416 related articles for article (PubMed ID: 9307274)
1. Induction of p21waf1 expression and growth inhibition by transforming growth factor beta involve the tumor suppressor gene DPC4 in human pancreatic adenocarcinoma cells.
Grau AM; Zhang L; Wang W; Ruan S; Evans DB; Abbruzzese JL; Zhang W; Chiao PJ
Cancer Res; 1997 Sep; 57(18):3929-34. PubMed ID: 9307274
[TBL] [Abstract][Full Text] [Related]
2. Suppression of tumorigenesis and induction of p15(ink4b) by Smad4/DPC4 in human pancreatic cancer cells.
Peng B; Fleming JB; Breslin T; Grau AM; Fojioka S; Abbruzzese JL; Evans DB; Ayers D; Wathen K; Wu T; Robertson KD; Chiao PJ
Clin Cancer Res; 2002 Nov; 8(11):3628-38. PubMed ID: 12429655
[TBL] [Abstract][Full Text] [Related]
3. Overexpression of the tumor suppressor gene Smad4/DPC4 induces p21waf1 expression and growth inhibition in human carcinoma cells.
Hunt KK; Fleming JB; Abramian A; Zhang L; Evans DB; Chiao PJ
Cancer Res; 1998 Dec; 58(24):5656-61. PubMed ID: 9865717
[TBL] [Abstract][Full Text] [Related]
4. Differential expression of transforming growth factor beta receptors in human pancreatic adenocarcinoma.
Venkatasubbarao K; Ahmed MM; Mohiuddin M; Swiderski C; Lee E; Gower WR; Salhab KF; McGrath P; Strodel W; Freeman JW
Anticancer Res; 2000; 20(1A):43-51. PubMed ID: 10769633
[TBL] [Abstract][Full Text] [Related]
5. DPC4 (SMAD4) mediates transforming growth factor-beta1 (TGF-beta1) induced growth inhibition and transcriptional response in breast tumour cells.
de Winter JP; Roelen BA; ten Dijke P; van der Burg B; van den Eijnden-van Raaij AJ
Oncogene; 1997 Apr; 14(16):1891-9. PubMed ID: 9150356
[TBL] [Abstract][Full Text] [Related]
6. Expression of Smad4 in the FaDu cell line partially restores TGF-beta growth inhibition but is not sufficient to regulate fibronectin expression or suppress tumorigenicity.
Hummer BT; Bartlett C; Henry E; Weissman BE
J Cell Physiol; 2003 Mar; 194(3):289-302. PubMed ID: 12548549
[TBL] [Abstract][Full Text] [Related]
7. Tumor suppressor gene Smad4/DPC4, its downstream target genes, and regulation of cell cycle.
Chiao PJ; Hunt KK; Grau AM; Abramian A; Fleming J; Zhang W; Breslin T; Abbruzzese JL; Evans DB
Ann N Y Acad Sci; 1999 Jun; 880():31-7. PubMed ID: 10415848
[TBL] [Abstract][Full Text] [Related]
8. Smad4-independent regulation of p21/WAF1 by transforming growth factor-beta.
Ijichi H; Otsuka M; Tateishi K; Ikenoue T; Kawakami T; Kanai F; Arakawa Y; Seki N; Shimizu K; Miyazono K; Kawabe T; Omata M
Oncogene; 2004 Feb; 23(5):1043-51. PubMed ID: 14762439
[TBL] [Abstract][Full Text] [Related]
9. Sensitivity to transforming growth factor beta 1-induced growth arrest is common in human squamous cell carcinoma cell lines: c-MYC down-regulation and p21waf1 induction are important early events.
Malliri A; Yeudall WA; Nikolic M; Crouch DH; Parkinson EK; Ozanne B
Cell Growth Differ; 1996 Oct; 7(10):1291-304. PubMed ID: 8891333
[TBL] [Abstract][Full Text] [Related]
10. Restoration of SMAD4 by gene therapy reverses the invasive phenotype in pancreatic adenocarcinoma cells.
Duda DG; Sunamura M; Lefter LP; Furukawa T; Yokoyama T; Yatsuoka T; Abe T; Inoue H; Motoi F; Egawa S; Matsuno S; Horii A
Oncogene; 2003 Oct; 22(44):6857-64. PubMed ID: 14534532
[TBL] [Abstract][Full Text] [Related]
