BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

173 related articles for article (PubMed ID: 9417098)

  • 1. Replacements of single basic amino acids in the pleckstrin homology domain of phospholipase C-delta1 alter the ligand binding, phospholipase activity, and interaction with the plasma membrane.
    Yagisawa H; Sakuma K; Paterson HF; Cheung R; Allen V; Hirata H; Watanabe Y; Hirata M; Williams RL; Katan M
    J Biol Chem; 1998 Jan; 273(1):417-24. PubMed ID: 9417098
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phospholipase C-delta1 contains a functional nuclear export signal sequence.
    Yamaga M; Fujii M; Kamata H; Hirata H; Yagisawa H
    J Biol Chem; 1999 Oct; 274(40):28537-41. PubMed ID: 10497218
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A single amino acid substitution in the pleckstrin homology domain of phospholipase C delta1 enhances the rate of substrate hydrolysis.
    Bromann PA; Boetticher EE; Lomasney JW
    J Biol Chem; 1997 Jun; 272(26):16240-6. PubMed ID: 9195925
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Specific and high-affinity binding of inositol phosphates to an isolated pleckstrin homology domain.
    Lemmon MA; Ferguson KM; O'Brien R; Sigler PB; Schlessinger J
    Proc Natl Acad Sci U S A; 1995 Nov; 92(23):10472-6. PubMed ID: 7479822
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Involvement of EF hand motifs in the Ca(2+)-dependent binding of the pleckstrin homology domain to phosphoinositides.
    Yamamoto T; Takeuchi H; Kanematsu T; Allen V; Yagisawa H; Kikkawa U; Watanabe Y; Nakasima A; Katan M; Hirata M
    Eur J Biochem; 1999 Oct; 265(1):481-90. PubMed ID: 10491207
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Domain organization of p130, PLC-related catalytically inactive protein, and structural basis for the lack of enzyme activity.
    Kanematsu T; Yoshimura K; Hidaka K; Takeuchi H; Katan M; Hirata M
    Eur J Biochem; 2000 May; 267(9):2731-7. PubMed ID: 10785396
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phosphatidylinositol 4,5-bisphosphate binding to the pleckstrin homology domain of phospholipase C-delta1 enhances enzyme activity.
    Lomasney JW; Cheng HF; Wang LP; Kuan Y; Liu S; Fesik SW; King K
    J Biol Chem; 1996 Oct; 271(41):25316-26. PubMed ID: 8810295
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Phosphoinositide binding specificity among phospholipase C isozymes as determined by photo-cross-linking to novel substrate and product analogs.
    Tall E; Dormán G; Garcia P; Runnels L; Shah S; Chen J; Profit A; Gu QM; Chaudhary A; Prestwich GD; Rebecchi MJ
    Biochemistry; 1997 Jun; 36(23):7239-48. PubMed ID: 9188725
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Membrane association of a new inositol 1,4,5-trisphosphate binding protein, p130 is not dependent on the pleckstrin homology domain.
    Takeuchi H; Kanematsu T; Misumi Y; Hirata M
    Chem Phys Lipids; 1999 Apr; 98(1-2):35-47. PubMed ID: 10358926
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Phospholipase C delta 1 requires a pleckstrin homology domain for interaction with the plasma membrane.
    Paterson HF; Savopoulos JW; Perisic O; Cheung R; Ellis MV; Williams RL; Katan M
    Biochem J; 1995 Dec; 312 ( Pt 3)(Pt 3):661-6. PubMed ID: 8554502
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Expression and characterization of an inositol 1,4,5-trisphosphate binding domain of phosphatidylinositol-specific phospholipase C-delta 1.
    Yagisawa H; Hirata M; Kanematsu T; Watanabe Y; Ozaki S; Sakuma K; Tanaka H; Yabuta N; Kamata H; Hirata H
    J Biol Chem; 1994 Aug; 269(31):20179-88. PubMed ID: 8051106
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A new inositol 1,4,5-trisphosphate binding protein similar to phospholipase C-delta 1.
    Kanematsu T; Misumi Y; Watanabe Y; Ozaki S; Koga T; Iwanaga S; Ikehara Y; Hirata M
    Biochem J; 1996 Jan; 313 ( Pt 1)(Pt 1):319-25. PubMed ID: 8546702
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mutation in the pleckstrin homology domain of the human phospholipase C-delta 1 gene is associated with loss of function.
    Shimohama S; Kamiya S; Fujii M; Ogawa T; Kanamori M; Kawamata J; Imura T; Taniguchi T; Yagisawa H
    Biochem Biophys Res Commun; 1998 Apr; 245(3):722-8. PubMed ID: 9588182
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Localization of a high-affinity inositol 1,4,5-trisphosphate/inositol 1,4,5,6-tetrakisphosphate binding domain to the pleckstrin homology module of a new 130 kDa protein: characterization of the determinants of structural specificity.
    Takeuchi H; Kanematsu T; Misumi Y; Yaakob HB; Yagisawa H; Ikehara Y; Watanabe Y; Tan Z; Shears SB; Hirata M
    Biochem J; 1996 Sep; 318 ( Pt 2)(Pt 2):561-8. PubMed ID: 8809047
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The pleckstrin homology domain of phospholipase C-delta 1 binds with high affinity to phosphatidylinositol 4,5-bisphosphate in bilayer membranes.
    Garcia P; Gupta R; Shah S; Morris AJ; Rudge SA; Scarlata S; Petrova V; McLaughlin S; Rebecchi MJ
    Biochemistry; 1995 Dec; 34(49):16228-34. PubMed ID: 8519781
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Real-time visualization of PH domain-dependent translocation of phospholipase C-delta1 in renal epithelial cells (MDCK): response to hypo-osmotic stress.
    Fujii M; Ohtsubo M; Ogawa T; Kamata H; Hirata H; Yagisawa H
    Biochem Biophys Res Commun; 1999 Jan; 254(2):284-91. PubMed ID: 9918830
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Membrane targeting of C2 domains of phospholipase C-delta isoforms.
    Ananthanarayanan B; Das S; Rhee SG; Murray D; Cho W
    J Biol Chem; 2002 Feb; 277(5):3568-75. PubMed ID: 11706040
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The pleckstrin homology domain of phospholipase Cbeta transmits enzymatic activation through modulation of the membrane-domain orientation.
    Drin G; Douguet D; Scarlata S
    Biochemistry; 2006 May; 45(18):5712-24. PubMed ID: 16669615
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Binding of PLCdelta1PH-GFP to PtdIns(4,5)P2 prevents inhibition of phospholipase C-mediated hydrolysis of PtdIns(4,5)P2 by neomycin.
    Wang C; Du XN; Jia QZ; Zhang HL
    Acta Pharmacol Sin; 2005 Dec; 26(12):1485-91. PubMed ID: 16297348
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Membrane activity of the phospholipase C-delta1 pleckstrin homology (PH) domain.
    Flesch FM; Yu JW; Lemmon MA; Burger KN
    Biochem J; 2005 Jul; 389(Pt 2):435-41. PubMed ID: 15755258
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.