264 related articles for article (PubMed ID: 9345060)
1. Diphtheria toxin fused to granulocyte-macrophage colony-stimulating factor eliminates acute myeloid leukemia cells with the potential to initiate leukemia in immunodeficient mice, but spares normal hemopoietic stem cells.
Terpstra W; Rozemuller H; Breems DA; Rombouts EJ; Prins A; FitzGerald DJ; Kreitman RJ; Wielenga JJ; Ploemacher RE; Löwenberg B; Hagenbeek A; Martens AC
Blood; 1997 Nov; 90(9):3735-42. PubMed ID: 9345060
[TBL] [Abstract][Full Text] [Related]
2. Variable cytotoxicity of diphtheria toxin 388-granulocyte-macrophage colony-stimulating factor fusion protein for acute myelogenous leukemia stem cells.
Feuring-Buske M; Frankel A; Gerhard B; Hogge D
Exp Hematol; 2000 Dec; 28(12):1390-400. PubMed ID: 11146161
[TBL] [Abstract][Full Text] [Related]
3. Diphtheria toxin fused to granulocyte-macrophage colony-stimulating factor is toxic to blasts from patients with juvenile myelomonocytic leukemia and chronic myelomonocytic leukemia.
Frankel AE; Lilly M; Kreitman R; Hogge D; Beran M; Freedman MH; Emanuel PD; McLain C; Hall P; Tagge E; Berger M; Eaves C
Blood; 1998 Dec; 92(11):4279-86. PubMed ID: 9834234
[TBL] [Abstract][Full Text] [Related]
4. Malignant progenitors from patients with acute myelogenous leukemia are sensitive to a diphtheria toxin-granulocyte-macrophage colony-stimulating factor fusion protein.
Hogge DE; Willman CL; Kreitman RJ; Berger M; Hall PD; Kopecky KJ; McLain C; Tagge EP; Eaves CJ; Frankel AE
Blood; 1998 Jul; 92(2):589-95. PubMed ID: 9657759
[TBL] [Abstract][Full Text] [Related]
5. A recombinant fusion toxin targeted to the granulocyte-macrophage colony-stimulating factor receptor.
Bendel AE; Shao Y; Davies SM; Warman B; Yang CH; Waddick KG; Uckun FM; Perentesis JP
Leuk Lymphoma; 1997 Apr; 25(3-4):257-70. PubMed ID: 9168436
[TBL] [Abstract][Full Text] [Related]
6. A diphtheria toxin-interleukin 3 fusion protein is cytotoxic to primitive acute myeloid leukemia progenitors but spares normal progenitors.
Feuring-Buske M; Frankel AE; Alexander RL; Gerhard B; Hogge DE
Cancer Res; 2002 Mar; 62(6):1730-6. PubMed ID: 11912147
[TBL] [Abstract][Full Text] [Related]
7. GM-CSF receptor targeted treatment of primary AML in SCID mice using Diphtheria toxin fused to huGM-CSF.
Rozemuller H; Terpstra W; Rombouts EJ; Lawler M; Byrne C; FitzGerald DJ; Kreitman RJ; Wielenga JJ; Löwenberg B; Touw IP; Hagenbeek A; Martens AC
Leukemia; 1998 Dec; 12(12):1962-70. PubMed ID: 9844926
[TBL] [Abstract][Full Text] [Related]
8. A murine cytokine fusion toxin specifically targeting the murine granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor on normal committed bone marrow progenitor cells and GM-CSF-dependent tumor cells.
Chan CH; Blazar BR; Eide CR; Kreitman RJ; Vallera DA
Blood; 1995 Oct; 86(7):2732-40. PubMed ID: 7670112
[TBL] [Abstract][Full Text] [Related]
9. Fluorouracil selectively spares acute myeloid leukemia cells with long-term growth abilities in immunodeficient mice and in culture.
Terpstra W; Ploemacher RE; Prins A; van Lom K; Pouwels K; Wognum AW; Wagemaker G; Löwenberg B; Wielenga JJ
Blood; 1996 Sep; 88(6):1944-50. PubMed ID: 8822911
[TBL] [Abstract][Full Text] [Related]
10. In vivo targeting of leukemic cells using diphtheria toxin fused to murine GM-CSF.
Rozemuller H; Rombouts EJ; Touw IP; FitzGerald DJ; Kreitman RJ; Hagenbeek A; Martens AC
Leukemia; 1998 May; 12(5):710-7. PubMed ID: 9593269
[TBL] [Abstract][Full Text] [Related]
11. Acute myeloid leukemia cells in G0 phase of the cell cycle that are unresponsive to conventional chemotherapy are sensitive to treatment with granulocyte-macrophage colony-stimulating factor/diphtheria toxin fusion proteins.
