These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

144 related articles for article (PubMed ID: 9353194)

  • 1. Structural plasticity in a remodeled protein-protein interface.
    Atwell S; Ultsch M; De Vos AM; Wells JA
    Science; 1997 Nov; 278(5340):1125-8. PubMed ID: 9353194
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure of a phage display-derived variant of human growth hormone complexed to two copies of the extracellular domain of its receptor: evidence for strong structural coupling between receptor binding sites.
    Schiffer C; Ultsch M; Walsh S; Somers W; de Vos AM; Kossiakoff A
    J Mol Biol; 2002 Feb; 316(2):277-89. PubMed ID: 11851338
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The functional binding epitope of a high affinity variant of human growth hormone mapped by shotgun alanine-scanning mutagenesis: insights into the mechanisms responsible for improved affinity.
    Pal G; Kossiakoff AA; Sidhu SS
    J Mol Biol; 2003 Sep; 332(1):195-204. PubMed ID: 12946357
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Computational detection of the binding-site hot spot at the remodeled human growth hormone-receptor interface.
    Verkhivker GM; Bouzida D; Gehlhaar DK; Rejto PA; Freer ST; Rose PW
    Proteins; 2003 Nov; 53(2):201-19. PubMed ID: 14517972
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dissecting the binding energy epitope of a high-affinity variant of human growth hormone: cooperative and additive effects from combining mutations from independently selected phage display mutagenesis libraries.
    Bernat B; Sun M; Dwyer M; Feldkamp M; Kossiakoff AA
    Biochemistry; 2004 May; 43(20):6076-84. PubMed ID: 15147191
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Systematic profiling of clinical missence mutation effects on the intermolecular interaction between human growth hormone and its receptor in isolated growth hormone deficiency.
    Liu H; Xu L; Huang H; Zhao P; Yang R; Zhou Q; Liu G
    J Mol Graph Model; 2019 Nov; 92():1-7. PubMed ID: 31279174
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural and functional analysis of the 1:1 growth hormone:receptor complex reveals the molecular basis for receptor affinity.
    Clackson T; Ultsch MH; Wells JA; de Vos AM
    J Mol Biol; 1998 Apr; 277(5):1111-28. PubMed ID: 9571026
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Turning the growth hormone receptor on: evidence that hormone binding induces subunit rotation.
    Poger D; Mark AE
    Proteins; 2010 Apr; 78(5):1163-74. PubMed ID: 19927328
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Designing small-molecule switches for protein-protein interactions.
    Guo Z; Zhou D; Schultz PG
    Science; 2000 Jun; 288(5473):2042-5. PubMed ID: 10856217
    [TBL] [Abstract][Full Text] [Related]  

  • 10. High copy display of large proteins on phage for functional selections.
    Sidhu SS; Weiss GA; Wells JA
    J Mol Biol; 2000 Feb; 296(2):487-95. PubMed ID: 10669603
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Shotgun alanine scanning shows that growth hormone can bind productively to its receptor through a drastically minimized interface.
    Kouadio JL; Horn JR; Pal G; Kossiakoff AA
    J Biol Chem; 2005 Jul; 280(27):25524-32. PubMed ID: 15857837
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A hot spot of binding energy in a hormone-receptor interface.
    Clackson T; Wells JA
    Science; 1995 Jan; 267(5196):383-6. PubMed ID: 7529940
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The high- and low-affinity receptor binding sites of growth hormone are allosterically coupled.
    Walsh ST; Sylvester JE; Kossiakoff AA
    Proc Natl Acad Sci U S A; 2004 Dec; 101(49):17078-83. PubMed ID: 15563602
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Selecting high-affinity binding proteins by monovalent phage display.
    Lowman HB; Bass SH; Simpson N; Wells JA
    Biochemistry; 1991 Nov; 30(45):10832-8. PubMed ID: 1932005
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural basis of non-specific lipid binding in maize lipid-transfer protein complexes revealed by high-resolution X-ray crystallography.
    Han GW; Lee JY; Song HK; Chang C; Min K; Moon J; Shin DH; Kopka ML; Sawaya MR; Yuan HS; Kim TD; Choe J; Lim D; Moon HJ; Suh SW
    J Mol Biol; 2001 Apr; 308(2):263-78. PubMed ID: 11327766
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Alternative views of functional protein binding epitopes obtained by combinatorial shotgun scanning mutagenesis.
    Pál G; Fong SY; Kossiakoff AA; Sidhu SS
    Protein Sci; 2005 Sep; 14(9):2405-13. PubMed ID: 16131663
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Affinity maturation of human growth hormone by monovalent phage display.
    Lowman HB; Wells JA
    J Mol Biol; 1993 Dec; 234(3):564-78. PubMed ID: 8254660
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of residues outside the two binding sites that are critical for activation of the lactogenic activity of human growth hormone.
    Duda KM; Brooks CL
    J Biol Chem; 2003 Jun; 278(25):22734-9. PubMed ID: 12682073
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ternary complex between placental lactogen and the extracellular domain of the prolactin receptor.
    Elkins PA; Christinger HW; Sandowski Y; Sakal E; Gertler A; de Vos AM; Kossiakoff AA
    Nat Struct Biol; 2000 Sep; 7(9):808-15. PubMed ID: 10966654
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The role of protein dynamics in increasing binding affinity for an engineered protein-protein interaction established by H/D exchange mass spectrometry.
    Horn JR; Kraybill B; Petro EJ; Coales SJ; Morrow JA; Hamuro Y; Kossiakoff AA
    Biochemistry; 2006 Jul; 45(28):8488-98. PubMed ID: 16834322
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.