BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

215 related articles for article (PubMed ID: 9427629)

  • 1. Regulation of the MAP kinase pathway by mammalian Ksr through direct interaction with MEK and ERK.
    Yu W; Fantl WJ; Harrowe G; Williams LT
    Curr Biol; 1998 Jan; 8(1):56-64. PubMed ID: 9427629
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Murine Ksr interacts with MEK and inhibits Ras-induced transformation.
    Denouel-Galy A; Douville EM; Warne PH; Papin C; Laugier D; Calothy G; Downward J; Eychène A
    Curr Biol; 1998 Jan; 8(1):46-55. PubMed ID: 9427625
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The kinase suppressor of Ras (KSR) modulates growth factor and Ras signaling by uncoupling Elk-1 phosphorylation from MAP kinase activation.
    Sugimoto T; Stewart S; Han M; Guan KL
    EMBO J; 1998 Mar; 17(6):1717-27. PubMed ID: 9501093
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Kinase suppressor of Ras inhibits the activation of extracellular ligand-regulated (ERK) mitogen-activated protein (MAP) kinase by growth factors, activated Ras, and Ras effectors.
    Joneson T; Fulton JA; Volle DJ; Chaika OV; Bar-Sagi D; Lewis RE
    J Biol Chem; 1998 Mar; 273(13):7743-8. PubMed ID: 9516483
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Kinase suppressor of Ras forms a multiprotein signaling complex and modulates MEK localization.
    Stewart S; Sundaram M; Zhang Y; Lee J; Han M; Guan KL
    Mol Cell Biol; 1999 Aug; 19(8):5523-34. PubMed ID: 10409742
    [TBL] [Abstract][Full Text] [Related]  

  • 6. MEK-2, a Caenorhabditis elegans MAP kinase kinase, functions in Ras-mediated vulval induction and other developmental events.
    Wu Y; Han M; Guan KL
    Genes Dev; 1995 Mar; 9(6):742-55. PubMed ID: 7729690
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Kinase suppressor of ras is necessary for tumor necrosis factor alpha activation of extracellular signal-regulated kinase/mitogen-activated protein kinase in intestinal epithelial cells.
    Yan F; Polk DB
    Cancer Res; 2001 Feb; 61(3):963-9. PubMed ID: 11221891
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Signaling molecules involved in coupling growth hormone receptor to mitogen-activated protein kinase activation.
    Vanderkuur JA; Butch ER; Waters SB; Pessin JE; Guan KL; Carter-Su C
    Endocrinology; 1997 Oct; 138(10):4301-7. PubMed ID: 9322943
    [TBL] [Abstract][Full Text] [Related]  

  • 9. C. elegans ksr-1 and ksr-2 have both unique and redundant functions and are required for MPK-1 ERK phosphorylation.
    Ohmachi M; Rocheleau CE; Church D; Lambie E; Schedl T; Sundaram MV
    Curr Biol; 2002 Mar; 12(5):427-33. PubMed ID: 11882296
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lipopolysaccharide signals activation of tumor necrosis factor biosynthesis through the ras/raf-1/MEK/MAPK pathway.
    Geppert TD; Whitehurst CE; Thompson P; Beutler B
    Mol Med; 1994 Nov; 1(1):93-103. PubMed ID: 8790605
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Comparative effects of insulin on the activation of the Raf/Mos-dependent MAP kinase cascade in vitellogenic versus postvitellogenic Xenopus oocytes.
    Chesnel F; Bonnec G; Tardivel A; Boujard D
    Dev Biol; 1997 Aug; 188(1):122-33. PubMed ID: 9245517
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Activation of MEK-1 and SEK-1 by Tpl-2 proto-oncoprotein, a novel MAP kinase kinase kinase.
    Salmeron A; Ahmad TB; Carlile GW; Pappin D; Narsimhan RP; Ley SC
    EMBO J; 1996 Feb; 15(4):817-26. PubMed ID: 8631303
    [TBL] [Abstract][Full Text] [Related]  

  • 13. KSR is a scaffold required for activation of the ERK/MAPK module.
    Roy F; Laberge G; Douziech M; Ferland-McCollough D; Therrien M
    Genes Dev; 2002 Feb; 16(4):427-38. PubMed ID: 11850406
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activated Ki-Ras suppresses 12-O-tetradecanoylphorbol-13-acetate-induced activation of the c-Jun NH2-terminal kinase pathway in human colon cancer cells.
    Okumura K; Shirasawa S; Nishioka M; Sasazuki T
    Cancer Res; 1999 May; 59(10):2445-50. PubMed ID: 10344756
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synergistic activation by Ras and 14-3-3 protein of a mitogen-activated protein kinase kinase kinase named Ras-dependent extracellular signal-regulated kinase kinase stimulator.
    Shimizu K; Kuroda S; Yamamori B; Matsuda S; Kaibuchi K; Yamauchi T; Isobe T; Irie K; Matsumoto K; Takai Y
    J Biol Chem; 1994 Sep; 269(37):22917-20. PubMed ID: 8083186
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of constitutive and ras-inducible phosphorylation sites of KSR: implications for 14-3-3 binding, mitogen-activated protein kinase binding, and KSR overexpression.
    Cacace AM; Michaud NR; Therrien M; Mathes K; Copeland T; Rubin GM; Morrison DK
    Mol Cell Biol; 1999 Jan; 19(1):229-40. PubMed ID: 9858547
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The protein kinase KSR interacts with 14-3-3 protein and Raf.
    Xing H; Kornfeld K; Muslin AJ
    Curr Biol; 1997 May; 7(5):294-300. PubMed ID: 9115393
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Kinase suppressor of Ras (KSR) is a scaffold which facilitates mitogen-activated protein kinase activation in vivo.
    Nguyen A; Burack WR; Stock JL; Kortum R; Chaika OV; Afkarian M; Muller WJ; Murphy KM; Morrison DK; Lewis RE; McNeish J; Shaw AS
    Mol Cell Biol; 2002 May; 22(9):3035-45. PubMed ID: 11940661
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A human homolog of the yeast Ssk2/Ssk22 MAP kinase kinase kinases, MTK1, mediates stress-induced activation of the p38 and JNK pathways.
    Takekawa M; Posas F; Saito H
    EMBO J; 1997 Aug; 16(16):4973-82. PubMed ID: 9305639
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of a novel human kinase supporter of Ras (hKSR-2) that functions as a negative regulator of Cot (Tpl2) signaling.
    Channavajhala PL; Wu L; Cuozzo JW; Hall JP; Liu W; Lin LL; Zhang Y
    J Biol Chem; 2003 Nov; 278(47):47089-97. PubMed ID: 12975377
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.