These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

827 related articles for article (PubMed ID: 9276639)

  • 1. Evidence for cytochrome P450 2A6 and 3A4 as major catalysts for N'-nitrosonornicotine alpha-hydroxylation by human liver microsomes.
    Patten CJ; Smith TJ; Friesen MJ; Tynes RE; Yang CS; Murphy SE
    Carcinogenesis; 1997 Aug; 18(8):1623-30. PubMed ID: 9276639
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Kinetic analysis of the activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by heterologously expressed human P450 enzymes and the effect of P450-specific chemical inhibitors on this activation in human liver microsomes.
    Patten CJ; Smith TJ; Murphy SE; Wang MH; Lee J; Tynes RE; Koch P; Yang CS
    Arch Biochem Biophys; 1996 Sep; 333(1):127-38. PubMed ID: 8806763
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Evidence for metabolic activation of N'-nitrosonornicotine and N-nitrosobenzylmethylamine by a rat nasal coumarin hydroxylase.
    Patten CJ; Peterson LA; Murphy SE
    Drug Metab Dispos; 1998 Feb; 26(2):177-80. PubMed ID: 9456305
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Specificity of cytochrome P450 2A3-catalyzed alpha-hydroxylation of N'-nitrosonornicotine enantiomers.
    Murphy SE; Isaac IS; Ding X; McIntee EJ
    Drug Metab Dispos; 2000 Nov; 28(11):1263-6. PubMed ID: 11038149
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Human reductive halothane metabolism in vitro is catalyzed by cytochrome P450 2A6 and 3A4.
    Spracklin DK; Thummel KE; Kharasch ED
    Drug Metab Dispos; 1996 Sep; 24(9):976-83. PubMed ID: 8886607
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes.
    Yamazaki H; Inui Y; Yun CH; Guengerich FP; Shimada T
    Carcinogenesis; 1992 Oct; 13(10):1789-94. PubMed ID: 1423839
    [TBL] [Abstract][Full Text] [Related]  

  • 7. N-Nitrosobenzylmethylamine hydroxylation and coumarin 7-hydroxylation: catalysis by rat esophageal microsomes and cytochrome P450 2A3 and 2A6 enzymes.
    von Weymarn LB; Felicia ND; Ding X; Murphy SE
    Chem Res Toxicol; 1999 Dec; 12(12):1254-61. PubMed ID: 10604876
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Characterization of cytochrome P450 2A4 and 2A5-catalyzed 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) metabolism.
    Felicia ND; Rekha GK; Murphy SE
    Arch Biochem Biophys; 2000 Dec; 384(2):418-24. PubMed ID: 11368333
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Comparative metabolism of N-nitrosopiperidine and N-nitrosopyrrolidine by rat liver and esophageal microsomes and cytochrome P450 2A3.
    Wong HL; Murphy SE; Wang M; Hecht SS
    Carcinogenesis; 2003 Feb; 24(2):291-300. PubMed ID: 12584180
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Catalytic role of cytochrome P4502B6 in the N-demethylation of S-mephenytoin.
    Heyn H; White RB; Stevens JC
    Drug Metab Dispos; 1996 Sep; 24(9):948-54. PubMed ID: 8886603
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cytochrome P450 2A-catalyzed metabolic activation of structurally similar carcinogenic nitrosamines: N'-nitrosonornicotine enantiomers, N-nitrosopiperidine, and N-nitrosopyrrolidine.
    Wong HL; Murphy SE; Hecht SS
    Chem Res Toxicol; 2005 Jan; 18(1):61-9. PubMed ID: 15651850
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by human cytochrome P450 1A2 and its inhibition by phenethyl isothiocyanate.
    Smith TJ; Guo Z; Guengerich FP; Yang CS
    Carcinogenesis; 1996 Apr; 17(4):809-13. PubMed ID: 8625495
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in human lung and liver microsomes and cytochromes P-450 expressed in hepatoma cells.
    Smith TJ; Guo Z; Gonzalez FJ; Guengerich FP; Stoner GD; Yang CS
    Cancer Res; 1992 Apr; 52(7):1757-63. PubMed ID: 1312898
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Preferential metabolic activation of N-nitrosopiperidine as compared to its structural homologue N-nitrosopyrrolidine by rat nasal mucosal microsomes.
    Wong HL; Murphy SE; Hecht SS
    Chem Res Toxicol; 2003 Oct; 16(10):1298-305. PubMed ID: 14565771
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evidence for a high-affinity enzyme in rat esophageal microsomes which alpha-hydroxylates N'-nitrosonornicotine.
    Murphy SE; Spina DA
    Carcinogenesis; 1994 Dec; 15(12):2709-13. PubMed ID: 8001225
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 2'-Hydroxylation of nicotine by cytochrome P450 2A6 and human liver microsomes: formation of a lung carcinogen precursor.
    Hecht SS; Hochalter JB; Villalta PW; Murphy SE
    Proc Natl Acad Sci U S A; 2000 Nov; 97(23):12493-7. PubMed ID: 11050152
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cytochrome P450 metabolic dealkylation of nine N-nitrosodialkylamines by human liver microsomes.
    Bellec G; Dréano Y; Lozach P; Ménez JF; Berthou F
    Carcinogenesis; 1996 Sep; 17(9):2029-34. PubMed ID: 8824531
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human lung microsomes by cytochromes P450, lipoxygenase, and hydroperoxides.
    Smith TJ; Stoner GD; Yang CS
    Cancer Res; 1995 Dec; 55(23):5566-73. PubMed ID: 7585636
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mechanism-based inactivation of human liver cytochrome P450 2A6 by 8-methoxypsoralen.
    Koenigs LL; Peter RM; Thompson SJ; Rettie AE; Trager WF
    Drug Metab Dispos; 1997 Dec; 25(12):1407-15. PubMed ID: 9394031
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Human liver microsomes are efficient catalysts of 1,3-butadiene oxidation: evidence for major roles by cytochromes P450 2A6 and 2E1.
    Duescher RJ; Elfarra AA
    Arch Biochem Biophys; 1994 Jun; 311(2):342-9. PubMed ID: 8203896
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 42.