348 related articles for article (PubMed ID: 9321934)
1. From indomethacin to a selective COX-2 inhibitor. Development of indolalkanoic acids as potent and selective cyclooxygenase-2 inhibitors.
Lau CK; Black WC; Belley M; Chan C; Charleson S; Denis D; Gauthier JY; Gordon R; Guay D; Hamel P; Kargman S; Leblanc Y; Mancini J; Ouellet M; Percival D; Prasit P; Roy P; Skorey K; Tagari P; Vickers P; Wong E
Adv Exp Med Biol; 1997; 407():73-8. PubMed ID: 9321934
[No Abstract] [Full Text] [Related]
2. Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX-2 inhibitor.
Riendeau D; Percival MD; Boyce S; Brideau C; Charleson S; Cromlish W; Ethier D; Evans J; Falgueyret JP; Ford-Hutchinson AW; Gordon R; Greig G; Gresser M; Guay J; Kargman S; Léger S; Mancini JA; O'Neill G; Ouellet M; Rodger IW; Thérien M; Wang Z; Webb JK; Wong E; Chan CC
Br J Pharmacol; 1997 May; 121(1):105-17. PubMed ID: 9146894
[TBL] [Abstract][Full Text] [Related]
3. Selective cyclooxygenase-2 inhibitors as potential therapeutic agents for inflammatory diseases.
Chan CC; Rodger IW
Adv Exp Med Biol; 1997; 407():157-61. PubMed ID: 9321947
[No Abstract] [Full Text] [Related]
4. Thiazole analogues of the NSAID indomethacin as selective COX-2 inhibitors.
Woods KW; McCroskey RW; Michaelides MR; Wada CK; Hulkower KI; Bell RL
Bioorg Med Chem Lett; 2001 May; 11(10):1325-8. PubMed ID: 11392547
[TBL] [Abstract][Full Text] [Related]
5. Synthesis, structure-activity relationships, and in vivo evaluations of substituted di-tert-butylphenols as a novel class of potent, selective, and orally active cyclooxygenase-2 inhibitors. 1. Thiazolone and oxazolone series.
Song Y; Connor DT; Doubleday R; Sorenson RJ; Sercel AD; Unangst PC; Roth BD; Gilbertsen RB; Chan K; Schrier DJ; Guglietta A; Bornemeier DA; Dyer RD
J Med Chem; 1999 Apr; 42(7):1151-60. PubMed ID: 10197959
[TBL] [Abstract][Full Text] [Related]
6. Synthesis, structure-activity relationships, and in vivo evaluations of substituted di-tert-butylphenols as a novel class of potent, selective, and orally active cyclooxygenase-2 inhibitors. 2. 1,3,4- and 1,2,4-thiadiazole series.
Song Y; Connor DT; Sercel AD; Sorenson RJ; Doubleday R; Unangst PC; Roth BD; Beylin VG; Gilbertsen RB; Chan K; Schrier DJ; Guglietta A; Bornemeier DA; Dyer RD
J Med Chem; 1999 Apr; 42(7):1161-9. PubMed ID: 10197960
[TBL] [Abstract][Full Text] [Related]
7. 1,2-Diarylpyrroles as potent and selective inhibitors of cyclooxygenase-2.
Khanna IK; Weier RM; Yu Y; Collins PW; Miyashiro JM; Koboldt CM; Veenhuizen AW; Currie JL; Seibert K; Isakson PC
J Med Chem; 1997 May; 40(11):1619-33. PubMed ID: 9171872
[TBL] [Abstract][Full Text] [Related]
8. 2-Pyridinyl-3-(4-methylsulfonyl)phenylpyridines: selective and orally active cyclooxygenase-2 inhibitors.
Friesen RW; Brideau C; Chan CC; Charleson S; Deschênes D; Dubé D; Ethier D; Fortin R; Gauthier JY; Girard Y; Gordon R; Greig GM; Riendeau D; Savoie C; Wang Z; Wong E; Visco D; Xu LJ; Young RN
Bioorg Med Chem Lett; 1998 Oct; 8(19):2777-82. PubMed ID: 9873621
[TBL] [Abstract][Full Text] [Related]
9. Ester and amide derivatives of the nonsteroidal antiinflammatory drug, indomethacin, as selective cyclooxygenase-2 inhibitors.
