BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

257 related articles for article (PubMed ID: 9381732)

  • 1. Identification of human cytochrome P450 isoforms involved in the metabolism of brotizolam.
    Senda C; Kishimoto W; Sakai K; Nagakura A; Igarashi T
    Xenobiotica; 1997 Sep; 27(9):913-22. PubMed ID: 9381732
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of human cytochrome P450 isoforms involved in the 3-hydroxylation of quinine by human live microsomes and nine recombinant human cytochromes P450.
    Zhao XJ; Yokoyama H; Chiba K; Wanwimolruk S; Ishizaki T
    J Pharmacol Exp Ther; 1996 Dec; 279(3):1327-34. PubMed ID: 8968357
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of human cytochrome P450 isoforms involved in the metabolism of S-2-[4-(3-methyl-2-thienyl)phenyl]propionic acid.
    Taguchi K; Konishi T; Nishikawa H; Kitamura S
    Xenobiotica; 1999 Sep; 29(9):899-907. PubMed ID: 10548450
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of CYP3A4 as the predominant isoform responsible for the metabolism of ambroxol in human liver microsomes.
    Ishiguro N; Senda C; Kishimoto W; Sakai K; Funae Y; Igarashi T
    Xenobiotica; 2000 Jan; 30(1):71-80. PubMed ID: 10659952
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Contribution of human cytochrome p-450 isoforms to the metabolism of the simplest phenothiazine neuroleptic promazine.
    Wójcikowski J; Pichard-Garcia L; Maurel P; Daniel WA
    Br J Pharmacol; 2003 Apr; 138(8):1465-74. PubMed ID: 12721102
    [TBL] [Abstract][Full Text] [Related]  

  • 6. In vitro metabolism of quinidine: the (3S)-3-hydroxylation of quinidine is a specific marker reaction for cytochrome P-4503A4 activity in human liver microsomes.
    Nielsen TL; Rasmussen BB; Flinois JP; Beaune P; Brosen K
    J Pharmacol Exp Ther; 1999 Apr; 289(1):31-7. PubMed ID: 10086984
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of cytochrome P450 forms involved in the 4-hydroxylation of valsartan, a potent and specific angiotensin II receptor antagonist, in human liver microsomes.
    Nakashima A; Kawashita H; Masuda N; Saxer C; Niina M; Nagae Y; Iwasaki K
    Xenobiotica; 2005 Jun; 35(6):589-602. PubMed ID: 16192110
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Nortriptyline E-10-hydroxylation in vitro is mediated by human CYP2D6 (high affinity) and CYP3A4 (low affinity): implications for interactions with enzyme-inducing drugs.
    Venkatakrishnan K; von Moltke LL; Greenblatt DJ
    J Clin Pharmacol; 1999 Jun; 39(6):567-77. PubMed ID: 10354960
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Kinetic analysis of the activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by heterologously expressed human P450 enzymes and the effect of P450-specific chemical inhibitors on this activation in human liver microsomes.
    Patten CJ; Smith TJ; Murphy SE; Wang MH; Lee J; Tynes RE; Koch P; Yang CS
    Arch Biochem Biophys; 1996 Sep; 333(1):127-38. PubMed ID: 8806763
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of cytochrome P450 enzymes involved in the metabolism of zotepine, an antipsychotic drug, in human liver microsomes.
    Shiraga T; Kaneko H; Iwasaki K; Tozuka Z; Suzuki A; Hata T
    Xenobiotica; 1999 Mar; 29(3):217-29. PubMed ID: 10219963
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Kinetic characterization and identification of the enzymes responsible for the hepatic biotransformation of adinazolam and N-desmethyladinazolam in man.
    Venkatakrishnan K; von Moltke LL; Duan SX; Fleishaker JC; Shader RI; Greenblatt DJ
    J Pharm Pharmacol; 1998 Mar; 50(3):265-74. PubMed ID: 9600717
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cytochrome P4502B6 and 2C9 do not metabolize midazolam: kinetic analysis and inhibition study with monoclonal antibodies.
    Hamaoka N; Oda Y; Hase I; Asada A
    Br J Anaesth; 2001 Apr; 86(4):540-4. PubMed ID: 11573629
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of human CYP isoforms involved in the metabolism of propranolol enantiomers--N-desisopropylation is mediated mainly by CYP1A2.
    Yoshimoto K; Echizen H; Chiba K; Tani M; Ishizaki T
    Br J Clin Pharmacol; 1995 Apr; 39(4):421-31. PubMed ID: 7640150
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Variable contribution of cytochromes P450 2D6, 2C9 and 3A4 to the 4-hydroxylation of tamoxifen by human liver microsomes.
    Crewe HK; Ellis SW; Lennard MS; Tucker GT
    Biochem Pharmacol; 1997 Jan; 53(2):171-8. PubMed ID: 9037249
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Human reductive halothane metabolism in vitro is catalyzed by cytochrome P450 2A6 and 3A4.
    Spracklin DK; Thummel KE; Kharasch ED
    Drug Metab Dispos; 1996 Sep; 24(9):976-83. PubMed ID: 8886607
    [TBL] [Abstract][Full Text] [Related]  

  • 16. In vitro metabolism and drug interaction potential of a new highly potent anti-cytomegalovirus molecule, CMV423 (2-chloro 3-pyridine 3-yl 5,6,7,8-tetrahydroindolizine I-carboxamide).
    Bournique B; Lambert N; Boukaiba R; Martinet M
    Br J Clin Pharmacol; 2001 Jul; 52(1):53-63. PubMed ID: 11453890
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of the human cytochrome P450 isoforms mediating in vitro N-dealkylation of perphenazine.
    Olesen OV; Linnet K
    Br J Clin Pharmacol; 2000 Dec; 50(6):563-71. PubMed ID: 11136295
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Biotransformation of parathion in human liver: participation of CYP3A4 and its inactivation during microsomal parathion oxidation.
    Butler AM; Murray M
    J Pharmacol Exp Ther; 1997 Feb; 280(2):966-73. PubMed ID: 9023313
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of human cytochrome P450 isoforms involved in the stereoselective metabolism of mianserin enantiomers.
    Koyama E; Chiba K; Tani M; Ishizaki T
    J Pharmacol Exp Ther; 1996 Jul; 278(1):21-30. PubMed ID: 8764331
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Involvement of human cytochrome P450 3A4 in reduced haloperidol oxidation.
    Kudo S; Odomi M
    Eur J Clin Pharmacol; 1998 May; 54(3):253-9. PubMed ID: 9681669
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.