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6. A requirement for Syk in the activation of the microtubule-associated protein kinase/phospholipase A2 pathway by Fc epsilon R1 is not shared by a G protein-coupled receptor. Hirasawa N; Scharenberg A; Yamamura H; Beaven MA; Kinet JP J Biol Chem; 1995 May; 270(18):10960-7. PubMed ID: 7537741 [TBL] [Abstract][Full Text] [Related]
7. Exposure of RBL-2H3 mast cells to Ag(+) induces cell degranulation and mediator release. Suzuki Y; Yoshimaru T; Yamashita K; Matsui T; Yamaki M; Shimizu K Biochem Biophys Res Commun; 2001 May; 283(3):707-14. PubMed ID: 11341783 [TBL] [Abstract][Full Text] [Related]
8. SH2 domain-mediated targeting, but not localization, of Syk in the plasma membrane is critical for FcepsilonRI signaling. Sada K; Zhang J; Siraganian RP Blood; 2001 Mar; 97(5):1352-9. PubMed ID: 11222380 [TBL] [Abstract][Full Text] [Related]
9. Phosphorylation of Syk activation loop tyrosines is essential for Syk function. An in vivo study using a specific anti-Syk activation loop phosphotyrosine antibody. Zhang J; Billingsley ML; Kincaid RL; Siraganian RP J Biol Chem; 2000 Nov; 275(45):35442-7. PubMed ID: 10931839 [TBL] [Abstract][Full Text] [Related]
10. Beta2 integrin-dependent phosphorylation of protein-tyrosine kinase Pyk2 stimulated by tumor necrosis factor alpha and fMLP in human neutrophils adherent to fibrinogen. Yan SR; Novak MJ FEBS Lett; 1999 May; 451(1):33-8. PubMed ID: 10356979 [TBL] [Abstract][Full Text] [Related]
11. Negative regulation of FcepsilonRI-mediated mast cell activation by a ubiquitin-protein ligase Cbl-b. Qu X; Sada K; Kyo S; Maeno K; Miah SM; Yamamura H Blood; 2004 Mar; 103(5):1779-86. PubMed ID: 14604964 [TBL] [Abstract][Full Text] [Related]
12. Syk is activated by phosphotyrosine-containing peptides representing the tyrosine-based activation motifs of the high affinity receptor for IgE. Shiue L; Zoller MJ; Brugge JS J Biol Chem; 1995 May; 270(18):10498-502. PubMed ID: 7537732 [TBL] [Abstract][Full Text] [Related]
13. Related adhesion focal tyrosine kinase and the epidermal growth factor receptor mediate the stimulation of mitogen-activated protein kinase by the G-protein-coupled P2Y2 receptor. Phorbol ester or [Ca2+]i elevation can substitute for receptor activation. Soltoff SP J Biol Chem; 1998 Sep; 273(36):23110-7. PubMed ID: 9722539 [TBL] [Abstract][Full Text] [Related]
14. Altered patterns of tyrosine phosphorylation and Syk activation for sterically restricted cyclic dimers of IgE-Fc epsilonRI. Harris NT; Goldstein B; Holowka D; Baird B Biochemistry; 1997 Feb; 36(8):2237-42. PubMed ID: 9047325 [TBL] [Abstract][Full Text] [Related]
15. Activation of Syk tyrosine kinase is required for c-Cbl-mediated ubiquitination of Fcepsilon RI and Syk in RBL cells. Paolini R; Molfetta R; Beitz LO; Zhang J; Scharenberg AM; Piccoli M; Frati L; Siraganian R; Santoni A J Biol Chem; 2002 Oct; 277(40):36940-7. PubMed ID: 12145291 [TBL] [Abstract][Full Text] [Related]
16. Overcoming the signaling defect of Lyn-sequestering, signal-curtailing FcepsilonRI dimers: aggregated dimers can dissociate from Lyn and form signaling complexes with Syk. Lara M; Ortega E; Pecht I; Pfeiffer JR; Martinez AM; Lee RJ; Surviladze Z; Wilson BS; Oliver JM J Immunol; 2001 Oct; 167(8):4329-37. PubMed ID: 11591756 [TBL] [Abstract][Full Text] [Related]
17. ER-27319, an acridone-related compound, inhibits release of antigen-induced allergic mediators from mast cells by selective inhibition of fcepsilon receptor I-mediated activation of Syk. Moriya K; Rivera J; Odom S; Sakuma Y; Muramato K; Yoshiuchi T; Miyamoto M; Yamada K Proc Natl Acad Sci U S A; 1997 Nov; 94(23):12539-44. PubMed ID: 9356485 [TBL] [Abstract][Full Text] [Related]
18. Fc epsilon RI aggregation induces tyrosine phosphorylation of a novel 72 kDa protein downstream of Syk. Hamawy MM; Fischler C; Zhang J; Siraganian RP Biochem Biophys Res Commun; 1997 Oct; 239(3):670-5. PubMed ID: 9367826 [TBL] [Abstract][Full Text] [Related]