154 related articles for article (PubMed ID: 9325271)
1. Low barrier hydrogen bond is absent in the catalytic triads in the ground state but Is present in a transition-state complex in the prolyl oligopeptidase family of serine proteases.
Kahyaoglu A; Haghjoo K; Guo F; Jordan F; Kettner C; Felföldi F; Polgár L
J Biol Chem; 1997 Oct; 272(41):25547-54. PubMed ID: 9325271
[TBL] [Abstract][Full Text] [Related]
2. Structures of prolyl oligopeptidase substrate/inhibitor complexes. Use of inhibitor binding for titration of the catalytic histidine residue.
Fülöp V; Szeltner Z; Renner V; Polgár L
J Biol Chem; 2001 Jan; 276(2):1262-6. PubMed ID: 11031266
[TBL] [Abstract][Full Text] [Related]
3. Prolyl oligopeptidase catalysis. Reactions with thiono substrates reveal substrate-induced conformational change to be the rate-limiting step.
Polgár L; Kollt E; Hollósi M
FEBS Lett; 1993 May; 322(3):227-30. PubMed ID: 8486154
[TBL] [Abstract][Full Text] [Related]
4. The prolyl oligopeptidase family.
Polgár L
Cell Mol Life Sci; 2002 Feb; 59(2):349-62. PubMed ID: 11915948
[TBL] [Abstract][Full Text] [Related]
5. Electrostatic effects and binding determinants in the catalysis of prolyl oligopeptidase. Site specific mutagenesis at the oxyanion binding site.
Szeltner Z; Rea D; Renner V; Fulop V; Polgar L
J Biol Chem; 2002 Nov; 277(45):42613-22. PubMed ID: 12202494
[TBL] [Abstract][Full Text] [Related]
6. Nitrogen-15 NMR spectroscopy of the catalytic-triad histidine of a serine protease in peptide boronic acid inhibitor complexes.
Bachovchin WW; Wong WY; Farr-Jones S; Shenvi AB; Kettner CA
Biochemistry; 1988 Oct; 27(20):7689-97. PubMed ID: 3207700
[TBL] [Abstract][Full Text] [Related]
7. The noncatalytic beta-propeller domain of prolyl oligopeptidase enhances the catalytic capability of the peptidase domain.
Szeltner Z; Renner V; Polgár L
J Biol Chem; 2000 May; 275(20):15000-5. PubMed ID: 10747969
[TBL] [Abstract][Full Text] [Related]
8. Cleavage of the Lys196-Ser197 bond of prolyl oligopeptidase: enhanced catalytic activity for one of the two active enzyme forms.
Polgár L; Patthy A
Biochemistry; 1992 Nov; 31(44):10769-73. PubMed ID: 1420194
[TBL] [Abstract][Full Text] [Related]
9. Low-barrier hydrogen bonding in molecular complexes analogous to histidine and aspartate in the catalytic triad of serine proteases.
Tobin JB; Whitt SA; Cassidy CS; Frey PA
Biochemistry; 1995 May; 34(21):6919-24. PubMed ID: 7766600
[TBL] [Abstract][Full Text] [Related]
10. Kinetic and mechanistic studies of prolyl oligopeptidase from the hyperthermophile Pyrococcus furiosus.
Harris MN; Madura JD; Ming LJ; Harwood VJ
J Biol Chem; 2001 Jun; 276(22):19310-7. PubMed ID: 11278687
[TBL] [Abstract][Full Text] [Related]
11. Short, strong hydrogen bonds at the active site of human acetylcholinesterase: proton NMR studies.
Massiah MA; Viragh C; Reddy PM; Kovach IM; Johnson J; Rosenberry TL; Mildvan AS
Biochemistry; 2001 May; 40(19):5682-90. PubMed ID: 11341833
[TBL] [Abstract][Full Text] [Related]
12. Substrate-dependent, non-hyperbolic kinetics of pig brain prolyl oligopeptidase and its tight binding inhibition by JTP-4819.
Venäläinen JI; Juvonen RO; Forsberg MM; Garcia-Horsman A; Poso A; Wallen EA; Gynther J; Männistö PT
Biochem Pharmacol; 2002 Aug; 64(3):463-71. PubMed ID: 12147298
[TBL] [Abstract][Full Text] [Related]
13. The PREPL A protein, a new member of the prolyl oligopeptidase family, lacking catalytic activity.
Szeltner Z; Alshafee I; Juhász T; Parvari R; Polgár L
Cell Mol Life Sci; 2005 Oct; 62(19-20):2376-81. PubMed ID: 16143824
[TBL] [Abstract][Full Text] [Related]
14. Unusual 1H NMR chemical shifts support (His) C(epsilon) 1...O==C H-bond: proposal for reaction-driven ring flip mechanism in serine protease catalysis.
Ash EL; Sudmeier JL; Day RM; Vincent M; Torchilin EV; Haddad KC; Bradshaw EM; Sanford DG; Bachovchin WW
Proc Natl Acad Sci U S A; 2000 Sep; 97(19):10371-6. PubMed ID: 10984533
[TBL] [Abstract][Full Text] [Related]
15. A low-barrier hydrogen bond in the catalytic triad of serine proteases? Theory versus experiment.
Ash EL; Sudmeier JL; De Fabo EC; Bachovchin WW
Science; 1997 Nov; 278(5340):1128-32. PubMed ID: 9353195
[TBL] [Abstract][Full Text] [Related]
16. Oligopeptidases, and the emergence of the prolyl oligopeptidase family.
Barrett AJ; Rawlings ND
Biol Chem Hoppe Seyler; 1992 Jul; 373(7):353-60. PubMed ID: 1515061
[TBL] [Abstract][Full Text] [Related]
17. Substrate-dependent competency of the catalytic triad of prolyl oligopeptidase.
Szeltner Z; Rea D; Juhász T; Renner V; Mucsi Z; Orosz G; Fülöp V; Polgár L
J Biol Chem; 2002 Nov; 277(47):44597-605. PubMed ID: 12228249
[TBL] [Abstract][Full Text] [Related]
18. A low-barrier hydrogen bond in the catalytic triad of serine proteases.
Frey PA; Whitt SA; Tobin JB
Science; 1994 Jun; 264(5167):1927-30. PubMed ID: 7661899
[TBL] [Abstract][Full Text] [Related]
19. Low-barrier hydrogen bonds and enzymatic catalysis.
Cleland WW
Arch Biochem Biophys; 2000 Oct; 382(1):1-5. PubMed ID: 11051090
[TBL] [Abstract][Full Text] [Related]
20. Electrostatic environment at the active site of prolyl oligopeptidase is highly influential during substrate binding.
Szeltner Z; Rea D; Renner V; Juliano L; Fülop V; Polgár L
J Biol Chem; 2003 Dec; 278(49):48786-93. PubMed ID: 14514675
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]