BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

184 related articles for article (PubMed ID: 9285556)

  • 1. Mutations of critical amino acids affect the biological and biochemical properties of oncogenic A-Raf and Raf-1.
    Bosch E; Cherwinski H; Peterson D; McMahon M
    Oncogene; 1997 Aug; 15(9):1021-33. PubMed ID: 9285556
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Development of a conditional in vivo model to evaluate the efficacy of small molecule inhibitors for the treatment of Raf-transformed hematopoietic cells.
    Konopleva M; Shi Y; Steelman LS; Shelton JG; Munsell M; Marini F; McQueen T; Contractor R; McCubrey JA; Andreeff M
    Cancer Res; 2005 Nov; 65(21):9962-70. PubMed ID: 16267021
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Differential abilities of activated Raf oncoproteins to abrogate cytokine dependency, prevent apoptosis and induce autocrine growth factor synthesis in human hematopoietic cells.
    McCubrey JA; Steelman LS; Hoyle PE; Blalock WL; Weinstein-Oppenheimer C; Franklin RA; Cherwinski H; Bosch E; McMahon M
    Leukemia; 1998 Dec; 12(12):1903-29. PubMed ID: 9844921
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Conditionally oncogenic forms of the A-Raf and B-Raf protein kinases display different biological and biochemical properties in NIH 3T3 cells.
    Pritchard CA; Samuels ML; Bosch E; McMahon M
    Mol Cell Biol; 1995 Nov; 15(11):6430-42. PubMed ID: 7565795
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulation of A-raf expression.
    Lee JE; Beck TW; Wojnowski L; Rapp UR
    Oncogene; 1996 Apr; 12(8):1669-77. PubMed ID: 8622887
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Differential abilities of the Raf family of protein kinases to abrogate cytokine dependency and prevent apoptosis in murine hematopoietic cells by a MEK1-dependent mechanism.
    Hoyle PE; Moye PW; Steelman LS; Blalock WL; Franklin RA; Pearce M; Cherwinski H; Bosch E; McMahon M; McCubrey JA
    Leukemia; 2000 Apr; 14(4):642-56. PubMed ID: 10764150
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mutagenic analysis of functional domains of the mos proto-oncogene and identification of the sites important for MAPK activation and DNA binding.
    Fukasawa K; Zhou R; Matten WT; Armstrong AJ; Daar I; Oskarsson M; Sathyanarayana BK; Maclvor L; Wood TG; Vande Woude GF
    Oncogene; 1995 Oct; 11(8):1447-57. PubMed ID: 7478569
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Rapid phosphorylation of Ets-2 accompanies mitogen-activated protein kinase activation and the induction of heparin-binding epidermal growth factor gene expression by oncogenic Raf-1.
    McCarthy SA; Chen D; Yang BS; Garcia Ramirez JJ; Cherwinski H; Chen XR; Klagsbrun M; Hauser CA; Ostrowski MC; McMahon M
    Mol Cell Biol; 1997 May; 17(5):2401-12. PubMed ID: 9111309
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1.
    Woods D; Parry D; Cherwinski H; Bosch E; Lees E; McMahon M
    Mol Cell Biol; 1997 Sep; 17(9):5598-611. PubMed ID: 9271435
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Autophosphorylation modulates the kinase activity and oncogenic potential of the Met receptor tyrosine kinase.
    Rodrigues GA; Park M
    Oncogene; 1994 Jul; 9(7):2019-27. PubMed ID: 8208547
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Isolation of temperature-sensitive mutations in the c-raf-1 catalytic domain and expression of conditionally active and dominant-defective forms of Raf-1 in cultured mammalian cells.
    Lu KK; Bazarov AV; Yoon LS; Sedivy JM
    Cell Growth Differ; 1998 May; 9(5):367-80. PubMed ID: 9607558
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Rit, a non-lipid-modified Ras-related protein, transforms NIH3T3 cells without activating the ERK, JNK, p38 MAPK or PI3K/Akt pathways.
    Rusyn EV; Reynolds ER; Shao H; Grana TM; Chan TO; Andres DA; Cox AD
    Oncogene; 2000 Sep; 19(41):4685-94. PubMed ID: 11032018
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Correlation of constitutive activation of raf-1 with morphological transformation and abrogation of tyrosine phosphorylation of distinct sets of proteins in human squamous carcinoma cells.
    Patel BK; Ray S; Whiteside TL; Kasid U
    Mol Carcinog; 1997 Jan; 18(1):1-6. PubMed ID: 9022807
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural and functional domains critical for constitutive activation of the HGF-receptor (Met).
    Zhen Z; Giordano S; Longati P; Medico E; Campiglio M; Comoglio PM
    Oncogene; 1994 Jun; 9(6):1691-7. PubMed ID: 8183564
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A different function for a critical tryptophan in c-Raf and Hck.
    McPherson RA; Taylor MM; Hershey ED; Sturgill TW
    Oncogene; 2000 Jul; 19(32):3616-22. PubMed ID: 10951567
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of a transforming activity suppressing sequence in the c-raf oncogene.
    Ishikawa F; Sakai R; Ochiai M; Takaku F; Sugimura T; Nagao M
    Oncogene; 1988 Dec; 3(6):653-8. PubMed ID: 2577866
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Activation of Raf-1 in human pancreatic adenocarcinoma.
    Berger DH; Jardines LA; Chang H; Ruggeri B
    J Surg Res; 1997 Apr; 69(1):199-204. PubMed ID: 9202670
    [TBL] [Abstract][Full Text] [Related]  

  • 18. v-Rel and c-Rel are differentially affected by mutations at a consensus protein kinase recognition sequence.
    Mosialos G; Gilmore TD
    Oncogene; 1993 Mar; 8(3):721-30. PubMed ID: 8437855
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1.
    Zhang XF; Settleman J; Kyriakis JM; Takeuchi-Suzuki E; Elledge SJ; Marshall MS; Bruder JT; Rapp UR; Avruch J
    Nature; 1993 Jul; 364(6435):308-13. PubMed ID: 8332187
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Distinct activation mechanisms of protein kinase B by growth-factor stimulation and heat-shock treatment.
    Matsuzaki H; Yamamoto T; Kikkawa U
    Biochemistry; 2004 Apr; 43(14):4284-93. PubMed ID: 15065872
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.