These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

261 related articles for article (PubMed ID: 9316822)

  • 1. Time course of alpha-fluorinated valproic acid in mouse brain and serum and its effect on synaptosomal gamma-aminobutyric acid levels in comparison to valproic acid.
    Tang W; Palaty J; Abbott FS
    J Pharmacol Exp Ther; 1997 Sep; 282(3):1163-72. PubMed ID: 9316822
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Valproic acid: brain and plasma levels of the drug and its metabolites, anticonvulsant effects and gamma-aminobutyric acid (GABA) metabolism in the mouse.
    Nau H; Löscher W
    J Pharmacol Exp Ther; 1982 Mar; 220(3):654-9. PubMed ID: 6801254
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hydroxamic acid and fluorinated derivatives of valproic acid: anticonvulsant activity, neurotoxicity and teratogenicity.
    Gravemann U; Volland J; Nau H
    Neurotoxicol Teratol; 2008; 30(5):390-4. PubMed ID: 18455366
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A comparative investigation of 2-propyl-4-pentenoic acid (4-ene VPA) and its alpha-fluorinated analogue: phase II metabolism and pharmacokinetics.
    Tang W; Abbott FS
    Drug Metab Dispos; 1997 Feb; 25(2):219-27. PubMed ID: 9029053
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Comparison of the pharmacological and biochemical profiles of valproic acid (VPA) and its cerebral metabolite (2-en-VPA) after oral administration in mice.
    Keane PE; Simiand J; Morre M
    Methods Find Exp Clin Pharmacol; 1985 Feb; 7(2):83-6. PubMed ID: 2859407
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Disposition of valpromide, valproic acid, and valnoctamide in the brain, liver, plasma, and urine of rats.
    Blotnik S; Bergman F; Bialer M
    Drug Metab Dispos; 1996 May; 24(5):560-4. PubMed ID: 8723737
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Valproic acid in amygdala-kindled rats: alterations in anticonvulsant efficacy, adverse effects and drug and metabolite levels in various brain regions during chronic treatment.
    Löscher W; Fisher JE; Nau H; Hönack D
    J Pharmacol Exp Ther; 1989 Sep; 250(3):1067-78. PubMed ID: 2506334
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Valproic acid: metabolite concentrations in plasma and brain, anticonvulsant activity, and effects on GABA metabolism during subacute treatment in mice.
    Löscher W; Nau H
    Arch Int Pharmacodyn Ther; 1982 May; 257(1):20-31. PubMed ID: 6810778
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Distribution of valproic acid and its metabolites in various brain areas of dogs and rats after acute and prolonged treatment.
    Löscher W; Nau H
    J Pharmacol Exp Ther; 1983 Sep; 226(3):845-54. PubMed ID: 6411902
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Chemical and immunochemical comparison of protein adduct formation of four carboxylate drugs in rat liver and plasma.
    Bailey MJ; Dickinson RG
    Chem Res Toxicol; 1996; 9(3):659-66. PubMed ID: 8728513
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Alpha-fluoro-2,2,3,3-tetramethylcyclopropanecarboxamide, a novel potent anticonvulsant derivative of a cyclic analogue of valproic acid.
    Pessah N; Bialer M; Wlodarczyk B; Finnell RH; Yagen B
    J Med Chem; 2009 Apr; 52(8):2233-42. PubMed ID: 19296679
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Role of oxidative metabolism in the effect of valproic acid on markers of cell viability, necrosis, and oxidative stress in sandwich-cultured rat hepatocytes.
    Kiang TK; Teng XW; Karagiozov S; Surendradoss J; Chang TK; Abbott FS
    Toxicol Sci; 2010 Dec; 118(2):501-9. PubMed ID: 20861068
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Fluorinated analogues as mechanistic probes in valproic acid hepatotoxicity: hepatic microvesicular steatosis and glutathione status.
    Tang W; Borel AG; Fujimiya T; Abbott FS
    Chem Res Toxicol; 1995; 8(5):671-82. PubMed ID: 7548749
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Preliminary evaluation of the anticonvulsant activity of a valproic acid analog: N-(2-propylpentanoyl) urea.
    Tantisira B; Tantisira MH; Patarapanich C; Sooksawate T; Chunngam T
    Res Commun Mol Pathol Pharmacol; 1997 Aug; 97(2):151-64. PubMed ID: 9344228
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Valproic acid I: time course of lipid peroxidation biomarkers, liver toxicity, and valproic acid metabolite levels in rats.
    Tong V; Teng XW; Chang TK; Abbott FS
    Toxicol Sci; 2005 Aug; 86(2):427-35. PubMed ID: 15858223
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pharmacokinetic and pharmacodynamic analysis of (E)-2-ene valproyl derivatives of glycine and valproyl derivatives of nipecotic acid.
    Bialer M; Kadry B; Abdul-Hai A; Haj-Yehia A; Sterling J; Herzig Y; Shirvan M
    Biopharm Drug Dispos; 1996 Oct; 17(7):565-75. PubMed ID: 8894115
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dose-dependent pharmacokinetics and metabolism of valproic acid in newborn lambs and adult sheep.
    Wong H; Rurak DW; Kumar S; Kwan E; Abbott FS; Riggs KW
    Drug Metab Dispos; 2001 May; 29(5):664-75. PubMed ID: 11302932
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tetramethylcyclopropyl analogue of the leading antiepileptic drug, valproic acid: evaluation of the teratogenic effects of its amide derivatives in NMRI mice.
    Okada A; Onishi Y; Yagen B; Shimshoni JA; Kaufmann D; Bialer M; Fujiwara M
    Birth Defects Res A Clin Mol Teratol; 2008 Sep; 82(9):610-21. PubMed ID: 18671279
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ontogeny of valproic acid disposition and metabolism: a developmental study in postnatal lambs and adult sheep.
    Wong H; Kumar S; Rurak DW; Kwan E; Abbott FS; Riggs KW
    Drug Metab Dispos; 2000 Aug; 28(8):912-9. PubMed ID: 10901700
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Transfer of valproic acid and its main active unsaturated metabolite to the gestational tissue: correlation with neural tube defect formation in the mouse.
    Nau H
    Teratology; 1986 Feb; 33(1):21-7. PubMed ID: 3090732
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.