128 related articles for article (PubMed ID: 9425092)
1. Characterization of Glu350 as a critical residue involved in the N-terminal amine binding site of aminopeptidase N (EC 3.4.11.2): insights into its mechanism of action.
Luciani N; Marie-Claire C; Ruffet E; Beaumont A; Roques BP; Fournié-Zaluski MC
Biochemistry; 1998 Jan; 37(2):686-92. PubMed ID: 9425092
[TBL] [Abstract][Full Text] [Related]
2. Contribution of molecular modeling and site-directed mutagenesis to the identification of a new residue, glutamate 215, involved in the exopeptidase specificity of aminopeptidase A.
Rozenfeld R; Iturrioz X; Okada M; Maigret B; Llorens-Cortes C
Biochemistry; 2003 Dec; 42(50):14785-93. PubMed ID: 14674752
[TBL] [Abstract][Full Text] [Related]
3. Site-directed mutagenesis of active site glutamate-217 in mouse adenosine deaminase.
Mohamedali KA; Kurz LC; Rudolph FB
Biochemistry; 1996 Feb; 35(5):1672-80. PubMed ID: 8634299
[TBL] [Abstract][Full Text] [Related]
4. Role of active-site residues of dispersin B, a biofilm-releasing beta-hexosaminidase from a periodontal pathogen, in substrate hydrolysis.
Manuel SG; Ragunath C; Sait HB; Izano EA; Kaplan JB; Ramasubbu N
FEBS J; 2007 Nov; 274(22):5987-99. PubMed ID: 17949435
[TBL] [Abstract][Full Text] [Related]
5. Novel inhibitor for prolyl tripeptidyl aminopeptidase from Porphyromonas gingivalis and details of substrate-recognition mechanism.
Xu Y; Nakajima Y; Ito K; Zheng H; Oyama H; Heiser U; Hoffmann T; Gärtner UT; Demuth HU; Yoshimoto T
J Mol Biol; 2008 Jan; 375(3):708-19. PubMed ID: 18042490
[TBL] [Abstract][Full Text] [Related]
6. Mutational analysis of the oligosaccharide recognition site at the active site of Escherichia coli maltodextrin phosphorylase.
Drueckes P; Boeck B; Palm D; Schinzel R
Biochemistry; 1996 May; 35(21):6727-34. PubMed ID: 8639623
[TBL] [Abstract][Full Text] [Related]
7. Evidence by site-directed mutagenesis that arginine 203 of thermolysin and arginine 717 of neprilysin (neutral endopeptidase) play equivalent critical roles in substrate hydrolysis and inhibitor binding.
Marie-Claire C; Ruffet E; Antonczak S; Beaumont A; O'Donohue M; Roques BP; Fournié-Zaluski MC
Biochemistry; 1997 Nov; 36(45):13938-45. PubMed ID: 9374873
[TBL] [Abstract][Full Text] [Related]
8. Aminopeptidase A, which generates one of the main effector peptides of the brain renin-angiotensin system, angiotensin III, has a key role in central control of arterial blood pressure.
Reaux A; Iturrioz X; Vazeux G; Fournie-Zaluski MC; David C; Roques BP; Corvol P; Llorens-Cortes C
Biochem Soc Trans; 2000; 28(4):435-40. PubMed ID: 10961935
[TBL] [Abstract][Full Text] [Related]
9. Porcine recombinant dihydropyrimidine dehydrogenase: comparison of the spectroscopic and catalytic properties of the wild-type and C671A mutant enzymes.
Rosenbaum K; Jahnke K; Curti B; Hagen WR; Schnackerz KD; Vanoni MA
Biochemistry; 1998 Dec; 37(50):17598-609. PubMed ID: 9860876
[TBL] [Abstract][Full Text] [Related]
10. A glutamate residue contributes to the exopeptidase specificity in aminopeptidase A.
Vazeux G; Iturrioz X; Corvol P; Llorens-Cortes C
Biochem J; 1998 Sep; 334 ( Pt 2)(Pt 2):407-13. PubMed ID: 9716499
[TBL] [Abstract][Full Text] [Related]
11. Molecular mechanism of the enterococcal aminoglycoside 6'-N-acetyltransferase': role of GNAT-conserved residues in the chemistry of antibiotic inactivation.
Draker KA; Wright GD
Biochemistry; 2004 Jan; 43(2):446-54. PubMed ID: 14717599
[TBL] [Abstract][Full Text] [Related]
12. Probing the mechanism of hamster arylamine N-acetyltransferase 2 acetylation by active site modification, site-directed mutagenesis, and pre-steady state and steady state kinetic studies.
Wang H; Vath GM; Gleason KJ; Hanna PE; Wagner CR
Biochemistry; 2004 Jun; 43(25):8234-46. PubMed ID: 15209520
[TBL] [Abstract][Full Text] [Related]
13. Proteolytic fragmentation reveals the oligomeric and domain structure of porcine aminopeptidase A.
Hesp JR; Hooper NM
Biochemistry; 1997 Mar; 36(10):3000-7. PubMed ID: 9062131
[TBL] [Abstract][Full Text] [Related]
14. Structure/function analysis of a dUTPase: catalytic mechanism of a potential chemotherapeutic target.
Harris JM; McIntosh EM; Muscat GE
J Mol Biol; 1999 Apr; 288(2):275-87. PubMed ID: 10329142
[TBL] [Abstract][Full Text] [Related]
15. Identification of an inhibitor binding site of poly(ADP-ribose) glycohydrolase.
Koh DW; Patel CN; Ramsinghani S; Slama JT; Oliveira MA; Jacobson MK
Biochemistry; 2003 May; 42(17):4855-63. PubMed ID: 12718526
[TBL] [Abstract][Full Text] [Related]
16. Site-directed mutagenesis of the active site of diacylglycerol kinase alpha: calcium and phosphatidylserine stimulate enzyme activity via distinct mechanisms.
Abe T; Lu X; Jiang Y; Boccone CE; Qian S; Vattem KM; Wek RC; Walsh JP
Biochem J; 2003 Nov; 375(Pt 3):673-80. PubMed ID: 12908872
[TBL] [Abstract][Full Text] [Related]
17. Sterol methyltransferase: functional analysis of highly conserved residues by site-directed mutagenesis.
Nes WD; Jayasimha P; Zhou W; Kanagasabai R; Jin C; Jaradat TT; Shaw RW; Bujnicki JM
Biochemistry; 2004 Jan; 43(2):569-76. PubMed ID: 14717613
[TBL] [Abstract][Full Text] [Related]
18. Structures of chitobiase mutants complexed with the substrate Di-N-acetyl-d-glucosamine: the catalytic role of the conserved acidic pair, aspartate 539 and glutamate 540.
Prag G; Papanikolau Y; Tavlas G; Vorgias CE; Petratos K; Oppenheim AB
J Mol Biol; 2000 Jul; 300(3):611-7. PubMed ID: 10884356
[TBL] [Abstract][Full Text] [Related]
19. The conserved methionine residue of the metzincins: a site-directed mutagenesis study.
Hege T; Baumann U
J Mol Biol; 2001 Nov; 314(2):181-6. PubMed ID: 11718552
[TBL] [Abstract][Full Text] [Related]
20. Implication by site-directed mutagenesis of Arg314 and Tyr316 in the coenzyme site of pig mitochondrial NADP-dependent isocitrate dehydrogenase.
Lee P; Colman RF
Arch Biochem Biophys; 2002 May; 401(1):81-90. PubMed ID: 12054490
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]