192 related articles for article (PubMed ID: 9314549)
1. Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice.
Kägi D; Odermatt B; Seiler P; Zinkernagel RM; Mak TW; Hengartner H
J Exp Med; 1997 Oct; 186(7):989-97. PubMed ID: 9314549
[TBL] [Abstract][Full Text] [Related]
2. Development of insulitis without diabetes in transgenic mice lacking perforin-dependent cytotoxicity.
Kägi D; Odermatt B; Ohashi PS; Zinkernagel RM; Hengartner H
J Exp Med; 1996 May; 183(5):2143-52. PubMed ID: 8642324
[TBL] [Abstract][Full Text] [Related]
3. Islet-specific expression of IL-10 promotes diabetes in nonobese diabetic mice independent of Fas, perforin, TNF receptor-1, and TNF receptor-2 molecules.
Balasa B; Van Gunst K; Jung N; Balakrishna D; Santamaria P; Hanafusa T; Itoh N; Sarvetnick N
J Immunol; 2000 Sep; 165(5):2841-9. PubMed ID: 10946317
[TBL] [Abstract][Full Text] [Related]
4. Perforin-independent beta-cell destruction by diabetogenic CD8(+) T lymphocytes in transgenic nonobese diabetic mice.
Amrani A; Verdaguer J; Anderson B; Utsugi T; Bou S; Santamaria P
J Clin Invest; 1999 Apr; 103(8):1201-9. PubMed ID: 10207172
[TBL] [Abstract][Full Text] [Related]
5. Comparing the relative role of perforin/granzyme versus Fas/Fas ligand cytotoxic pathways in CD8+ T cell-mediated insulin-dependent diabetes mellitus.
Kreuwel HT; Morgan DJ; Krahl T; Ko A; Sarvetnick N; Sherman LA
J Immunol; 1999 Oct; 163(8):4335-41. PubMed ID: 10510373
[TBL] [Abstract][Full Text] [Related]
6. IL-1alpha, IL-1beta, and IFN-gamma mark beta cells for Fas-dependent destruction by diabetogenic CD4(+) T lymphocytes.
Amrani A; Verdaguer J; Thiessen S; Bou S; Santamaria P
J Clin Invest; 2000 Feb; 105(4):459-68. PubMed ID: 10683375
[TBL] [Abstract][Full Text] [Related]
7. In vivo expression of perforin by CD8+ lymphocytes in autoimmune disease. Studies on spontaneous and adoptively transferred diabetes in nonobese diabetic mice.
Young LH; Peterson LB; Wicker LS; Persechini PM; Young JD
J Immunol; 1989 Dec; 143(12):3994-9. PubMed ID: 2480383
[TBL] [Abstract][Full Text] [Related]
8. TNF receptor 1-dependent beta cell toxicity as an effector pathway in autoimmune diabetes.
Kägi D; Ho A; Odermatt B; Zakarian A; Ohashi PS; Mak TW
J Immunol; 1999 Apr; 162(8):4598-605. PubMed ID: 10201999
[TBL] [Abstract][Full Text] [Related]
9. CD8 T cell clones from young nonobese diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 cells.
Wong FS; Visintin I; Wen L; Flavell RA; Janeway CA
J Exp Med; 1996 Jan; 183(1):67-76. PubMed ID: 8551245
[TBL] [Abstract][Full Text] [Related]
10. Transfer of autoimmune diabetes from diabetic NOD mice to NOD athymic nude mice: the roles of T cell subsets in the pathogenesis.
Matsumoto M; Yagi H; Kunimoto K; Kawaguchi J; Makino S; Harada M
Cell Immunol; 1993 Apr; 148(1):189-97. PubMed ID: 8098666
[TBL] [Abstract][Full Text] [Related]
11. Virus-induced autoimmune diabetes: most beta-cells die through inflammatory cytokines and not perforin from autoreactive (anti-viral) cytotoxic T-lymphocytes.
