These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

126 related articles for article (PubMed ID: 9342312)

  • 1. On roads not taken in the evolution of protein catalysts: antibody steroid isomerases that use an enamine mechanism.
    Lin CH; Hoffman TZ; Wirsching P; Barbas CF; Janda KD; Lerner RA
    Proc Natl Acad Sci U S A; 1997 Oct; 94(22):11773-6. PubMed ID: 9342312
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular dynamics and quantum chemical studies on the catalytic mechanism of Delta5-3-ketosteroid isomerase: the catalytic diad versus the cooperative hydrogen bond mechanism.
    Park H; Merz KM
    J Am Chem Soc; 2003 Jan; 125(4):901-11. PubMed ID: 12537487
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Enzymatic mechanisms for catalysis of enolization: ketosteroid isomerase.
    Pollack RM
    Bioorg Chem; 2004 Oct; 32(5):341-53. PubMed ID: 15381400
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The conserved cis-Pro39 residue plays a crucial role in the proper positioning of the catalytic base Asp38 in ketosteroid isomerase from Comamonas testosteroni.
    Nam GH; Cha SS; Yun YS; Oh YH; Hong BH; Lee HS; Choi KY
    Biochem J; 2003 Oct; 375(Pt 2):297-305. PubMed ID: 12852789
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Temperature effects on the catalytic activity of the D38E mutant of 3-oxo-Delta5-steroid isomerase: favorable enthalpies and entropies of activation relative to the nonenzymatic reaction catalyzed by acetate ion.
    Houck WJ; Pollack RM
    J Am Chem Soc; 2004 Dec; 126(50):16416-25. PubMed ID: 15600343
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Energetics of 3-oxo-delta 5-steroid isomerase: source of the catalytic power of the enzyme.
    Hawkinson DC; Eames TC; Pollack RM
    Biochemistry; 1991 Nov; 30(45):10849-58. PubMed ID: 1932007
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Insights into the catalytic mechanism and active-site environment of Comamonas testosteroni delta 5-3-ketosteroid isomerase as revealed by site-directed mutagenesis of the catalytic base aspartate-38.
    Holman CM; Benisek WF
    Biochemistry; 1995 Oct; 34(43):14245-53. PubMed ID: 7578024
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Kinetic competence of an externally generated dienol intermediate with steroid isomerase.
    Hawkinson DC; Eames TC; Pollack RM
    Biochemistry; 1991 Jul; 30(28):6956-64. PubMed ID: 1676914
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Experimental evidence for enzyme-enhanced coupled motion/quantum mechanical hydrogen tunneling by ketosteroid isomerase.
    Wilde TC; Blotny G; Pollack RM
    J Am Chem Soc; 2008 May; 130(20):6577-85. PubMed ID: 18426205
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A theoretical model of the catalytic mechanism of the Delta5-3-ketosteroid isomerase reaction.
    Sharma K; Vázquez-Ramírez R; Kubli-Garfias C
    Steroids; 2006 Jul; 71(7):549-57. PubMed ID: 16620897
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Role of conserved Met112 residue in the catalytic activity and stability of ketosteroid isomerase.
    Cha HJ; Jang do S; Jeong JH; Hong BH; Yun YS; Shin EJ; Choi KY
    Biochim Biophys Acta; 2016 Oct; 1864(10):1322-7. PubMed ID: 27375051
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Kemp Eliminase Activity of Ketosteroid Isomerase.
    Lamba V; Sanchez E; Fanning LR; Howe K; Alvarez MA; Herschlag D; Forconi M
    Biochemistry; 2017 Jan; 56(4):582-591. PubMed ID: 28045505
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Crystal structure and enzyme mechanism of Delta 5-3-ketosteroid isomerase from Pseudomonas testosteroni.
    Cho HS; Choi G; Choi KY; Oh BH
    Biochemistry; 1998 Jun; 37(23):8325-30. PubMed ID: 9622484
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Electrophilic assistance by Asp-99 of 3-oxo-Delta 5-steroid isomerase.
    Thornburg LD; Hénot F; Bash DP; Hawkinson DC; Bartel SD; Pollack RM
    Biochemistry; 1998 Jul; 37(29):10499-506. PubMed ID: 9671521
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evaluation of the energetics of the concerted acid-base mechanism in enzymatic catalysis: the case of ketosteroid isomerase.
    Fried SD; Boxer SG
    J Phys Chem B; 2012 Jan; 116(1):690-7. PubMed ID: 22148842
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Efficient aldolase catalytic antibodies that use the enamine mechanism of natural enzymes.
    Wagner J; Lerner RA; Barbas CF
    Science; 1995 Dec; 270(5243):1797-800. PubMed ID: 8525368
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Small exterior hydrophobic cluster contributes to conformational stability and steroid binding in ketosteroid isomerase from Pseudomonas putida biotype B.
    Yun YS; Nam GH; Kim YG; Oh BH; Choi KY
    FEBS J; 2005 Apr; 272(8):1999-2011. PubMed ID: 15819891
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structure and enzymology of Delta5-3-ketosteroid isomerase.
    Ha NC; Choi G; Choi KY; Oh BH
    Curr Opin Struct Biol; 2001 Dec; 11(6):674-8. PubMed ID: 11751047
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Extreme Catalytic Power of Ketosteroid Isomerase Related to the Reversal of Proton Dislocations in Hydrogen-Bond Network.
    Kędzierski P; Zaczkowska M; Sokalski WA
    J Phys Chem B; 2020 May; 124(18):3661-3666. PubMed ID: 32293890
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Extreme electric fields power catalysis in the active site of ketosteroid isomerase.
    Fried SD; Bagchi S; Boxer SG
    Science; 2014 Dec; 346(6216):1510-4. PubMed ID: 25525245
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.