BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

151 related articles for article (PubMed ID: 9417068)

  • 1. Blood coagulation factor IX residues Glu78 and Arg94 provide a link between both epidermal growth factor-like domains that is crucial in the interaction with factor VIII light chain.
    Christophe OD; Lenting PJ; Kolkman JA; Brownlee GG; Mertens K
    J Biol Chem; 1998 Jan; 273(1):222-7. PubMed ID: 9417068
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ca2+ binding to the first epidermal growth factor-like domain of human blood coagulation factor IX promotes enzyme activity and factor VIII light chain binding.
    Lenting PJ; Christophe OD; Maat H; Rees DJ; Mertens K
    J Biol Chem; 1996 Oct; 271(41):25332-7. PubMed ID: 8810297
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The sequence Glu1811-Lys1818 of human blood coagulation factor VIII comprises a binding site for activated factor IX.
    Lenting PJ; van de Loo JW; Donath MJ; van Mourik JA; Mertens K
    J Biol Chem; 1996 Jan; 271(4):1935-40. PubMed ID: 8567641
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hydrophobic contact between the two epidermal growth factor-like domains of blood coagulation factor IX contributes to enzymatic activity.
    Celie PH; Lenting PJ; Mertens K
    J Biol Chem; 2000 Jan; 275(1):229-34. PubMed ID: 10617609
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Insertion loop 256-268 in coagulation factor IX restricts enzymatic activity in the absence but not in the presence of factor VIII.
    Kolkman JA; Mertens K
    Biochemistry; 2000 Jun; 39(25):7398-405. PubMed ID: 10858287
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The connecting segment between both epidermal growth factor-like domains in blood coagulation factor IX contributes to stimulation by factor VIIIa and its isolated A2 domain.
    Celie PH; Van Stempvoort G; Fribourg C; Schurgers LJ; Lenting PJ; Mertens K
    J Biol Chem; 2002 Jun; 277(23):20214-20. PubMed ID: 11925427
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cleavage at arginine 145 in human blood coagulation factor IX converts the zymogen into a factor VIII binding enzyme.
    Lenting PJ; ter Maat H; Clijsters PP; Donath MJ; van Mourik JA; Mertens K
    J Biol Chem; 1995 Jun; 270(25):14884-90. PubMed ID: 7797466
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of functionally important residues of the epidermal growth factor-2 domain of factor IX by alanine-scanning mutagenesis. Residues Asn(89)-Gly(93) are critical for binding factor VIIIa.
    Chang YJ; Wu HL; Hamaguchi N; Hsu YC; Lin SW
    J Biol Chem; 2002 Jul; 277(28):25393-9. PubMed ID: 11960977
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Factor IX Fukuoka. Substitution of ASN92 by His in the second epidermal growth factor-like domain results in defective interaction with factors VIIa/X.
    Nishimura H; Takeya H; Miyata T; Suehiro K; Okamura T; Niho Y; Iwanaga S
    J Biol Chem; 1993 Nov; 268(32):24041-6. PubMed ID: 8226948
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The epidermal growth factor-like domains of factor IX. Effect on blood clotting and endothelial cell binding of a fragment containing the epidermal growth factor-like domains linked to the gamma-carboxyglutamic acid region.
    Astermark J; Stenflo J
    J Biol Chem; 1991 Feb; 266(4):2438-43. PubMed ID: 1989995
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Baculovirus-mediated expression of the epidermal growth factor-like modules of human factor IX fused to the factor XIIIa transamidation site in fibronectin. Evidence for a direct interaction between the NH2-terminal epidermal growth factor-like module of factor IXa beta and factor X.
    Astermark J; Sottile J; Mosher DF; Stenflo J
    J Biol Chem; 1994 Feb; 269(5):3690-7. PubMed ID: 7906269
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Residues Phe342-Asn346 of activated coagulation factor IX contribute to the interaction with low density lipoprotein receptor-related protein.
    Rohlena J; Kolkman JA; Boertjes RC; Mertens K; Lenting PJ
    J Biol Chem; 2003 Mar; 278(11):9394-401. PubMed ID: 12522212
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterization of the functional defect in factor IX Alabama. Evidence for a conformational change due to high affinity calcium binding in the first epidermal growth factor domain.
    McCord DM; Monroe DM; Smith KJ; Roberts HR
    J Biol Chem; 1990 Jun; 265(18):10250-4. PubMed ID: 2355000
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Tyrosine 69 of the first epidermal growth factor-like domain of human factor IX is essential for clotting activity.
    Hughes PE; Morgan G; Rooney EK; Brownlee GG; Handford P
    J Biol Chem; 1993 Aug; 268(24):17727-33. PubMed ID: 8349658
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Coordinate binding studies of the substrate (factor X) with the cofactor (factor VIII) in the assembly of the factor X activating complex on the activated platelet surface.
    Ahmad SS; Walsh PN
    Biochemistry; 2002 Sep; 41(37):11269-76. PubMed ID: 12220193
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hemophilia B with mutations at glycine-48 of factor IX exhibited delayed activation by the factor VIIa-tissue factor complex.
    Wu PC; Hamaguchi N; Yu YS; Shen MC; Lin SW
    Thromb Haemost; 2000 Oct; 84(4):626-34. PubMed ID: 11057861
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The N-terminal epidermal growth factor-like domain of coagulation factor IX. Probing its functions in the activation of factor IX and factor X with a monoclonal antibody.
    Persson KE; Villoutreix BO; Thämlitz AM; Knobe KE; Stenflo J
    J Biol Chem; 2002 Sep; 277(38):35616-24. PubMed ID: 12105230
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The role of the first growth factor domain of human factor IXa in binding to platelets and in factor X activation.
    Ahmad SS; Rawala-Sheikh R; Cheung WF; Stafford DW; Walsh PN
    J Biol Chem; 1992 Apr; 267(12):8571-6. PubMed ID: 1569103
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural integrity of the gamma-carboxyglutamic acid domain of human blood coagulation factor IXa Is required for its binding to cofactor VIIIa.
    Larson PJ; Stanfield-Oakley SA; VanDusen WJ; Kasper CK; Smith KJ; Monroe DM; High KA
    J Biol Chem; 1996 Feb; 271(7):3869-76. PubMed ID: 8632006
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The interface between the EGF2 domain and the protease domain in blood coagulation factor IX contributes to factor VIII binding and factor X activation.
    Fribourg C; Meijer AB; Mertens K
    Biochemistry; 2006 Sep; 45(35):10777-85. PubMed ID: 16939230
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.