168 related articles for article (PubMed ID: 9299618)
1. A single sequence change destabilizes the influenza virus neuraminidase tetramer.
Colacino JM; Chirgadze NY; Garman E; Murti KG; Loncharich RJ; Baxter AJ; Staschke KA; Laver WG
Virology; 1997 Sep; 236(1):66-75. PubMed ID: 9299618
[TBL] [Abstract][Full Text] [Related]
2. Molecular basis for the resistance of influenza viruses to 4-guanidino-Neu5Ac2en.
Staschke KA; Colacino JM; Baxter AJ; Air GM; Bansal A; Hornback WJ; Munroe JE; Laver WG
Virology; 1995 Dec; 214(2):642-6. PubMed ID: 8553569
[TBL] [Abstract][Full Text] [Related]
3. Generation and characterization of an influenza virus neuraminidase variant with decreased sensitivity to the neuraminidase-specific inhibitor 4-guanidino-Neu5Ac2en.
Blick TJ; Tiong T; Sahasrabudhe A; Varghese JN; Colman PM; Hart GJ; Bethell RC; McKimm-Breschkin JL
Virology; 1995 Dec; 214(2):475-84. PubMed ID: 8553549
[TBL] [Abstract][Full Text] [Related]
4. Mutations affecting the sensitivity of the influenza virus neuraminidase to 4-guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid.
Goto H; Bethell RC; Kawaoka Y
Virology; 1997 Nov; 238(2):265-72. PubMed ID: 9400599
[TBL] [Abstract][Full Text] [Related]
5. Substrate, inhibitor, or antibody stabilizes the Glu 119 Gly mutant influenza virus neuraminidase.
Sahasrabudhe A; Lawrence L; Epa VC; Varghese JN; Colman PM; McKimm-Breschkin JL
Virology; 1998 Jul; 247(1):14-21. PubMed ID: 9683567
[TBL] [Abstract][Full Text] [Related]
6. Dihydropyrancarboxamides related to zanamivir: a new series of inhibitors of influenza virus sialidases. 2. Crystallographic and molecular modeling study of complexes of 4-amino-4H-pyran-6-carboxamides and sialidase from influenza virus types A and B.
Taylor NR; Cleasby A; Singh O; Skarzynski T; Wonacott AJ; Smith PW; Sollis SL; Howes PD; Cherry PC; Bethell R; Colman P; Varghese J
J Med Chem; 1998 Mar; 41(6):798-807. PubMed ID: 9526556
[TBL] [Abstract][Full Text] [Related]
7. Mutations conferring zanamivir resistance in human influenza virus N2 neuraminidases compromise virus fitness and are not stably maintained in vitro.
Zürcher T; Yates PJ; Daly J; Sahasrabudhe A; Walters M; Dash L; Tisdale M; McKimm-Breschkin JL
J Antimicrob Chemother; 2006 Oct; 58(4):723-32. PubMed ID: 16891631
[TBL] [Abstract][Full Text] [Related]
8. Mutation in the influenza virus neuraminidase gene resulting in decreased sensitivity to the neuraminidase inhibitor 4-guanidino-Neu5Ac2en leads to instability of the enzyme.
McKimm-Breschkin JL; McDonald M; Blick TJ; Colman PM
Virology; 1996 Nov; 225(1):240-2. PubMed ID: 8918554
[TBL] [Abstract][Full Text] [Related]
9. Three-dimensional structure of influenza A N9 neuraminidase and its complex with the inhibitor 2-deoxy 2,3-dehydro-N-acetyl neuraminic acid.
Bossart-Whitaker P; Carson M; Babu YS; Smith CD; Laver WG; Air GM
J Mol Biol; 1993 Aug; 232(4):1069-83. PubMed ID: 8371267
[TBL] [Abstract][Full Text] [Related]
10. Selection of influenza A and B viruses for resistance to 4-guanidino-Neu5Ac2en in cell culture.
Colacino JM; Laver WG; Air GM
J Infect Dis; 1997 Aug; 176 Suppl 1():S66-8. PubMed ID: 9240698
[TBL] [Abstract][Full Text] [Related]
11. Catalytic and framework mutations in the neuraminidase active site of influenza viruses that are resistant to 4-guanidino-Neu5Ac2en.
