These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

100 related articles for article (PubMed ID: 9416969)

  • 1. Effects on DNA integrity and apoptosis induction by a novel antitumor sesquiterpene drug, 6-hydroxymethylacylfulvene (HMAF, MGI 114).
    Woynarowski JM; Napier C; Koester SK; Chen SF; Troyer D; Chapman W; MacDonald JR
    Biochem Pharmacol; 1997 Dec; 54(11):1181-93. PubMed ID: 9416969
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Drug uptake and cellular targets of hydroxymethylacylfulvene (HMAF).
    Herzig MC; Arnett B; MacDonald JR; Woynarowski JM
    Biochem Pharmacol; 1999 Jul; 58(2):217-25. PubMed ID: 10423161
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Differential cytotoxicity and induction of apoptosis in tumor and normal cells by hydroxymethylacylfulvene (HMAF).
    Woynarowska BA; Woynarowski JM; Herzig MC; Roberts K; Higdon AL; MacDonald JR
    Biochem Pharmacol; 2000 May; 59(10):1217-26. PubMed ID: 10736422
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeting apoptosis by hydroxymethylacylfulvene in combination with gamma radiation in prostate tumor cells.
    Woynarowska BA; Roberts K; Woynarowski JM; MacDonald JR; Herman TS
    Radiat Res; 2000 Oct; 154(4):429-38. PubMed ID: 11023607
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Antitumor activity of MGI 114 (6-hydroxymethylacylfulvene, HMAF), a semisynthetic derivative of illudin S, against adult and pediatric human tumor colony-forming units.
    Hidalgo M; Izbicka E; Eckhardt SG; MacDonald JR; Cerna C; Gomez L; Rowinsky EK; Weitman SD; Von Hoff DD
    Anticancer Drugs; 1999 Oct; 10(9):837-44. PubMed ID: 10587294
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Apoptosis induction by the dual-action DNA- and protein-reactive antitumor drug irofulven is largely Bcl-2-independent.
    Herzig MC; Trevino AV; Liang H; Salinas R; Waters SJ; MacDonald JR; Woynarowska BA; Woynarowski JM
    Biochem Pharmacol; 2003 Feb; 65(4):503-13. PubMed ID: 12566077
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Efficacy of HMAF (MGI-114) in the MV522 metastatic lung carcinoma xenograft model nonresponsive to traditional anticancer agents.
    Kelner MJ; McMorris TC; Estes L; Wang W; Samson KM; Taetle R
    Invest New Drugs; 1996; 14(2):161-7. PubMed ID: 8913837
    [TBL] [Abstract][Full Text] [Related]  

  • 8. BRCA1 contributes to cell cycle arrest and chemoresistance in response to the anticancer agent irofulven.
    Wiltshire T; Senft J; Wang Y; Konat GW; Wenger SL; Reed E; Wang W
    Mol Pharmacol; 2007 Apr; 71(4):1051-60. PubMed ID: 17229870
    [TBL] [Abstract][Full Text] [Related]  

  • 9. DNA strand breaks and apoptosis induced by oxaliplatin in cancer cells.
    Faivre S; Chan D; Salinas R; Woynarowska B; Woynarowski JM
    Biochem Pharmacol; 2003 Jul; 66(2):225-37. PubMed ID: 12826265
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Irofulven induces apoptosis in breast cancer cells regardless of caspase-3 status.
    Herzig MC; Liang H; Johnson AE; Woynarowska B; Woynarowski JM
    Breast Cancer Res Treat; 2002 Jan; 71(2):133-43. PubMed ID: 11883439
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterization of MGI 114 (HMAF) histiospecific toxicity in human tumor cell lines.
    Kelner MJ; McMorris TC; Montoya MA; Estes L; Uglik SF; Rutherford M; Samson KM; Bagnell RD; Taetle R
    Cancer Chemother Pharmacol; 1999; 44(3):235-40. PubMed ID: 10453725
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Preclinical antitumor activity of 6-hydroxymethylacylfulvene, a semisynthetic derivative of the mushroom toxin illudin S.
    MacDonald JR; Muscoplat CC; Dexter DL; Mangold GL; Chen SF; Kelner MJ; McMorris TC; Von Hoff DD
    Cancer Res; 1997 Jan; 57(2):279-83. PubMed ID: 9000568
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Apoptotic and non-apoptotic cell death induced by cis and trans analogues of a novel ammine(cyclohexylamine)dihydroxodichloroplatinum(IV) complex.
    O'Neill CF; Ormerod MG; Robertson D; Titley JC; Cumber-Walsweer Y; Kelland LR
    Br J Cancer; 1996 Oct; 74(7):1037-45. PubMed ID: 8855971
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Fludarabine-mediated repair inhibition of cisplatin-induced DNA lesions in human chronic myelogenous leukemia-blast crisis K562 cells: induction of synergistic cytotoxicity independent of reversal of apoptosis resistance.
    Li L; Keating MJ; Plunkett W; Yang LY
    Mol Pharmacol; 1997 Nov; 52(5):798-806. PubMed ID: 9351970
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Anti-tumour compounds illudin S and Irofulven induce DNA lesions ignored by global repair and exclusively processed by transcription- and replication-coupled repair pathways.
    Jaspers NG; Raams A; Kelner MJ; Ng JM; Yamashita YM; Takeda S; McMorris TC; Hoeijmakers JH
    DNA Repair (Amst); 2002 Dec; 1(12):1027-38. PubMed ID: 12531012
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The cell cycle related differences in susceptibility of HL-60 cells to apoptosis induced by various antitumor agents.
    Gorczyca W; Gong J; Ardelt B; Traganos F; Darzynkiewicz Z
    Cancer Res; 1993 Jul; 53(13):3186-92. PubMed ID: 8319228
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cell cycle effects and induction of premitotic apoptosis by irofulven in synchronized cancer cells.
    Woynarowski JM; Woynarowska BA; Trevino AV; Salinas R; Herman TS; Waters SJ; Macdonald JR
    Cancer Biol Ther; 2004 Nov; 3(11):1137-42; discussion 1143-4. PubMed ID: 15467441
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Anti-leukemic action of the novel agent MGI 114 (HMAF) and synergistic action with topotecan.
    Kelner MJ; McMorris TC; Estes L; Samson KM; Trani NA; MacDonald JR
    Leukemia; 2000 Jan; 14(1):136-41. PubMed ID: 10637489
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Irofulven (6-hydroxymethylacylfulvene, MGI 114) induces caspase 8 and 9-mediated apoptosis in human pancreatic adenocarcinoma cells.
    Wang W; Waters SJ; MacDonald JR; Von Hoff DD; Strodel WE; Miller AR
    Anticancer Res; 2001; 21(3B):1789-94. PubMed ID: 11497260
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discovery and development of sesquiterpenoid derived hydroxymethylacylfulvene: a new anticancer drug.
    McMorris TC
    Bioorg Med Chem; 1999 May; 7(5):881-6. PubMed ID: 10400341
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.