169 related articles for article (PubMed ID: 9346340)
1. Novel persistent activation of muscarinic M1 receptors by xanomeline.
Christopoulos A; El-Fakahany EE
Eur J Pharmacol; 1997 Sep; 334(1):R3-4. PubMed ID: 9346340
[TBL] [Abstract][Full Text] [Related]
2. Pharmacological analysis of the novel mode of interaction between xanomeline and the M1 muscarinic acetylcholine receptor.
Christopoulos A; Parsons AM; El-Fakahany EE
J Pharmacol Exp Ther; 1999 Jun; 289(3):1220-8. PubMed ID: 10336509
[TBL] [Abstract][Full Text] [Related]
3. On the unique binding and activating properties of xanomeline at the M1 muscarinic acetylcholine receptor.
Christopoulos A; Pierce TL; Sorman JL; El-Fakahany EE
Mol Pharmacol; 1998 Jun; 53(6):1120-30. PubMed ID: 9614217
[TBL] [Abstract][Full Text] [Related]
4. Enhancement of maximal activation of neuronal nitric oxide synthase at muscarinic M1 receptors following prolonged agonist treatment.
Cuadra AE; El-Fakahany EE
Eur J Pharmacol; 1997 Sep; 334(1):107-10. PubMed ID: 9346336
[TBL] [Abstract][Full Text] [Related]
5. The muscarinic M1 agonist xanomeline increases soluble amyloid precursor protein release from Chinese hamster ovary-m1 cells.
Eckols K; Bymaster FP; Mitch CH; Shannon HE; Ward JS; DeLapp NW
Life Sci; 1995; 57(12):1183-90. PubMed ID: 7674807
[TBL] [Abstract][Full Text] [Related]
6. Differences in kinetics of xanomeline binding and selectivity of activation of G proteins at M(1) and M(2) muscarinic acetylcholine receptors.
Jakubík J; El-Fakahany EE; Dolezal V
Mol Pharmacol; 2006 Aug; 70(2):656-66. PubMed ID: 16675658
[TBL] [Abstract][Full Text] [Related]
7. Effects of the M1 agonist xanomeline on processing of human beta-amyloid precursor protein (FAD, Swedish mutant) transfected into Chinese hamster ovary-m1 cells.
DeLapp N; Wu S; Belagaje R; Johnstone E; Little S; Shannon H; Bymaster F; Calligaro D; Mitch C; Whitesitt C; Ward J; Sheardown M; Fink-Jensen A; Jeppesen L; Thomsen C; Sauerberg P
Biochem Biophys Res Commun; 1998 Mar; 244(1):156-60. PubMed ID: 9514902
[TBL] [Abstract][Full Text] [Related]
8. Long-term changes in the muscarinic M1 receptor induced by instantaneous formation of wash-resistant xanomeline-receptor complex.
De Lorme KC; Grant MK; Noetzel MJ; Polson SB; El-Fakahany EE
J Pharmacol Exp Ther; 2007 Dec; 323(3):868-76. PubMed ID: 17855477
[TBL] [Abstract][Full Text] [Related]
9. Persistent binding and functional antagonism by xanomeline at the muscarinic M5 receptor.
Grant MK; El-Fakahany EE
J Pharmacol Exp Ther; 2005 Oct; 315(1):313-9. PubMed ID: 16002459
[TBL] [Abstract][Full Text] [Related]
10. Long-term wash-resistant effects of brief interaction of xanomeline at the M1 muscarinic receptor.
De Lorme KC; Sikorski KL; Grant MK; El-Fakahany EE
Neurosci Lett; 2006 Dec; 410(1):11-4. PubMed ID: 17052840
[TBL] [Abstract][Full Text] [Related]
11. Low-affinity M(2) receptor binding state mediates mouse atrial bradycardia: comparative effects of carbamylcholine and the M(1) receptor agonists sabcomeline and xanomeline.
Stengel PW; Cohen ML
J Pharmacol Exp Ther; 2001 Mar; 296(3):818-24. PubMed ID: 11181912
[TBL] [Abstract][Full Text] [Related]
12. Allosteric modulation by persistent binding of xanomeline of the interaction of competitive ligands with the M1 muscarinic acetylcholine receptor.
Jakubík J; Tucek S; El-Fakahany EE
J Pharmacol Exp Ther; 2002 Jun; 301(3):1033-41. PubMed ID: 12023535
[TBL] [Abstract][Full Text] [Related]
13. Mechanisms of M3 muscarinic receptor regulation by wash-resistant xanomeline binding.
Noetzel MJ; Grant MK; El-Fakahany EE
Pharmacology; 2009; 83(5):301-17. PubMed ID: 19401618
[TBL] [Abstract][Full Text] [Related]
14. Xanomeline: a novel muscarinic receptor agonist with functional selectivity for M1 receptors.
Shannon HE; Bymaster FP; Calligaro DO; Greenwood B; Mitch CH; Sawyer BD; Ward JS; Wong DT; Olesen PH; Sheardown MJ; Swedberg MD; Suzdak PD; Sauerberg P
J Pharmacol Exp Ther; 1994 Apr; 269(1):271-81. PubMed ID: 7909557
[TBL] [Abstract][Full Text] [Related]
15. Role of receptor protein and membrane lipids in xanomeline wash-resistant binding to muscarinic M1 receptors.
Jakubík J; Tucek S; El-Fakahany EE
J Pharmacol Exp Ther; 2004 Jan; 308(1):105-10. PubMed ID: 14569060
[TBL] [Abstract][Full Text] [Related]
16. Identification of side chains on 1,2,5-thiadiazole-azacycles optimal for muscarinic m1 receptor activation.
Sauerberg P; Jeppesen L; Olesen PH; Sheardown MJ; Fink-Jensen A; Rasmussen T; Rimvall K; Shannon HE; Bymaster FP; DeLapp NW; Calligaro DO; Ward JS; Whitesitt CA; Thomsen C
Bioorg Med Chem Lett; 1998 Oct; 8(20):2897-902. PubMed ID: 9873644
[TBL] [Abstract][Full Text] [Related]
17. Classical and atypical agonists activate M1 muscarinic acetylcholine receptors through common mechanisms.
Randáková A; Dolejší E; Rudajev V; Zimčík P; Doležal V; El-Fakahany EE; Jakubík J
Pharmacol Res; 2015 Jul; 97():27-39. PubMed ID: 25882246
[TBL] [Abstract][Full Text] [Related]
18. Pharmacological evaluation of the long-term effects of xanomeline on the M(1) muscarinic acetylcholine receptor.
Grant MK; Noetzel MJ; De Lorme KC; Jakubík J; Doležal V; El-Fakahany EE
PLoS One; 2010 Dec; 5(12):e15722. PubMed ID: 21203415
[TBL] [Abstract][Full Text] [Related]
19. Up-regulation of the neuronal form of nitric oxide synthase in response to prolonged muscarinic M1 receptor stimulation.
Cuadra AE; El-Fakahany EE
J Neurochem; 1998 Aug; 71(2):571-9. PubMed ID: 9681447
[TBL] [Abstract][Full Text] [Related]
20. Differential coupling of m1, m3, and m5 muscarinic receptors to activation of neuronal nitric oxide synthase.
Wang SZ; Lee SY; Zhu SZ; el-Fakahany EE
Pharmacology; 1996 Nov; 53(5):271-80. PubMed ID: 8990485
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