Gubareva LV; Robinson MJ; Bethell RC; Webster RG
J Virol; 1997 May; 71(5):3385-90. PubMed ID: 9094607
[TBL] [Abstract][Full Text] [Related]
12. Three-dimensional structure of the complex of 4-guanidino-Neu5Ac2en and influenza virus neuraminidase.
Varghese JN; Epa VC; Colman PM
Protein Sci; 1995 Jun; 4(6):1081-7. PubMed ID: 7549872
[TBL] [Abstract][Full Text] [Related]
13. 2,3-didehydro-2,4-dideoxy-4-guanidino-N-acetyl-D-neuraminic acid (4-guanidino-Neu5Ac2en) is a slow-binding inhibitor of sialidase from both influenza A virus and influenza B virus.
Hart GJ; Bethell RC
Biochem Mol Biol Int; 1995 Jul; 36(4):695-703. PubMed ID: 8528132
[TBL] [Abstract][Full Text] [Related]
14. Insights from modeling the 3D structure of H5N1 influenza virus neuraminidase and its binding interactions with ligands.
Wei DQ; Du QS; Sun H; Chou KC
Biochem Biophys Res Commun; 2006 Jun; 344(3):1048-55. PubMed ID: 16647045
[TBL] [Abstract][Full Text] [Related]
15. Genetic analysis reveals that both haemagglutinin and neuraminidase determine the sensitivity of naturally occurring avian influenza viruses to zanamivir in vitro.
Baigent SJ; Bethell RC; McCauley JW
Virology; 1999 Oct; 263(2):323-38. PubMed ID: 10544106
[TBL] [Abstract][Full Text] [Related]
16. Mutations in a conserved residue in the influenza virus neuraminidase active site decreases sensitivity to Neu5Ac2en-derived inhibitors.
McKimm-Breschkin JL; Sahasrabudhe A; Blick TJ; McDonald M; Colman PM; Hart GJ; Bethell RC; Varghese JN
J Virol; 1998 Mar; 72(3):2456-62. PubMed ID: 9499107
[TBL] [Abstract][Full Text] [Related]
17. The interaction of neuraminidase and hemagglutinin mutations in influenza virus in resistance to 4-guanidino-Neu5Ac2en.
Blick TJ; Sahasrabudhe A; McDonald M; Owens IJ; Morley PJ; Fenton RJ; McKimm-Breschkin JL
Virology; 1998 Jun; 246(1):95-103. PubMed ID: 9656997
[TBL] [Abstract][Full Text] [Related]
18. Novel aromatic inhibitors of influenza virus neuraminidase make selective interactions with conserved residues and water molecules in the active site.
Finley JB; Atigadda VR; Duarte F; Zhao JJ; Brouillette WJ; Air GM; Luo M
J Mol Biol; 1999 Nov; 293(5):1107-19. PubMed ID: 10547289
[TBL] [Abstract][Full Text] [Related]
19. Critical interactions in binding antibody NC41 to influenza N9 neuraminidase: amino acid contacts on the antibody heavy chain.
Pruett PS; Air GM
Biochemistry; 1998 Jul; 37(30):10660-70. PubMed ID: 9692956
[TBL] [Abstract][Full Text] [Related]
20. Binding interaction analysis of the active site and its inhibitors for neuraminidase (N1 subtype) of human influenza virus by the integration of molecular docking, FMO calculation and 3D-QSAR CoMFA modeling.
Zhang Q; Yang J; Liang K; Feng L; Li S; Wan J; Xu X; Yang G; Liu D; Yang S
J Chem Inf Model; 2008 Sep; 48(9):1802-12. PubMed ID: 18707092
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
