These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

114 related articles for article (PubMed ID: 9278096)

  • 1. pH-dependent regulation of camptothecin-induced cytotoxicity and cleavable complex formation by the antimalarial agent chloroquine.
    Sorensen M; Sehested M; Jensen PB
    Biochem Pharmacol; 1997 Aug; 54(3):373-80. PubMed ID: 9278096
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting the cytotoxicity of topoisomerase II-directed epipodophyllotoxins to tumor cells in acidic environments.
    Jensen PB; Sørensen BS; Sehested M; Grue P; Demant EJ; Hansen HH
    Cancer Res; 1994 Jun; 54(11):2959-63. PubMed ID: 8187081
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Effect of cellular ATP depletion on topoisomerase II poisons. Abrogation Of cleavable-complex formation by etoposide but not by amsacrine.
    Sorensen M; Sehested M; Jensen PB
    Mol Pharmacol; 1999 Mar; 55(3):424-31. PubMed ID: 10051525
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Next generation topoisomerase I inhibitors: Rationale and biomarker strategies.
    Teicher BA
    Biochem Pharmacol; 2008 Mar; 75(6):1262-71. PubMed ID: 18061144
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Camptothecin analogues with enhanced antitumor activity at acidic pH.
    Adams DJ; Dewhirst MW; Flowers JL; Gamcsik MP; Colvin OM; Manikumar G; Wani MC; Wall ME
    Cancer Chemother Pharmacol; 2000; 46(4):263-71. PubMed ID: 11052623
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Camptothecin resistance is determined by the regulation of topoisomerase I degradation mediated by ubiquitin proteasome pathway.
    Ando K; Shah AK; Sachdev V; Kleinstiver BP; Taylor-Parker J; Welch MM; Hu Y; Salgia R; White FM; Parvin JD; Ozonoff A; Rameh LE; Joung JK; Bharti AK
    Oncotarget; 2017 Jul; 8(27):43733-43751. PubMed ID: 28415827
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibitors of topoisomerase II as pH-dependent modulators of etoposide-mediated cytotoxicity.
    Langer SW; Schmidt G; Sørensen M; Sehested M; Jensen PB
    Clin Cancer Res; 1999 Oct; 5(10):2899-907. PubMed ID: 10537359
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 2-deoxy-D-glucose enhances the cytotoxicity of topoisomerase inhibitors in human tumor cell lines.
    Dwarakanath BS; Khaitan D; Ravindranath T
    Cancer Biol Ther; 2004 Sep; 3(9):864-70. PubMed ID: 15254410
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Antagonistic effect of aclarubicin on camptothecin induced cytotoxicity: role of topoisomerase I.
    Sørensen BS; Jensen PB; Sehested M; Jensen PS; Kjeldsen E; Nielsen OF; Alsner J
    Biochem Pharmacol; 1994 Jun; 47(11):2105-10. PubMed ID: 8010996
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Differential cytotoxic pathways of topoisomerase I and II anticancer agents after overexpression of the E2F-1/DP-1 transcription factor complex.
    Hofland K; Petersen BO; Falck J; Helin K; Jensen PB; Sehested M
    Clin Cancer Res; 2000 Apr; 6(4):1488-97. PubMed ID: 10778981
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The novel poly(ADP-Ribose) polymerase inhibitor, AG14361, sensitizes cells to topoisomerase I poisons by increasing the persistence of DNA strand breaks.
    Smith LM; Willmore E; Austin CA; Curtin NJ
    Clin Cancer Res; 2005 Dec; 11(23):8449-57. PubMed ID: 16322308
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Sequential administration of camptothecin and etoposide circumvents the antagonistic cytotoxicity of simultaneous drug administration in slowly growing human colon carcinoma HT-29 cells.
    Bertrand R; O'Connor PM; Kerrigan D; Pommier Y
    Eur J Cancer; 1992; 28A(4-5):743-8. PubMed ID: 1326304
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Rescue of Schizosaccharomyces pombe from camptothecin-mediated death by a DNA topoisomerase I inhibitor, TAN-1518 A.
    Horiguchi T; Tanida S
    Biochem Pharmacol; 1995 May; 49(10):1395-401. PubMed ID: 7763282
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Induction of biphasic DNA double strand breaks and activation of multiple repair protein complexes by DNA topoisomerase I drug 7-ethyl-10-hydroxy-camptothecin.
    Wu J; Yin MB; Hapke G; Tóth K; Rustum YM
    Mol Pharmacol; 2002 Apr; 61(4):742-8. PubMed ID: 11901212
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Induction of neuronal apoptosis by camptothecin, an inhibitor of DNA topoisomerase-I: evidence for cell cycle-independent toxicity.
    Morris EJ; Geller HM
    J Cell Biol; 1996 Aug; 134(3):757-70. PubMed ID: 8707853
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mechanism of cytotoxicity of N-[2-(dimethylamino)ethyl] acridine-4-carboxamide and of its 7-chloro derivative: the roles of topoisomerases I and II.
    Bridewell DJ; Finlay GJ; Baguley BC
    Cancer Chemother Pharmacol; 1999; 43(4):302-8. PubMed ID: 10071981
    [TBL] [Abstract][Full Text] [Related]  

  • 17. DNA damage and cell killing by camptothecin and its derivative in human leukemia HL-60 cells.
    Yoshida A; Ueda T; Wano Y; Nakamura T
    Jpn J Cancer Res; 1993 May; 84(5):566-73. PubMed ID: 8391526
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characterization of novel human leukemic cell lines selected for resistance to merbarone, a catalytic inhibitor of DNA topoisomerase II.
    Kusumoto H; Rodgers QE; Boege F; Raimondi SC; Beck WT
    Cancer Res; 1996 Jun; 56(11):2573-83. PubMed ID: 8653700
    [TBL] [Abstract][Full Text] [Related]  

  • 19. DNA topoisomerase II rescue by catalytic inhibitors: a new strategy to improve the antitumor selectivity of etoposide.
    Jensen PB; Sehested M
    Biochem Pharmacol; 1997 Oct; 54(7):755-9. PubMed ID: 9353129
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The role of the DNA mismatch repair system in the cytotoxicity of the topoisomerase inhibitors camptothecin and etoposide to human colorectal cancer cells.
    Jacob S; Aguado M; Fallik D; Praz F
    Cancer Res; 2001 Sep; 61(17):6555-62. PubMed ID: 11522654
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.