These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
383 related articles for article (PubMed ID: 9336307)
1. The prediction of human pharmacokinetic parameters from preclinical and in vitro metabolism data. Obach RS; Baxter JG; Liston TE; Silber BM; Jones BC; MacIntyre F; Rance DJ; Wastall P J Pharmacol Exp Ther; 1997 Oct; 283(1):46-58. PubMed ID: 9336307 [TBL] [Abstract][Full Text] [Related]
2. Prediction of human pharmacokinetics from preclinical information: comparative accuracy of quantitative prediction approaches. Hosea NA; Collard WT; Cole S; Maurer TS; Fang RX; Jones H; Kakar SM; Nakai Y; Smith BJ; Webster R; Beaumont K J Clin Pharmacol; 2009 May; 49(5):513-33. PubMed ID: 19299532 [TBL] [Abstract][Full Text] [Related]
3. A comprehensive quantitative and qualitative evaluation of extrapolation of intravenous pharmacokinetic parameters from rat, dog, and monkey to humans. I. Clearance. Ward KW; Smith BR Drug Metab Dispos; 2004 Jun; 32(6):603-11. PubMed ID: 15155551 [TBL] [Abstract][Full Text] [Related]
4. The prediction of human clearance from hepatic microsomal metabolism data. Obach RS Curr Opin Drug Discov Devel; 2001 Jan; 4(1):36-44. PubMed ID: 11727321 [TBL] [Abstract][Full Text] [Related]
5. Extrapolation of preclinical pharmacokinetics and molecular feature analysis of "discovery-like" molecules to predict human pharmacokinetics. Evans CA; Jolivette LJ; Nagilla R; Ward KW Drug Metab Dispos; 2006 Jul; 34(7):1255-65. PubMed ID: 16621936 [TBL] [Abstract][Full Text] [Related]
6. Animal pharmacokinetics of the tumor necrosis factor receptor-immunoglobulin fusion protein lenercept and their extrapolation to humans. Richter WF; Gallati H; Schiller CD Drug Metab Dispos; 1999 Jan; 27(1):21-5. PubMed ID: 9884305 [TBL] [Abstract][Full Text] [Related]
7. Preclinical pharmacokinetics of a novel HIV-1 attachment inhibitor BMS-378806 and prediction of its human pharmacokinetics. Yang Z; Zadjura L; D'Arienzo C; Marino A; Santone K; Klunk L; Greene D; Lin PF; Colonno R; Wang T; Meanwell N; Hansel S Biopharm Drug Dispos; 2005 Dec; 26(9):387-402. PubMed ID: 16142720 [TBL] [Abstract][Full Text] [Related]
8. Prediction of human clearance of twenty-nine drugs from hepatic microsomal intrinsic clearance data: An examination of in vitro half-life approach and nonspecific binding to microsomes. Obach RS Drug Metab Dispos; 1999 Nov; 27(11):1350-9. PubMed ID: 10534321 [TBL] [Abstract][Full Text] [Related]
9. Prediction of human hepatic clearance from in vivo animal experiments and in vitro metabolic studies with liver microsomes from animals and humans. Naritomi Y; Terashita S; Kimura S; Suzuki A; Kagayama A; Sugiyama Y Drug Metab Dispos; 2001 Oct; 29(10):1316-24. PubMed ID: 11560875 [TBL] [Abstract][Full Text] [Related]
10. Prediction of human oral pharmacokinetics using nonclinical data: examples involving four proprietary compounds. Fura A; Vyas V; Humphreys W; Chimalokonda A; Rodrigues D Biopharm Drug Dispos; 2008 Nov; 29(8):455-68. PubMed ID: 18989850 [TBL] [Abstract][Full Text] [Related]
11. [Advances and related issues in the use of in vitro methods to predict metabolic clearance rate of new drugs]. Zhang Q; Wang GJ Yao Xue Xue Bao; 2007 Oct; 42(10):1023-8. PubMed ID: 18229605 [TBL] [Abstract][Full Text] [Related]
12. Prediction of human pharmacokinetics--evaluation of methods for prediction of hepatic metabolic clearance. Fagerholm U J Pharm Pharmacol; 2007 Jun; 59(6):803-28. PubMed ID: 17637173 [TBL] [Abstract][Full Text] [Related]
13. Prediction of human pharmacokinetics using physiologically based modeling: a retrospective analysis of 26 clinically tested drugs. De Buck SS; Sinha VK; Fenu LA; Nijsen MJ; Mackie CE; Gilissen RA Drug Metab Dispos; 2007 Oct; 35(10):1766-80. PubMed ID: 17620347 [TBL] [Abstract][Full Text] [Related]
14. Preclinical pharmacokinetics and metabolism of 6-(4-(2,5-difluorophenyl)oxazol-5-yl)-3-isopropyl-[1,2,4]-triazolo[4,3-a]pyridine, a novel and selective p38alpha inhibitor: identification of an active metabolite in preclinical species and human liver microsomes. Kalgutkar AS; Hatch HL; Kosea F; Nguyen HT; Choo EF; McClure KF; Taylor TJ; Henne KR; Kuperman AV; Dombroski MA; Letavic MA Biopharm Drug Dispos; 2006 Nov; 27(8):371-86. PubMed ID: 16944451 [TBL] [Abstract][Full Text] [Related]
15. Predicting human pharmacokinetics from preclinical data. Poggesi I Curr Opin Drug Discov Devel; 2004 Jan; 7(1):100-11. PubMed ID: 14982153 [TBL] [Abstract][Full Text] [Related]
16. Does human pharmacokinetic prediction add significant value to compound selection in drug discovery research? Beaumont K; Smith DA Curr Opin Drug Discov Devel; 2009 Jan; 12(1):61-71. PubMed ID: 19152214 [TBL] [Abstract][Full Text] [Related]
17. A comprehensive quantitative and qualitative evaluation of extrapolation of intravenous pharmacokinetic parameters from rat, dog, and monkey to humans. II. Volume of distribution and mean residence time. Ward KW; Smith BR Drug Metab Dispos; 2004 Jun; 32(6):612-9. PubMed ID: 15155552 [TBL] [Abstract][Full Text] [Related]
18. Allometric relationships between the pharmacokinetics of propofol in rats, children and adults. Knibbe CA; Zuideveld KP; Aarts LP; Kuks PF; Danhof M Br J Clin Pharmacol; 2005 Jun; 59(6):705-11. PubMed ID: 15948935 [TBL] [Abstract][Full Text] [Related]
19. Comparison of prediction methods for in vivo clearance of (S,S)-3-[3-(methylsulfonyl)phenyl]-1-propylpiperidine hydrochloride, a dopamine D2 receptor antagonist, in humans. Yamazaki S; Toth LN; Black ML; Duncan JN Drug Metab Dispos; 2004 Apr; 32(4):398-404. PubMed ID: 15039292 [TBL] [Abstract][Full Text] [Related]
20. Interspecies allometric scaling. Part I: prediction of clearance in large animals. Mahmood I; Martinez M; Hunter RP J Vet Pharmacol Ther; 2006 Oct; 29(5):415-23. PubMed ID: 16958787 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]