BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

960 related articles for article (PubMed ID: 9398321)

  • 1. Covalent attachment of ethidium to DNA results in enhanced topoisomerase II-mediated DNA cleavage.
    Marx G; Zhou H; Graves DE; Osheroff N
    Biochemistry; 1997 Dec; 36(50):15884-91. PubMed ID: 9398321
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Induction of topoisomerase II-mediated DNA cleavage by a protoberberine alkaloid, berberrubine.
    Kim SA; Kwon Y; Kim JH; Muller MT; Chung IK
    Biochemistry; 1998 Nov; 37(46):16316-24. PubMed ID: 9819224
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Quinolones share a common interaction domain on topoisomerase II with other DNA cleavage-enhancing antineoplastic drugs.
    Elsea SH; Westergaard M; Burden DA; Lomenick JP; Osheroff N
    Biochemistry; 1997 Mar; 36(10):2919-24. PubMed ID: 9062121
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Fluorometric assays for DNA topoisomerases and topoisomerase-targeted drugs: quantitation of catalytic activity and DNA cleavage.
    Andrea JE; Adachi K; Morgan AR
    Mol Pharmacol; 1991 Oct; 40(4):495-501. PubMed ID: 1656189
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Quinolone action against human topoisomerase IIalpha: stimulation of enzyme-mediated double-stranded DNA cleavage.
    Bromberg KD; Burgin AB; Osheroff N
    Biochemistry; 2003 Apr; 42(12):3393-8. PubMed ID: 12653542
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Anthocyanidins modulate the activity of human DNA topoisomerases I and II and affect cellular DNA integrity.
    Habermeyer M; Fritz J; Barthelmes HU; Christensen MO; Larsen MK; Boege F; Marko D
    Chem Res Toxicol; 2005 Sep; 18(9):1395-404. PubMed ID: 16167831
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sequence selectivity of topoisomerase II DNA cleavage stimulated by mitoxantrone derivatives: relationships to drug DNA binding and cellular effects.
    De Isabella P; Capranico G; Palumbo M; Sissi C; Krapcho AP; Zunino F
    Mol Pharmacol; 1993 May; 43(5):715-21. PubMed ID: 8388987
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Topoisomerase II mediated DNA lesions induced by acridine-4-carboxamide and 2-(4-pyridyl)quinoline-8-carboxamide.
    Woynarowski JM; McCarthy K; Reynolds B; Beerman TA; Denny WA
    Anticancer Drug Des; 1994 Feb; 9(1):9-24. PubMed ID: 8141968
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Chinese hamster ovary cells resistant to the topoisomerase II catalytic inhibitor ICRF-159: a Tyr49Phe mutation confers high-level resistance to bisdioxopiperazines.
    Sehested M; Wessel I; Jensen LH; Holm B; Oliveri RS; Kenwrick S; Creighton AM; Nitiss JL; Jensen PB
    Cancer Res; 1998 Apr; 58(7):1460-8. PubMed ID: 9537249
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Topoisomerase II-mediated DNA cleavage by amonafide and its structural analogs.
    Hsiang YH; Jiang JB; Liu LF
    Mol Pharmacol; 1989 Sep; 36(3):371-6. PubMed ID: 2550774
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Differential cytotoxic pathways of topoisomerase I and II anticancer agents after overexpression of the E2F-1/DP-1 transcription factor complex.
    Hofland K; Petersen BO; Falck J; Helin K; Jensen PB; Sehested M
    Clin Cancer Res; 2000 Apr; 6(4):1488-97. PubMed ID: 10778981
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Azatoxin is a mechanistic hybrid of the topoisomerase II-targeted anticancer drugs etoposide and ellipticine.
    Cline SD; Macdonald TL; Osheroff N
    Biochemistry; 1997 Oct; 36(42):13095-101. PubMed ID: 9335572
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Increased sensitivity to quinolone antibacterials can be engineered in human topoisomerase IIalpha by selective mutagenesis.
    Hammonds TR; Foster SR; Maxwell A
    J Mol Biol; 2000 Jul; 300(3):481-91. PubMed ID: 10884345
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Spontaneous DNA lesions poison human topoisomerase IIalpha and stimulate cleavage proximal to leukemic 11q23 chromosomal breakpoints.
    Kingma PS; Greider CA; Osheroff N
    Biochemistry; 1997 May; 36(20):5934-9. PubMed ID: 9166762
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The 9-position in berberine analogs is an important determinant of DNA topoisomerase II inhibition.
    Krishnan P; Bastow KF
    Anticancer Drug Des; 2000 Aug; 15(4):255-64. PubMed ID: 11200501
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Topoisomerase I-mediated DNA relaxation as a tool to study intercalation of small molecules into supercoiled DNA.
    Peixoto P; Bailly C; David-Cordonnier MH
    Methods Mol Biol; 2010; 613():235-56. PubMed ID: 19997888
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Phosphorylation of topoisomerase II by casein kinase II and protein kinase C: effects on enzyme-mediated DNA cleavage/religation and sensitivity to the antineoplastic drugs etoposide and 4'-(9-acridinylamino)methane-sulfon-m-anisidide.
    DeVore RF; Corbett AH; Osheroff N
    Cancer Res; 1992 Apr; 52(8):2156-61. PubMed ID: 1313738
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Changing a leucine to a lysine residue makes NaeI endonuclease hypersensitive to DNA intercalative drugs.
    Jo K; Topal MD
    Biochemistry; 1996 Aug; 35(31):10014-8. PubMed ID: 8756463
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Distinct patterns of cell cycle disturbance elicited by compounds interfering with DNA topoisomerase I and II activity.
    Poot M; Hiller KH; Heimpel S; Hoehn H
    Exp Cell Res; 1995 May; 218(1):326-30. PubMed ID: 7537696
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Evaluation of the clastogenic, DNA intercalative, and topoisomerase II-interactive properties of bioflavonoids in Chinese hamster V79 cells.
    Snyder RD; Gillies PJ
    Environ Mol Mutagen; 2002; 40(4):266-76. PubMed ID: 12489117
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 48.