BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

113 related articles for article (PubMed ID: 9416427)

  • 1. Inhibition of papain with 2-benzyl-3,4-epoxybutanoic acid esters. Mechanistic and stereochemical probe for cysteine protease catalysis.
    Kim DH; Jin Y; Ryu CH
    Bioorg Med Chem; 1997 Nov; 5(11):2103-8. PubMed ID: 9416427
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design of protease inhibitors on the basis of substrate stereospecificity.
    Kim DH
    Biopolymers; 1999; 51(1):3-8. PubMed ID: 10380348
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Azapeptides as inhibitors and active site titrants for cysteine proteinases.
    Xing R; Hanzlik RP
    J Med Chem; 1998 Apr; 41(8):1344-51. PubMed ID: 9548822
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Syntheses and kinetic evaluation of racemic and optically active 2-benzyl-2-methyl-3,4-epoxybutanoic acids as irreversible inactivators for carboxypeptidase A.
    Lee M; Kim DH
    Bioorg Med Chem; 2002 Apr; 10(4):913-22. PubMed ID: 11836098
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inactivation of cysteine proteases.
    Govardhan CP; Abeles RH
    Arch Biochem Biophys; 1996 Jun; 330(1):110-4. PubMed ID: 8651683
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mechanistic studies on the inactivation of papain by epoxysuccinyl inhibitors.
    Meara JP; Rich DH
    J Med Chem; 1996 Aug; 39(17):3357-66. PubMed ID: 8765519
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and evaluation of chloromethyl sulfoxides as a new class of selective irreversible cysteine protease inhibitors.
    Brouwer AJ; Bunschoten A; Liskamp RM
    Bioorg Med Chem; 2007 Nov; 15(22):6985-93. PubMed ID: 17869119
    [TBL] [Abstract][Full Text] [Related]  

  • 8. New peptidic cysteine protease inhibitors derived from the electrophilic alpha-amino acid aziridine-2,3-dicarboxylic acid.
    Schirmeister T
    J Med Chem; 1999 Feb; 42(4):560-72. PubMed ID: 10052963
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cysteine protease inhibition by azapeptide esters.
    Magrath J; Abeles RH
    J Med Chem; 1992 Nov; 35(23):4279-83. PubMed ID: 1447732
    [TBL] [Abstract][Full Text] [Related]  

  • 10. E64 [trans-epoxysuccinyl-L-leucylamido-(4-guanidino)butane] analogues as inhibitors of cysteine proteinases: investigation of S2 subsite interactions.
    Gour-Salin BJ; Lachance P; Magny MC; Plouffe C; Ménard R; Storer AC
    Biochem J; 1994 Apr; 299 ( Pt 2)(Pt 2):389-92. PubMed ID: 8172599
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Peptidyl beta-homo-aspartals (3-amino-4-carboxybutyraldehydes): new specific inhibitors of caspases.
    Bajusz S; Fauszt I; Németh K; Barabás E; Juhász A; Patthy M; Bauer PI
    Biopolymers; 1999; 51(1):109-18. PubMed ID: 10380358
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel aza peptide inhibitors and active-site probes of papain-family cysteine proteases.
    Verhelst SH; Witte MD; Arastu-Kapur S; Fonovic M; Bogyo M
    Chembiochem; 2006 Jun; 7(6):943-50. PubMed ID: 16607671
    [TBL] [Abstract][Full Text] [Related]  

  • 13. beta-Lactam derivatives as enzyme inhibitors: 1-peptidyl derivatives of 4-phenylazetidin-2-one as inhibitors of elastase and papain.
    Achilles K; Schirmeister T; Otto HH
    Arch Pharm (Weinheim); 2000 Aug; 333(8):243-53. PubMed ID: 11008374
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Peptide alpha-keto ester, alpha-keto amide, and alpha-keto acid inhibitors of calpains and other cysteine proteases.
    Li Z; Patil GS; Golubski ZE; Hori H; Tehrani K; Foreman JE; Eveleth DD; Bartus RT; Powers JC
    J Med Chem; 1993 Oct; 36(22):3472-80. PubMed ID: 8230139
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The mechanism of papain inhibition by peptidyl aldehydes.
    Shokhen M; Khazanov N; Albeck A
    Proteins; 2011 Mar; 79(3):975-85. PubMed ID: 21181719
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interactions of papaya proteinase IV with inhibitors.
    Buttle DJ; Ritonja A; Dando PM; Abrahamson M; Shaw EN; Wikstrom P; Turk V; Barrett AJ
    FEBS Lett; 1990 Mar; 262(1):58-60. PubMed ID: 1690669
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure-activity relationships for inhibition of papain by peptide Michael acceptors.
    Liu S; Hanzlik RP
    J Med Chem; 1992 Mar; 35(6):1067-75. PubMed ID: 1552501
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A re-appraisal of the structural basis of stereochemical recognition in papain. Insensitivity of binding-site-catalytic-site signalling to P2-chirality in a time-dependent inhibition.
    Templeton W; Kowlessur D; Thomas EW; Topham CM; Brocklehurst K
    Biochem J; 1990 Mar; 266(3):645-51. PubMed ID: 2327953
    [TBL] [Abstract][Full Text] [Related]  

  • 19. New non-peptidic inhibitors of papain derived from etacrynic acid.
    Kaeppler U; Schirmeister T
    Med Chem; 2005 Jul; 1(4):361-70. PubMed ID: 16789893
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Clarification of substrate specificity of papain by crystal analyses of complexes with covalent-type inhibitors.
    Matsumoto K; Murata M; Sumiya S; Kitamura K; Ishida T
    Biochim Biophys Acta; 1994 Oct; 1208(2):268-76. PubMed ID: 7947958
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.