Jedema I; Barge RM; Frankel AE; Willemze R; Falkenburg JH
Exp Hematol; 2004 Feb; 32(2):188-94. PubMed ID: 15102480
[TBL] [Abstract][Full Text] [Related]
12. DT388-GM-CSF, a novel fusion toxin consisting of a truncated diphtheria toxin fused to human granulocyte-macrophage colony-stimulating factor, prolongs host survival in a SCID mouse model of acute myeloid leukemia.
Hall PD; Willingham MC; Kreitman RJ; Frankel AE
Leukemia; 1999 Apr; 13(4):629-33. PubMed ID: 10214872
[TBL] [Abstract][Full Text] [Related]
13. Antibody response to DT-GM, a novel fusion toxin consisting of a truncated diphtheria toxin (DT) linked to human granulocyte-macrophage colony stimulating factor (GM), during a phase I trial of patients with relapsed or refractory acute myeloid leukemia.
Hall PD; Virella G; Willoughby T; Atchley DH; Kreitman RJ; Frankel AE
Clin Immunol; 2001 Aug; 100(2):191-7. PubMed ID: 11465948
[TBL] [Abstract][Full Text] [Related]
14. Sensitivity of human acute myeloid leukaemia to diphtheria toxin-GM-CSF fusion protein.
Rozemuller H; Rombouts EJ; Touw IP; FitzGerald DJ; Kreitman RJ; Pastan I; Hagenbeek A; Martens AC
Br J Haematol; 1997 Sep; 98(4):952-9. PubMed ID: 9326195
[TBL] [Abstract][Full Text] [Related]
15. Comparison of in vivo and in vitro effects of granulocyte-macrophage colony-stimulating factor (GM-CSF) in patients with acute myeloid leukemia.
Estrov Z; Estey EH; Andreeff M; Talpaz M; Kurzrock R; Reading CL; Deisseroth AB; Gutterman JU
Exp Hematol; 1992 Jun; 20(5):558-64. PubMed ID: 1587302
[TBL] [Abstract][Full Text] [Related]
16. Modulation of the apoptotic response of human myeloid leukemia cells to a diphtheria toxin granulocyte-macrophage colony-stimulating factor fusion protein.
Frankel AE; Hall PD; Burbage C; Vesely J; Willingham M; Bhalla K; Kreitman RJ
Blood; 1997 Nov; 90(9):3654-61. PubMed ID: 9345050
[TBL] [Abstract][Full Text] [Related]
17. Enhanced ceramide generation and induction of apoptosis in human leukemia cells exposed to DT(388)-granulocyte-macrophage colony-stimulating factor (GM-CSF), a truncated diphtheria toxin fused to human GM-CSF.
Senchenkov A; Han TY; Wang H; Frankel AE; Kottke TJ; Kaufmann SH; Cabot MC
Blood; 2001 Sep; 98(6):1927-34. PubMed ID: 11535531
[TBL] [Abstract][Full Text] [Related]
18. Human recombinant interferon-inducible protein-10 inhibits the proliferation of normal and acute myelogenous leukemia progenitors.
Sarris AH; Talpaz M; Deisseroth AB; Estrov Z
Leukemia; 1996 May; 10(5):757-65. PubMed ID: 8656668
[TBL] [Abstract][Full Text] [Related]
19. Expression of interleukin-3 receptor subunits on defined subpopulations of acute myeloid leukemia blasts predicts the cytotoxicity of diphtheria toxin interleukin-3 fusion protein against malignant progenitors that engraft in immunodeficient mice.
Yalcintepe L; Frankel AE; Hogge DE
Blood; 2006 Nov; 108(10):3530-7. PubMed ID: 16882709
[TBL] [Abstract][Full Text] [Related]
20. Recombinant toxins containing human granulocyte-macrophage colony-stimulating factor and either pseudomonas exotoxin or diphtheria toxin kill gastrointestinal cancer and leukemia cells.
Kreitman RJ; Pastan I
Blood; 1997 Jul; 90(1):252-9. PubMed ID: 9207460
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]