BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

529 related articles for article (PubMed ID: 9343371)

  • 1. The role of NAD(P)H:quinone oxidoreductase in quinone-mediated p21 induction in human colon carcinoma cells.
    Qiu XB; Cadenas E
    Arch Biochem Biophys; 1997 Oct; 346(2):241-51. PubMed ID: 9343371
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Induction of p21 mediated by reactive oxygen species formed during the metabolism of aziridinylbenzoquinones by HCT116 cells.
    Qiu X; Forman HJ; Schönthal AH; Cadenas E
    J Biol Chem; 1996 Dec; 271(50):31915-21. PubMed ID: 8943236
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Relationship between DT-diaphorase-mediated metabolism of a series of aziridinylbenzoquinones and DNA damage and cytotoxicity.
    Gibson NW; Hartley JA; Butler J; Siegel D; Ross D
    Mol Pharmacol; 1992 Sep; 42(3):531-6. PubMed ID: 1406604
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Metabolism of diaziquone by NAD(P)H:(quinone acceptor) oxidoreductase (DT-diaphorase): role in diaziquone-induced DNA damage and cytotoxicity in human colon carcinoma cells.
    Siegel D; Gibson NW; Preusch PC; Ross D
    Cancer Res; 1990 Nov; 50(22):7293-300. PubMed ID: 2121335
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Role of p53 in aziridinylbenzoquinone-induced p21waf1 expression.
    Wu RC; Hohenstein A; Park JM; Qiu X; Mueller S; Cadenas E; Schönthal AH
    Oncogene; 1998 Jul; 17(3):357-65. PubMed ID: 9690517
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Induction of p53 by the concerted actions of aziridine and quinone moieties of diaziquone.
    Ngo EO; Nutter LM; Sura T; Gutierrez PL
    Chem Res Toxicol; 1998 Apr; 11(4):360-8. PubMed ID: 9548807
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The reductive metabolism of diaziquone (AZQ) in the S9 fraction of MCF-7 cells: free radical formation and NAD(P)H: quinone-acceptor oxidoreductase (DT-diaphorase) activity.
    Fisher GR; Gutierrez PL
    Free Radic Biol Med; 1991; 10(6):359-70. PubMed ID: 1654286
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The reductive activation of the antitumor drug RH1 to its semiquinone free radical by NADPH cytochrome P450 reductase and by HCT116 human colon cancer cells.
    Hasinoff BB; Begleiter A
    Free Radic Res; 2006 Sep; 40(9):974-8. PubMed ID: 17015278
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The histone deacetylase inhibitor MS-275 promotes differentiation or apoptosis in human leukemia cells through a process regulated by generation of reactive oxygen species and induction of p21CIP1/WAF1 1.
    Rosato RR; Almenara JA; Grant S
    Cancer Res; 2003 Jul; 63(13):3637-45. PubMed ID: 12839953
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A new screening system for NAD(P)H:quinone oxidoreductase (NQO1)-directed antitumor quinones: identification of a new aziridinylbenzoquinone, RH1, as a NQO1-directed antitumor agent.
    Winski SL; Hargreaves RH; Butler J; Ross D
    Clin Cancer Res; 1998 Dec; 4(12):3083-8. PubMed ID: 9865924
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mapping of DNA alkylation sites induced by aziridinylbenzoquinones in human cells by ligation-mediated polymerase chain reaction.
    Lee CS; Pfeifer GP; Gibson NW
    Cancer Res; 1994 Apr; 54(7):1622-6. PubMed ID: 8137269
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The effect of functional groups on reduction and activation of quinone bioreductive agents by DT-diaphorase.
    Fourie J; Oleschuk CJ; Guziec F; Guziec L; Fiterman DJ; Monterrosa C; Begleiter A
    Cancer Chemother Pharmacol; 2002 Feb; 49(2):101-10. PubMed ID: 11862423
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cellular kinetics of induction by oltipraz and its keto derivative of detoxication enzymes in human colon adenocarcinoma cells.
    O'Dwyer PJ; Clayton M; Halbherr T; Myers CB; Yao Ks
    Clin Cancer Res; 1997 May; 3(5):783-91. PubMed ID: 9815750
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cellular density and cell type are the key factors in growth inhibition induced by 2,5bis [1-aziridinyl]-1,4 benzoquinone (DZQ).
    Córdoba-Pedregosa Mdel C; Villalba JM; González-Aragón D; Bello RI; Alcaín FJ
    Anticancer Res; 2006; 26(5A):3535-40. PubMed ID: 17094478
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Free radical formation and DNA strand breakage during metabolism of diaziquone by NAD(P)H quinone-acceptor oxidoreductase (DT-diaphorase) and NADPH cytochrome c reductase.
    Fisher GR; Gutierrez PL
    Free Radic Biol Med; 1991; 11(6):597-607. PubMed ID: 1663902
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Polyamine depletion in human melanoma cells leads to G1 arrest associated with induction of p21WAF1/CIP1/SDI1, changes in the expression of p21-regulated genes, and a senescence-like phenotype.
    Kramer DL; Chang BD; Chen Y; Diegelman P; Alm K; Black AR; Roninson IB; Porter CW
    Cancer Res; 2001 Nov; 61(21):7754-62. PubMed ID: 11691789
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Roles of histidine-194, aspartate-163, and a glycine-rich sequence of NAD(P)H:quinone oxidoreductase in the interaction with nicotinamide coenzymes.
    Cui K; Ma Q; Lu AY; Yang CS
    Arch Biochem Biophys; 1995 Nov; 323(2):265-73. PubMed ID: 7487087
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Polyamine analogue induction of the p53-p21WAF1/CIP1-Rb pathway and G1 arrest in human melanoma cells.
    Kramer DL; Vujcic S; Diegelman P; Alderfer J; Miller JT; Black JD; Bergeron RJ; Porter CW
    Cancer Res; 1999 Mar; 59(6):1278-86. PubMed ID: 10096560
    [TBL] [Abstract][Full Text] [Related]  

  • 19. NAD(P)H:quinone oxidoreductase gene expression in human colon carcinoma cells: characterization of a mutation which modulates DT-diaphorase activity and mitomycin sensitivity.
    Traver RD; Horikoshi T; Danenberg KD; Stadlbauer TH; Danenberg PV; Ross D; Gibson NW
    Cancer Res; 1992 Feb; 52(4):797-802. PubMed ID: 1737339
    [TBL] [Abstract][Full Text] [Related]  

  • 20. DNA strand scission by polycyclic aromatic hydrocarbon o-quinones: role of reactive oxygen species, Cu(II)/Cu(I) redox cycling, and o-semiquinone anion radicals,
    Flowers L; Ohnishi ST; Penning TM
    Biochemistry; 1997 Jul; 36(28):8640-8. PubMed ID: 9214311
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 27.