These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

171 related articles for article (PubMed ID: 9353358)

  • 1. Prediction of species differences (rats, dogs, humans) in the in vivo metabolic clearance of YM796 by the liver from in vitro data.
    Iwatsubo T; Suzuki H; Sugiyama Y
    J Pharmacol Exp Ther; 1997 Nov; 283(2):462-9. PubMed ID: 9353358
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Prediction of in vivo hepatic metabolic clearance of YM796 from in vitro data by use of human liver microsomes and recombinant P-450 isozymes.
    Iwatsubo T; Suzuki H; Shimada N; Chiba K; Ishizaki T; Green CE; Tyson CA; Yokoi T; Kamataki T; Sugiyama Y
    J Pharmacol Exp Ther; 1997 Aug; 282(2):909-19. PubMed ID: 9262358
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Prediction of in vivo nonlinear first-pass hepatic metabolism of YM796 from in vitro metabolic data.
    Iwatsubo T; Hisaka A; Suzuki H; Sugiyama Y
    J Pharmacol Exp Ther; 1998 Jul; 286(1):122-7. PubMed ID: 9655850
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Species differences in the pharmacokinetics and metabolism of indinavir, a potent human immunodeficiency virus protease inhibitor.
    Lin JH; Chiba M; Balani SK; Chen IW; Kwei GY; Vastag KJ; Nishime JA
    Drug Metab Dispos; 1996 Oct; 24(10):1111-20. PubMed ID: 8894513
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Species differences in the metabolism of a potent HIV-1 reverse transcriptase inhibitor L-738,372. In vivo and in vitro studies in rats, dogs, monkeys, and human.
    Prueksaritanont T; Balani SK; Dwyer LM; Ellis JD; Kauffman LR; Varga SL; Pitzenberger SM; Theoharides AD
    Drug Metab Dispos; 1995 Jul; 23(7):688-95. PubMed ID: 7587955
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Determination of the rate-limiting step in the hepatic elimination of YM796 by isolated rat hepatocytes.
    Iwatsubo T; Suzuki H; Sugiyama Y
    Pharm Res; 1999 Jan; 16(1):110-6. PubMed ID: 9950288
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Prediction of human hepatic clearance from in vivo animal experiments and in vitro metabolic studies with liver microsomes from animals and humans.
    Naritomi Y; Terashita S; Kimura S; Suzuki A; Kagayama A; Sugiyama Y
    Drug Metab Dispos; 2001 Oct; 29(10):1316-24. PubMed ID: 11560875
    [TBL] [Abstract][Full Text] [Related]  

  • 8. In vivo disposition of caffeine predicted from hepatic microsomal and hepatocyte data.
    Hayes KA; Brennan B; Chenery R; Houston JB
    Drug Metab Dispos; 1995 Mar; 23(3):349-53. PubMed ID: 7628300
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pharmacokinetics of troglitazone, an antidiabetic agent: prediction of in vivo stereoselective sulfation and glucuronidation from in vitro data.
    Izumi T; Hosiyama K; Enomoto S; Sasahara K; Sugiyama Y
    J Pharmacol Exp Ther; 1997 Mar; 280(3):1392-400. PubMed ID: 9067328
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Prediction of in vivo disposition from in vitro systems: clearance of phenytoin and tolbutamide using rat hepatic microsomal and hepatocyte data.
    Ashforth EI; Carlile DJ; Chenery R; Houston JB
    J Pharmacol Exp Ther; 1995 Aug; 274(2):761-6. PubMed ID: 7636740
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Gender differences in the metabolism and pharmacokinetics of the experimental anticancer agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA).
    Zhou S; Kestell P; Tingle MD; Paxton JW
    Cancer Chemother Pharmacol; 2002 Feb; 49(2):126-32. PubMed ID: 11862426
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Species and organ differences in first-pass metabolism of the ester prodrug L-751,164 in dogs and monkeys. In vivo and in vitro studies.
    Prueksaritanont T; Gorham LM; Ellis JD; Fernandez-Metzler C; Deluna P; Gehret JR; Strong KL; Hochman JH; Askew BC; Duggan ME; Gilbert JD; Lin JH; Vyas KP
    Drug Metab Dispos; 1996 Nov; 24(11):1263-71. PubMed ID: 8937862
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Metabolic disposition of tacrine in primary suspensions of rat hepatocyte and in single-pass perfused liver: in vitro/in vivo comparisons.
    Kukan M; Bezek S; Pool WF; Woolf TF
    Xenobiotica; 1994 Nov; 24(11):1107-17. PubMed ID: 7701852
    [TBL] [Abstract][Full Text] [Related]  

  • 14. NTP technical report on the toxicity and metabolism studies of chloral hydrate (CAS No. 302-17-0). Administered by gavage to F344/N rats and B6C3F1 mice.
    Beland FA
    Toxic Rep Ser; 1999 Aug; (59):1-66, A1-E7. PubMed ID: 11803702
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In vivo clearance of ethoxycoumarin and its prediction from In vitro systems. Use Of drug depletion and metabolite formation methods in hepatic microsomes and isolated hepatocytes.
    Carlile DJ; Stevens AJ; Ashforth EI; Waghela D; Houston JB
    Drug Metab Dispos; 1998 Mar; 26(3):216-21. PubMed ID: 9492383
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Stereoselective metabolism of tazofelone, an anti-inflammatory bowel disease agent, in rats and dogs and in human liver microsomes.
    Clay MP; Hanssen BR; Surapaneni SS; Lindstrom TD
    Chirality; 1999; 11(3):233-40. PubMed ID: 10079502
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Preclinical pharmacokinetics and metabolism of 6-(4-(2,5-difluorophenyl)oxazol-5-yl)-3-isopropyl-[1,2,4]-triazolo[4,3-a]pyridine, a novel and selective p38alpha inhibitor: identification of an active metabolite in preclinical species and human liver microsomes.
    Kalgutkar AS; Hatch HL; Kosea F; Nguyen HT; Choo EF; McClure KF; Taylor TJ; Henne KR; Kuperman AV; Dombroski MA; Letavic MA
    Biopharm Drug Dispos; 2006 Nov; 27(8):371-86. PubMed ID: 16944451
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Stereoselective metabolism of felodipine in liver microsomes from rat, dog, and human.
    Eriksson UG; Lundahl J; Bäärnhielm C; Regårdh CG
    Drug Metab Dispos; 1991; 19(5):889-94. PubMed ID: 1686232
    [TBL] [Abstract][Full Text] [Related]  

  • 19. 7-Ethoxycoumarin O-deethylase kinetics in isolated rat, dog and human hepatocyte suspensions.
    Bayliss MK; Bell JA; Wilson K; Park GR
    Xenobiotica; 1994 Mar; 24(3):231-41. PubMed ID: 8009886
    [TBL] [Abstract][Full Text] [Related]  

  • 20. In vitro-in vivo correlation of the pharmacokinetics of vinpocetine.
    Szakács T; Veres Z; Vereczkey L
    Pol J Pharmacol; 2001; 53(6):623-8. PubMed ID: 11985336
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.