These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. PACE4 expression in mouse basal keratinocytes results in basement membrane disruption and acceleration of tumor progression. Bassi DE; Lopez De Cicco R; Cenna J; Litwin S; Cukierman E; Klein-Szanto AJ Cancer Res; 2005 Aug; 65(16):7310-9. PubMed ID: 16103082 [TBL] [Abstract][Full Text] [Related]
4. Enhanced aggressiveness of benzopyrene-induced squamous carcinomas in transgenic mice overexpressing the proprotein convertase PACE4 (PCSK6). Bassi DE; Cenna J; Zhang J; Cukierman E; Klein-Szanto AJ Mol Carcinog; 2015 Oct; 54(10):1122-31. PubMed ID: 24845697 [TBL] [Abstract][Full Text] [Related]
5. Transcriptional regulation of subtilisin-like proprotein convertase PACE4 by E2F: possible role of E2F-mediated upregulation of PACE4 in tumor progression. Yuasa K; Suzue K; Nagahama M; Matsuda Y; Tsuji A Gene; 2007 Nov; 402(1-2):103-10. PubMed ID: 17825503 [TBL] [Abstract][Full Text] [Related]
6. Correlation of proteolytic cleavage of F protein precursors in paramyxoviruses with expression of the fur, PACE4 and PC6 genes in mammalian cells. Sakaguchi T; Fujii Y; Kiyotani K; Yoshida T J Gen Virol; 1994 Oct; 75 ( Pt 10)():2821-7. PubMed ID: 7931173 [TBL] [Abstract][Full Text] [Related]
7. Subtilisin-like proprotein convertase PACE4 (SPC4) is a candidate processing enzyme of bone morphogenetic proteins during tooth formation. Akamatsu T; Matsuda Y; Tsumura K; Tada J; Parvin MN; Kanamori N; Hosoi K Dev Dyn; 1999 Dec; 216(4-5):481-8. PubMed ID: 10633867 [TBL] [Abstract][Full Text] [Related]
9. The developmental expression in the rat CNS and peripheral tissues of proteases PC5 and PACE4 mRNAs: comparison with other proprotein processing enzymes. Zheng M; Seidah NG; Pintar JE Dev Biol; 1997 Jan; 181(2):268-83. PubMed ID: 9013936 [TBL] [Abstract][Full Text] [Related]
10. A switch from stromal to tumor cell expression of stromelysin-1 mRNA associated with the conversion of squamous to spindle carcinomas during mouse skin tumor progression. Wright JH; McDonnell S; Portella G; Bowden GT; Balmain A; Matrisian LM Mol Carcinog; 1994 Aug; 10(4):207-15. PubMed ID: 8068181 [TBL] [Abstract][Full Text] [Related]
11. Multi-Leu PACE4 Inhibitor Retention within Cells Is PACE4 Dependent and a Prerequisite for Antiproliferative Activity. Couture F; Ly K; Levesque C; Kwiatkowska A; Ait-Mohand S; Desjardins R; Guérin B; Day R Biomed Res Int; 2015; 2015():824014. PubMed ID: 26114115 [TBL] [Abstract][Full Text] [Related]
12. Role of prohormone convertases in pro-neuropeptide Y processing: coexpression and in vitro kinetic investigations. Brakch N; Rist B; Beck-Sickinger AG; Goenaga J; Wittek R; Bürger E; Brunner HR; Grouzmann E Biochemistry; 1997 Dec; 36(51):16309-20. PubMed ID: 9405066 [TBL] [Abstract][Full Text] [Related]
13. Furin inhibition results in absent or decreased invasiveness and tumorigenicity of human cancer cells. Bassi DE; Lopez De Cicco R; Mahloogi H; Zucker S; Thomas G; Klein-Szanto AJ Proc Natl Acad Sci U S A; 2001 Aug; 98(18):10326-31. PubMed ID: 11517338 [TBL] [Abstract][Full Text] [Related]
14. Collagenase-3 (MMP-13) is expressed by tumor cells in invasive vulvar squamous cell carcinomas. Johansson N; Vaalamo M; Grénman S; Hietanen S; Klemi P; Saarialho-Kere U; Kähäri VM Am J Pathol; 1999 Feb; 154(2):469-80. PubMed ID: 10027405 [TBL] [Abstract][Full Text] [Related]
15. Biosynthetic processing and quaternary interactions of proprotein convertase SPC4 (PACE4). Nagahama M; Taniguchi T; Hashimoto E; Imamaki A; Mori K; Tsuji A; Matsuda Y FEBS Lett; 1998 Aug; 434(1-2):155-9. PubMed ID: 9738469 [TBL] [Abstract][Full Text] [Related]
16. Low-dose retinoic acid enhances in vitro invasiveness of human oral squamous-cell-carcinoma cell lines. Uchida D; Kawamata H; Nakashiro K; Omotehara F; Hino S; Hoque MO; Begum NM; Yoshida H; Sato M; Fujimori T Br J Cancer; 2001 Jul; 85(1):122-8. PubMed ID: 11437413 [TBL] [Abstract][Full Text] [Related]
17. PACE4 is an important driver of ZR-75-1 estrogen receptor-positive breast cancer proliferation and tumor progression. Panet F; Couture F; Kwiatkowska A; Desjardins R; Guérin B; Day R Eur J Cell Biol; 2017 Aug; 96(5):469-475. PubMed ID: 28347547 [TBL] [Abstract][Full Text] [Related]
18. Furin-dependent intracellular activation of the human stromelysin-3 zymogen. Pei D; Weiss SJ Nature; 1995 May; 375(6528):244-7. PubMed ID: 7746327 [TBL] [Abstract][Full Text] [Related]
19. The cysteine-rich domain of the secreted proprotein convertases PC5A and PACE4 functions as a cell surface anchor and interacts with tissue inhibitors of metalloproteinases. Nour N; Mayer G; Mort JS; Salvas A; Mbikay M; Morrison CJ; Overall CM; Seidah NG Mol Biol Cell; 2005 Nov; 16(11):5215-26. PubMed ID: 16135528 [TBL] [Abstract][Full Text] [Related]