Seewaldt S; Thomas HE; Ejrnaes M; Christen U; Wolfe T; Rodrigo E; Coon B; Michelsen B; Kay TW; von Herrath MG
Diabetes; 2000 Nov; 49(11):1801-9. PubMed ID: 11078446
[TBL] [Abstract][Full Text] [Related]
12. Protection from type 1 diabetes in the face of high levels of activated autoaggressive lymphocytes in a viral transgenic mouse model crossed to the SV129 strain.
von Herrath MG; Wolfe T; Möhrle U; Coon B; Hughes A
Diabetes; 2001 Dec; 50(12):2700-8. PubMed ID: 11723052
[TBL] [Abstract][Full Text] [Related]
13. Acceleration of spontaneous diabetes in TCR-beta-transgenic nonobese diabetic mice by beta-cell cytotoxic CD8+ T cells expressing identical endogenous TCR-alpha chains.
Verdaguer J; Yoon JW; Anderson B; Averill N; Utsugi T; Park BJ; Santamaria P
J Immunol; 1996 Nov; 157(10):4726-35. PubMed ID: 8906855
[TBL] [Abstract][Full Text] [Related]
14. A mouse CD8 T cell-mediated acute autoimmune diabetes independent of the perforin and Fas cytotoxic pathways: possible role of membrane TNF.
Herrera PL; Harlan DM; Vassalli P
Proc Natl Acad Sci U S A; 2000 Jan; 97(1):279-84. PubMed ID: 10618409
[TBL] [Abstract][Full Text] [Related]
15. Cytotoxic T-cells from T-cell receptor transgenic NOD8.3 mice destroy beta-cells via the perforin and Fas pathways.
Dudek NL; Thomas HE; Mariana L; Sutherland RM; Allison J; Estella E; Angstetra E; Trapani JA; Santamaria P; Lew AM; Kay TW
Diabetes; 2006 Sep; 55(9):2412-8. PubMed ID: 16936188
[TBL] [Abstract][Full Text] [Related]
16. Perforin facilitates beta cell killing and regulates autoreactive CD8+ T-cell responses to antigen in mouse models of type 1 diabetes.
Trivedi P; Graham KL; Krishnamurthy B; Fynch S; Slattery RM; Kay TW; Thomas HE
Immunol Cell Biol; 2016 Apr; 94(4):334-41. PubMed ID: 26446877
[TBL] [Abstract][Full Text] [Related]
17. Granzyme B is dispensable in the development of diabetes in non-obese diabetic mice.
Mollah ZU; Graham KL; Krishnamurthy B; Trivedi P; Brodnicki TC; Trapani JA; Kay TW; Thomas HE
PLoS One; 2012; 7(7):e40357. PubMed ID: 22792290
[TBL] [Abstract][Full Text] [Related]
18. alpha/beta-T cell receptor (TCR)+CD4-CD8- (NKT) thymocytes prevent insulin-dependent diabetes mellitus in nonobese diabetic (NOD)/Lt mice by the influence of interleukin (IL)-4 and/or IL-10.
Hammond KJ; Poulton LD; Palmisano LJ; Silveira PA; Godfrey DI; Baxter AG
J Exp Med; 1998 Apr; 187(7):1047-56. PubMed ID: 9529321
[TBL] [Abstract][Full Text] [Related]
19. Abrogation of autoimmune diabetes in nonobese diabetic mice and protection against effector lymphocytes by transgenic paracrine TGF-beta1.
Moritani M; Yoshimoto K; Wong SF; Tanaka C; Yamaoka T; Sano T; Komagata Y; Miyazaki J; Kikutani H; Itakura M
J Clin Invest; 1998 Aug; 102(3):499-506. PubMed ID: 9691086
[TBL] [Abstract][Full Text] [Related]
20. Perforin/Fas-ligand double deficiency is associated with macrophage expansion and severe pancreatitis.
Spielman J; Lee RK; Podack ER
J Immunol; 1998 Dec; 161(12):7063-70. PubMed ID: 9862744
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]