These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

302 related articles for article (PubMed ID: 9299599)

  • 1. Embryonic delivered dose of isotretinoin (13-cis-retinoic acid) and its metabolites in hamsters.
    Eckhoff C; Willhite CC
    Toxicol Appl Pharmacol; 1997 Sep; 146(1):79-87. PubMed ID: 9299599
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Teratogenicity and transplacental pharmacokinetics of 13-cis-retinoic acid in rabbits.
    Eckhoff C; Chari S; Kromka M; Staudner H; Juhasz L; Rudiger H; Agnish N
    Toxicol Appl Pharmacol; 1994 Mar; 125(1):34-41. PubMed ID: 8128493
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Maternal toxicokinetics, metabolism, and embryo exposure following a teratogenic dosing regimen with 13-cis-retinoic acid (isotretinoin) in the cynomolgus monkey.
    Hummler H; Hendrickx AG; Nau H
    Teratology; 1994 Sep; 50(3):184-93. PubMed ID: 7871482
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Distribution, teratogenicity, and embryonic delivered dose of retinoid Ro 23-9223.
    Willhite CC; Lovey A; Eckhoff C
    Toxicol Appl Pharmacol; 2000 Apr; 164(2):171-5. PubMed ID: 10764630
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Retinoid metabolism and transplacental pharmacokinetics in the cynomolgus monkey following a nonteratogenic dosing regimen with all-trans-retinoic acid.
    Tzimas G; Nau H; Hendrickx AG; Peterson PE; Hummler H
    Teratology; 1996 Nov; 54(5):255-65. PubMed ID: 9035347
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The high sensitivity of the rabbit to the teratogenic effects of 13-cis-retinoic acid (isotretinoin) is a consequence of prolonged exposure of the embryo to 13-cis-retinoic acid and 13-cis-4-oxo-retinoic acid, and not of isomerization to all-trans-retinoic acid.
    Tzimas G; Bürgin H; Collins MD; Hummler H; Nau H
    Arch Toxicol; 1994; 68(2):119-28. PubMed ID: 8179481
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Plasma pharmacokinetics and metabolism of 13-cis- and all-trans-retinoic acid in the cynomolgus monkey and the identification of 13-cis- and all-trans-retinoyl-beta-glucuronides. A comparison to one human case study with isotretinoin.
    Kraft JC; Slikker W; Bailey JR; Roberts LG; Fischer B; Wittfoht W; Nau H
    Drug Metab Dispos; 1991; 19(2):317-24. PubMed ID: 1676630
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Single versus multiple dose administration of all-trans-retinoic acid during organogenesis: differential metabolism and transplacental kinetics in rat and rabbit.
    Collins MD; Tzimas G; Bürgin H; Hummler H; Nau H
    Toxicol Appl Pharmacol; 1995 Jan; 130(1):9-18. PubMed ID: 7839374
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Teratogenicity of isotretinoin revisited: species variation and the role of all-trans-retinoic acid.
    Nau H
    J Am Acad Dermatol; 2001 Nov; 45(5):S183-7. PubMed ID: 11606951
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Placental transfer and developmental effects of 9-cis retinoic acid in mice.
    Kochhar DM; Jiang H; Penner JD; Heyman RA
    Teratology; 1995 Apr; 51(4):257-65. PubMed ID: 7570368
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Comparative teratology and transplacental pharmacokinetics of all-trans-retinoic acid, 13-cis-retinoic acid, and retinyl palmitate following daily administrations in rats.
    Collins MD; Tzimas G; Hummler H; Bürgin H; Nau H
    Toxicol Appl Pharmacol; 1994 Jul; 127(1):132-44. PubMed ID: 8048045
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Comparative disposition, receptor affinity, and teratogenic activity of sulfon arotinoids.
    Willhite CC; Dubois A; Schindler-Horvat J; Apfel C; Eckhoff C
    Teratology; 1995 Sep; 52(3):169-75. PubMed ID: 8638257
    [TBL] [Abstract][Full Text] [Related]  

  • 13. All-trans-retinoic acid in maternal plasma and teratogenicity in rats and rabbits.
    Tembe EA; Honeywell R; Buss NE; Renwick AG
    Toxicol Appl Pharmacol; 1996 Dec; 141(2):456-72. PubMed ID: 8975771
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Topical delivery of 13-cis-retinoic acid by inhalation up-regulates expression of rodent lung but not liver retinoic acid receptors.
    Wang DL; Marko M; Dahl AR; Engelke KS; Placke ME; Imondi AR; Mulshine JL; De Luca LM
    Clin Cancer Res; 2000 Sep; 6(9):3636-45. PubMed ID: 10999756
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The area under the concentration-time curve of all-trans-retinoic acid is the most suitable pharmacokinetic correlate to the embryotoxicity of this retinoid in the rat.
    Tzimas G; Thiel R; Chahoud I; Nau H
    Toxicol Appl Pharmacol; 1997 Apr; 143(2):436-44. PubMed ID: 9144460
    [TBL] [Abstract][Full Text] [Related]  

  • 16. All-trans-retinoyl-beta-glucuronide is a potent teratogen in the mouse because of extensive metabolism to all-trans-retinoic acid.
    Nau H; Elmazar MM; Rühl R; Thiel R; Sass JO
    Teratology; 1996 Sep; 54(3):150-6. PubMed ID: 8987158
    [TBL] [Abstract][Full Text] [Related]  

  • 17. NTP technical report on the toxicity and metabolism studies of chloral hydrate (CAS No. 302-17-0). Administered by gavage to F344/N rats and B6C3F1 mice.
    Beland FA
    Toxic Rep Ser; 1999 Aug; (59):1-66, A1-E7. PubMed ID: 11803702
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Critical period for a teratogenic VLA-4 antagonist: Developmental effects and comparison of embryo drug concentrations of teratogenic and non-teratogenic VLA-4 antagonists.
    Crofts F; Rohatagi S; Pino M; DeLise B; Zhang J; Nguyen M; Guittin P; Barbellion S; Brunel P; Hofmann T; Schmidt J; Wong M; Lockey P; Lerman S; Clark R
    Birth Defects Res B Dev Reprod Toxicol; 2004 Apr; 71(2):69-79. PubMed ID: 15098200
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pharmacokinetic assessment of teratologically effective concentrations of an endogenous retinoic acid metabolite.
    Satre MA; Penner JD; Kochhar DM
    Teratology; 1989 Apr; 39(4):341-8. PubMed ID: 2749577
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Developmental stage-associated differences in the transplacental distribution of 13-cis- and all-trans-retinoic acid as well as their glucuronides in rats and mice.
    Tzimas G; Collins MD; Nau H
    Toxicol Appl Pharmacol; 1995 Jul; 133(1):91-101. PubMed ID: 7597714
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.