11. A role for human MUC4 mucin gene, the ErbB2 ligand, as a target of TGF-beta in pancreatic carcinogenesis.
Jonckheere N; Perrais M; Mariette C; Batra SK; Aubert JP; Pigny P; Van Seuningen I
Oncogene; 2004 Jul; 23(34):5729-38. PubMed ID: 15184872
[TBL] [Abstract][Full Text] [Related]
12. Farnesyltransferase inhibitor (L-744,832) restores TGF-beta type II receptor expression and enhances radiation sensitivity in K-ras mutant pancreatic cancer cell line MIA PaCa-2.
Alcock RA; Dey S; Chendil D; Inayat MS; Mohiuddin M; Hartman G; Chatfield LK; Gallicchio VS; Ahmed MM
Oncogene; 2002 Nov; 21(51):7883-90. PubMed ID: 12420225
[TBL] [Abstract][Full Text] [Related]
13. Smad4 silencing in pancreatic cancer cell lines using stable RNA interference and gene expression profiles induced by transforming growth factor-beta.
Jazag A; Ijichi H; Kanai F; Imamura T; Guleng B; Ohta M; Imamura J; Tanaka Y; Tateishi K; Ikenoue T; Kawakami T; Arakawa Y; Miyagishi M; Taira K; Kawabe T; Omata M
Oncogene; 2005 Jan; 24(4):662-71. PubMed ID: 15592526
[TBL] [Abstract][Full Text] [Related]
14. Genetic alterations of the transforming growth factor beta receptor genes in pancreatic and biliary adenocarcinomas.
Goggins M; Shekher M; Turnacioglu K; Yeo CJ; Hruban RH; Kern SE
Cancer Res; 1998 Dec; 58(23):5329-32. PubMed ID: 9850059
[TBL] [Abstract][Full Text] [Related]
15. DPC4/SMAD4 mediated tumor suppression of colon carcinoma cells is associated with reduced urokinase expression.
Schwarte-Waldhoff I; Klein S; Blass-Kampmann S; Hintelmann A; Eilert C; Dreschers S; Kalthoff H; Hahn SA; Schmiegel W
Oncogene; 1999 May; 18(20):3152-8. PubMed ID: 10340387
[TBL] [Abstract][Full Text] [Related]
16. Attenuation of the TGF-beta-Smad signaling pathway in pancreatic tumor cells confers resistance to TGF-beta-induced growth arrest.
Nicolás FJ; Hill CS
Oncogene; 2003 Jun; 22(24):3698-711. PubMed ID: 12802277
[TBL] [Abstract][Full Text] [Related]
17. Targeting endogenous transforming growth factor beta receptor signaling in SMAD4-deficient human pancreatic carcinoma cells inhibits their invasive phenotype1.
Subramanian G; Schwarz RE; Higgins L; McEnroe G; Chakravarty S; Dugar S; Reiss M
Cancer Res; 2004 Aug; 64(15):5200-11. PubMed ID: 15289325
[TBL] [Abstract][Full Text] [Related]
18. Overexpression of transforming growth factor (TGF) beta1 type II receptor restores TGF-beta1 sensitivity and signaling in human prostate cancer cells.
Guo Y; Kyprianou N
Cell Growth Differ; 1998 Feb; 9(2):185-93. PubMed ID: 9486855
[TBL] [Abstract][Full Text] [Related]
19. Rap1 reverses transcriptional repression of TGF-beta type II receptor by a mechanism involving AP-1 in the human pancreatic cancer cell line, UK Pan-1.
Fralix KD; Zhao S; Venkatasubbarao K; Freeman JW
J Cell Physiol; 2003 Jan; 194(1):88-99. PubMed ID: 12447993
[TBL] [Abstract][Full Text] [Related]
20. Regulatory mechanisms for transforming growth factor beta as an autocrine inhibitor in human hepatocellular carcinoma: implications for roles of smads in its growth.
Matsuzaki K; Date M; Furukawa F; Tahashi Y; Matsushita M; Sugano Y; Yamashiki N; Nakagawa T; Seki T; Nishizawa M; Fujisawa J; Inoue K
Hepatology; 2000 Aug; 32(2):218-27. PubMed ID: 10915727
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]