BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

204 related articles for article (PubMed ID: 9334372)

  • 1. Granule-mediated killing: pathways for granzyme B-initiated apoptosis.
    Talanian RV; Yang X; Turbov J; Seth P; Ghayur T; Casiano CA; Orth K; Froelich CJ
    J Exp Med; 1997 Oct; 186(8):1323-31. PubMed ID: 9334372
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Apoptosis induced by granzyme B-glycosaminoglycan complexes: implications for granule-mediated apoptosis in vivo.
    Galvin JP; Spaeny-Dekking LH; Wang B; Seth P; Hack CE; Froelich CJ
    J Immunol; 1999 May; 162(9):5345-50. PubMed ID: 10228010
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Granzyme B-mediated degradation of T-cell receptor zeta chain.
    Wieckowski E; Wang GQ; Gastman BR; Goldstein LA; Rabinowich H
    Cancer Res; 2002 Sep; 62(17):4884-9. PubMed ID: 12208735
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Granzyme B short-circuits the need for caspase 8 activity during granule-mediated cytotoxic T-lymphocyte killing by directly cleaving Bid.
    Barry M; Heibein JA; Pinkoski MJ; Lee SF; Moyer RW; Green DR; Bleackley RC
    Mol Cell Biol; 2000 Jun; 20(11):3781-94. PubMed ID: 10805722
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cytotoxic T lymphocyte-assisted suicide. Caspase 3 activation is primarily the result of the direct action of granzyme B.
    Atkinson EA; Barry M; Darmon AJ; Shostak I; Turner PC; Moyer RW; Bleackley RC
    J Biol Chem; 1998 Aug; 273(33):21261-6. PubMed ID: 9694885
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Granzyme B mimics apical caspases. Description of a unified pathway for trans-activation of executioner caspase-3 and -7.
    Yang X; Stennicke HR; Wang B; Green DR; Jänicke RU; Srinivasan A; Seth P; Salvesen GS; Froelich CJ
    J Biol Chem; 1998 Dec; 273(51):34278-83. PubMed ID: 9852092
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cleavage of FLICE (caspase-8) by granzyme B during cytotoxic T lymphocyte-induced apoptosis.
    Medema JP; Toes RE; Scaffidi C; Zheng TS; Flavell RA; Melief CJ; Peter ME; Offringa R; Krammer PH
    Eur J Immunol; 1997 Dec; 27(12):3492-8. PubMed ID: 9464839
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Direct cleavage of the human DNA fragmentation factor-45 by granzyme B induces caspase-activated DNase release and DNA fragmentation.
    Sharif-Askari E; Alam A; Rhéaume E; Beresford PJ; Scotto C; Sharma K; Lee D; DeWolf WE; Nuttall ME; Lieberman J; Sékaly RP
    EMBO J; 2001 Jun; 20(12):3101-13. PubMed ID: 11406587
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Bcl-2 expression in target cells leads to functional inhibition of caspase-3 protease family in human NK and lymphokine-activated killer cell granule-mediated apoptosis.
    Renvoizé C; Roger R; Moulian N; Bertoglio J; Bréard J
    J Immunol; 1997 Jul; 159(1):126-34. PubMed ID: 9200447
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Direct cleavage of ROCK II by granzyme B induces target cell membrane blebbing in a caspase-independent manner.
    Sebbagh M; Hamelin J; Bertoglio J; Solary E; Bréard J
    J Exp Med; 2005 Feb; 201(3):465-71. PubMed ID: 15699075
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The cytotoxic cell protease granzyme B initiates apoptosis in a cell-free system by proteolytic processing and activation of the ICE/CED-3 family protease, CPP32, via a novel two-step mechanism.
    Martin SJ; Amarante-Mendes GP; Shi L; Chuang TH; Casiano CA; O'Brien GA; Fitzgerald P; Tan EM; Bokoch GM; Greenberg AH; Green DR
    EMBO J; 1996 May; 15(10):2407-16. PubMed ID: 8665848
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Resistance to granzyme B-mediated cytochrome c release in Bak-deficient cells.
    Wang GQ; Wieckowski E; Goldstein LA; Gastman BR; Rabinovitz A; Gambotto A; Li S; Fang B; Yin XM; Rabinowich H
    J Exp Med; 2001 Nov; 194(9):1325-37. PubMed ID: 11696597
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Granule-derived granzyme B mediates the vulnerability of human neurons to T cell-induced neurotoxicity.
    Haile Y; Simmen KC; Pasichnyk D; Touret N; Simmen T; Lu JQ; Bleackley RC; Giuliani F
    J Immunol; 2011 Nov; 187(9):4861-72. PubMed ID: 21964027
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Caspase dependence of target cell damage induced by cytotoxic lymphocytes.
    Sarin A; Haddad EK; Henkart PA
    J Immunol; 1998 Sep; 161(6):2810-6. PubMed ID: 9743340
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Disruption of Mcl-1.Bim complex in granzyme B-mediated mitochondrial apoptosis.
    Han J; Goldstein LA; Gastman BR; Rabinovitz A; Rabinowich H
    J Biol Chem; 2005 Apr; 280(16):16383-92. PubMed ID: 15713684
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interaction of the nuclear localizing cytolytic granule serine protease granzyme B with importin alpha or beta: modulation by the serpin inhibitor PI-9.
    Blink EJ; Jiansheng Z; Hu W; Calanni ST; Trapani JA; Bird PI; Jans DA
    J Cell Biochem; 2005 Jun; 95(3):598-610. PubMed ID: 15791691
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Adenovirus L4-100K assembly protein is a granzyme B substrate that potently inhibits granzyme B-mediated cell death.
    Andrade F; Bull HG; Thornberry NA; Ketner GW; Casciola-Rosen LA; Rosen A
    Immunity; 2001 Jun; 14(6):751-61. PubMed ID: 11420045
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Targeted induction of apoptosis by chimeric granzyme B fusion proteins carrying antibody and growth factor domains for cell recognition.
    Dälken B; Giesübel U; Knauer SK; Wels WS
    Cell Death Differ; 2006 Apr; 13(4):576-85. PubMed ID: 16179940
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Granzyme B activates procaspase-3 which signals a mitochondrial amplification loop for maximal apoptosis.
    Metkar SS; Wang B; Ebbs ML; Kim JH; Lee YJ; Raja SM; Froelich CJ
    J Cell Biol; 2003 Mar; 160(6):875-85. PubMed ID: 12629051
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular ordering of the caspase activation cascade initiated by the cytotoxic T lymphocyte/natural killer (CTL/NK) protease granzyme B.
    Adrain C; Murphy BM; Martin SJ
    J Biol Chem; 2005 Feb; 280(6):4663-73. PubMed ID: 15569669
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.