These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

129 related articles for article (PubMed ID: 9416773)

  • 21. Structure and function of cytochromes P450: a comparative analysis of three crystal structures.
    Hasemann CA; Kurumbail RG; Boddupalli SS; Peterson JA; Deisenhofer J
    Structure; 1995 Jan; 3(1):41-62. PubMed ID: 7743131
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Structural basis of steroid binding and oxidation by the cytochrome P450 CYP109E1 from Bacillus megaterium.
    Jóźwik IK; Kiss FM; Gricman Ł; Abdulmughni A; Brill E; Zapp J; Pleiss J; Bernhardt R; Thunnissen AW
    FEBS J; 2016 Nov; 283(22):4128-4148. PubMed ID: 27686671
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Automated multiple analysis of protein structures: application to homology modeling of cytochromes P450.
    Jean P; Pothier J; Dansette PM; Mansuy D; Viari A
    Proteins; 1997 Jul; 28(3):388-404. PubMed ID: 9223185
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Molecular modeling-guided site-directed mutagenesis of cytochrome P450 2D6.
    de Graaf C; Oostenbrink C; Keizers PH; van Vugt-Lussenburg BM; van Waterschoot RA; Tschirret-Guth RA; Commandeur JN; Vermeulen NP
    Curr Drug Metab; 2007 Jan; 8(1):59-77. PubMed ID: 17266524
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Homology modeling of lanosterol 14alpha-demethylase of Candida albicans and Aspergillus fumigatus and insights into the enzyme-substrate Interactions.
    Sheng C; Zhang W; Zhang M; Song Y; Ji H; Zhu J; Yao J; Yu J; Yang S; Zhou Y; Zhu J; Lu J
    J Biomol Struct Dyn; 2004 Aug; 22(1):91-9. PubMed ID: 15214809
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Structural determinants of progesterone hydroxylation by cytochrome P450 2B5: the role of nonsubstrate recognition site residues.
    He YQ; Harlow GR; Szklarz GD; Halpert JR
    Arch Biochem Biophys; 1998 Feb; 350(2):333-9. PubMed ID: 9473309
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Structural flexibility and functional versatility of mammalian P450 enzymes.
    Negishi M; Uno T; Darden TA; Sueyoshi T; Pedersen LG
    FASEB J; 1996 May; 10(7):683-9. PubMed ID: 8635685
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Progress in cytochrome P450 active site modeling.
    Kemp CA; Maréchal JD; Sutcliffe MJ
    Arch Biochem Biophys; 2005 Jan; 433(2):361-8. PubMed ID: 15581592
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Modelling of three-dimensional structures of cytochromes P450 11B1 and 11B2.
    Belkina NV; Lisurek M; Ivanov AS; Bernhardt R
    J Inorg Biochem; 2001 Dec; 87(4):197-207. PubMed ID: 11744057
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Modeling and mutagenesis of the active site of human P450c17.
    Lin D; Zhang LH; Chiao E; Miller WL
    Mol Endocrinol; 1994 Mar; 8(3):392-402. PubMed ID: 8015556
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Structure-function analysis of human cytochrome P-450 2B6 using a novel substrate, site-directed mutagenesis, and molecular modeling.
    Domanski TL; Schultz KM; Roussel F; Stevens JC; Halpert JR
    J Pharmacol Exp Ther; 1999 Sep; 290(3):1141-7. PubMed ID: 10454488
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Combining in silico protein stability calculations with structure-function relationships to explore the effect of polymorphic variation on cytochrome P450 drug metabolism.
    Arendse L; Blundell TL; Blackburn J
    Curr Drug Metab; 2013 Sep; 14(7):745-63. PubMed ID: 23826828
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Structure-function analysis of cytochromes P450 2B.
    Zhao Y; Halpert JR
    Biochim Biophys Acta; 2007 Mar; 1770(3):402-12. PubMed ID: 16935426
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Peroxo-iron and oxenoid-iron species as alternative oxygenating agents in cytochrome P450-catalyzed reactions: switching by threonine-302 to alanine mutagenesis of cytochrome P450 2B4.
    Vaz AD; Pernecky SJ; Raner GM; Coon MJ
    Proc Natl Acad Sci U S A; 1996 May; 93(10):4644-8. PubMed ID: 8643457
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Ketoconazole-induced conformational changes in the active site of cytochrome P450eryF.
    Cupp-Vickery JR; Garcia C; Hofacre A; McGee-Estrada K
    J Mol Biol; 2001 Aug; 311(1):101-10. PubMed ID: 11469860
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Construction and evaluation of a three-dimensional structure of cytochrome P450choP enzyme (CYP105C1).
    Chang YT; Loew GH
    Protein Eng; 1996 Sep; 9(9):755-66. PubMed ID: 8888141
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Structure and function of cytochromes P450 2B: from mechanism-based inactivators to X-ray crystal structures and back.
    Halpert JR
    Drug Metab Dispos; 2011 Jul; 39(7):1113-21. PubMed ID: 21502194
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Use of directed evolution of mammalian cytochromes P450 for investigating the molecular basis of enzyme function and generating novel biocatalysts.
    Kumar S; Halpert JR
    Biochem Biophys Res Commun; 2005 Dec; 338(1):456-64. PubMed ID: 16126165
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Conformational states of cytochrome P450cam revealed by trapping of synthetic molecular wires.
    Hays AM; Dunn AR; Chiu R; Gray HB; Stout CD; Goodin DB
    J Mol Biol; 2004 Nov; 344(2):455-69. PubMed ID: 15522298
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Essential requirements for substrate binding affinity and selectivity toward human CYP2 family enzymes.
    Lewis DF
    Arch Biochem Biophys; 2003 Jan; 409(1):32-44. PubMed ID: 12464242
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.