Kalgutkar AS; Marnett AB; Crews BC; Remmel RP; Marnett LJ
J Med Chem; 2000 Jul; 43(15):2860-70. PubMed ID: 10956194
[TBL] [Abstract][Full Text] [Related]
10. Antiinflammatory 2-benzyl-4-sulfonyl-4H-isoquinoline-1,3-diones: novel inhibitors of COX-2.
Lazer ES; Sorcek R; Cywin CL; Thome D; Possanza GJ; Graham AG; Churchill L
Bioorg Med Chem Lett; 1998 May; 8(10):1181-6. PubMed ID: 9871731
[TBL] [Abstract][Full Text] [Related]
11. Inducible cyclooxygenase may have anti-inflammatory properties.
Gilroy DW; Colville-Nash PR; Willis D; Chivers J; Paul-Clark MJ; Willoughby DA
Nat Med; 1999 Jun; 5(6):698-701. PubMed ID: 10371510
[TBL] [Abstract][Full Text] [Related]
12. 3,4-Diaryl-5-hydroxyfuranones: highly selective inhibitors of cyclooxygenase-2 with aqueous solubility.
Black WC; Brideau C; Chan CC; Charleson S; Cromlish W; Gordon R; Grimm EL; Hughes G; Leger S; Li CS; Riendeau D; Thérien M; Wang Z; Xu LJ; Prasit P
Bioorg Med Chem Lett; 2003 Mar; 13(6):1195-8. PubMed ID: 12643942
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and anti-inflammatory activity of alkyl/arylidene-2-aminobenzothiazoles and 1-benzothiazol-2-yl-3-chloro-4-substituted-azetidin-2-ones.
Khedekar PB; Bahekar RH; Chopade RS; Umathe SN; Rao AR; Bhusari KP
Arzneimittelforschung; 2003; 53(9):640-7. PubMed ID: 14558438
[TBL] [Abstract][Full Text] [Related]
14. [Cyclooxygenases, structure, biological functions and the role in inflammation processes].
Kotyla PJ; Sliwińska-Kotyla B; Kucharz EJ
Pol Arch Med Wewn; 2001 Oct; 106(4):963-6. PubMed ID: 11993417
[No Abstract] [Full Text] [Related]
15. COX-1 and COX-2 inhibition: current status and future perspective.
Greyn J; Lauwers MH; Vanlersberghe C; Camu F
Acta Anaesthesiol Belg; 1998; 49(3):175-83. PubMed ID: 9844704
[No Abstract] [Full Text] [Related]
16. 1,2-Diarylimidazoles as potent, cyclooxygenase-2 selective, and orally active antiinflammatory agents.
Khanna IK; Weier RM; Yu Y; Xu XD; Koszyk FJ; Collins PW; Koboldt CM; Veenhuizen AW; Perkins WE; Casler JJ; Masferrer JL; Zhang YY; Gregory SA; Seibert K; Isakson PC
J Med Chem; 1997 May; 40(11):1634-47. PubMed ID: 9171873
[TBL] [Abstract][Full Text] [Related]
17. 2,3-Diarylbenzopyran derivatives as a novel class of selective cyclooxygenase-2 inhibitors.
Hyup YH; Kwan JK; Kang SH; Noh MS; Ha JY; Kyu JK; Min KM; Hoon CH; Chung S
Bioorg Med Chem Lett; 2003 Feb; 13(3):413-7. PubMed ID: 12565941
[TBL] [Abstract][Full Text] [Related]
18. Pharmacology of a selective cyclooxygenase-2 inhibitor, L-745,337: a novel nonsteroidal anti-inflammatory agent with an ulcerogenic sparing effect in rat and nonhuman primate stomach.
Chan CC; Boyce S; Brideau C; Ford-Hutchinson AW; Gordon R; Guay D; Hill RG; Li CS; Mancini J; Penneton M
J Pharmacol Exp Ther; 1995 Sep; 274(3):1531-7. PubMed ID: 7562530
[TBL] [Abstract][Full Text] [Related]
19. 2,3-Diarylcyclopentenones as orally active, highly selective cyclooxygenase-2 inhibitors.
Black WC; Brideau C; Chan CC; Charleson S; Chauret N; Claveau D; Ethier D; Gordon R; Greig G; Guay J; Hughes G; Jolicoeur P; Leblanc Y; Nicoll-Griffith D; Ouimet N; Riendeau D; Visco D; Wang Z; Xu L; Prasit P
J Med Chem; 1999 Apr; 42(7):1274-81. PubMed ID: 10197970
[TBL] [Abstract][Full Text] [Related]
20. Effects of nimesulide, a preferential cyclooxygenase-2 inhibitor, on carrageenan-induced pleurisy and stress-induced gastric lesions in rats.
Nakatsugi S; Terada N; Yoshimura T; Horie Y; Furukawa M
Prostaglandins Leukot Essent Fatty Acids; 1996 Dec; 55(6):395-402. PubMed ID: 9014217
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
