inhibits compensative cell proliferation and hepatocyte growth factor mRNA expression in the rat liver. Motoki Y; Tamura H; Watanabe T; Suga T Cancer Lett; 1999 Jan; 135(2):145-50. PubMed ID: 10096422 [TBL] [Abstract][Full Text] [Related]
15. Novel role of oxidants in the molecular mechanism of action of peroxisome proliferators. Rusyn I; Rose ML; Bojes HK; Thurman RG Antioxid Redox Signal; 2000; 2(3):607-21. PubMed ID: 11229371 [TBL] [Abstract][Full Text] [Related]
16. Sustained formation of alpha-(4-pyridyl-1-oxide)-N-tert-butylnitrone radical adducts in mouse liver by peroxisome proliferators is dependent upon peroxisome proliferator-activated receptor-alpha, but not NADPH oxidase. Woods CG; Burns AM; Maki A; Bradford BU; Cunningham ML; Connor HD; Kadiiska MB; Mason RP; Peters JM; Rusyn I Free Radic Biol Med; 2007 Feb; 42(3):335-42. PubMed ID: 17210446 [TBL] [Abstract][Full Text] [Related]
17. Induction of sister chromatid exchange and micronuclei in primary cultures of rat and human hepatocytes by the peroxisome proliferator, Wy-14,643. Hwang JJ; Hsia MT; Jirtle RL Mutat Res; 1993 Apr; 286(2):123-33. PubMed ID: 7681523 [TBL] [Abstract][Full Text] [Related]
18. Peroxisomal proliferators inhibit acyl CoA synthetase and stimulate protein kinase C in vivo. Bojes HK; Thurman RG Toxicol Appl Pharmacol; 1994 Jun; 126(2):233-9. PubMed ID: 8209376 [TBL] [Abstract][Full Text] [Related]
19. Increased nuclear ploidy, not cell proliferation, is sustained in the peroxisome proliferator-treated rat liver. Lalwani ND; Dethloff LA; Haskins JR; Robertson DG; de la Iglesia FA Toxicol Pathol; 1997; 25(2):165-76. PubMed ID: 9125775 [TBL] [Abstract][Full Text] [Related]
20. Lack of comitogenicity by the peroxisome proliferator hepatocarcinogens, Wy-14,643 and clofibric acid. Marsman DS; Swanson-Pfeiffer CL; Popp JA Toxicol Appl Pharmacol; 1993 Sep; 122(1):1-6. PubMed ID: 8378924 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]