BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

459 related articles for article (PubMed ID: 9430646)

  • 1. Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.
    Roth J; Dobbelstein M; Freedman DA; Shenk T; Levine AJ
    EMBO J; 1998 Jan; 17(2):554-64. PubMed ID: 9430646
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A comparison of the activity, sequence specificity, and CRM1-dependence of different nuclear export signals.
    Henderson BR; Eleftheriou A
    Exp Cell Res; 2000 Apr; 256(1):213-24. PubMed ID: 10739668
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Nucleocytoplasmic shuttling of oncoprotein Hdm2 is required for Hdm2-mediated degradation of p53.
    Tao W; Levine AJ
    Proc Natl Acad Sci U S A; 1999 Mar; 96(6):3077-80. PubMed ID: 10077639
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Nuclear and cytoplasmic degradation of endogenous p53 and HDM2 occurs during down-regulation of the p53 response after multiple types of DNA damage.
    Joseph TW; Zaika A; Moll UM
    FASEB J; 2003 Sep; 17(12):1622-30. PubMed ID: 12958168
    [TBL] [Abstract][Full Text] [Related]  

  • 5. MEK-ERK signaling controls Hdm2 oncoprotein expression by regulating hdm2 mRNA export to the cytoplasm.
    Phelps M; Phillips A; Darley M; Blaydes JP
    J Biol Chem; 2005 Apr; 280(17):16651-8. PubMed ID: 15723837
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cocompartmentalization of p53 and Mdm2 is a major determinant for Mdm2-mediated degradation of p53.
    Xirodimas DP; Stephen CW; Lane DP
    Exp Cell Res; 2001 Oct; 270(1):66-77. PubMed ID: 11597128
    [TBL] [Abstract][Full Text] [Related]  

  • 7. An intact HDM2 RING-finger domain is required for nuclear exclusion of p53.
    Boyd SD; Tsai KY; Jacks T
    Nat Cell Biol; 2000 Sep; 2(9):563-8. PubMed ID: 10980695
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hdmx recruitment into the nucleus by Hdm2 is essential for its ability to regulate p53 stability and transactivation.
    Migliorini D; Danovi D; Colombo E; Carbone R; Pelicci PG; Marine JC
    J Biol Chem; 2002 Mar; 277(9):7318-23. PubMed ID: 11744695
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The adenovirus type 5 E1B-55K oncoprotein is a highly active shuttle protein and shuttling is independent of E4orf6, p53 and Mdm2.
    Krätzer F; Rosorius O; Heger P; Hirschmann N; Dobner T; Hauber J; Stauber RH
    Oncogene; 2000 Feb; 19(7):850-7. PubMed ID: 10702793
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Nuclear degradation of p53 occurs during down-regulation of the p53 response after DNA damage.
    Shirangi TR; Zaika A; Moll UM
    FASEB J; 2002 Mar; 16(3):420-2. PubMed ID: 11790725
    [TBL] [Abstract][Full Text] [Related]  

  • 11. An inhibitor of nuclear export activates the p53 response and induces the localization of HDM2 and p53 to U1A-positive nuclear bodies associated with the PODs.
    Laín S; Midgley C; Sparks A; Lane EB; Lane DP
    Exp Cell Res; 1999 May; 248(2):457-72. PubMed ID: 10222137
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ribosomal protein L11 negatively regulates oncoprotein MDM2 and mediates a p53-dependent ribosomal-stress checkpoint pathway.
    Zhang Y; Wolf GW; Bhat K; Jin A; Allio T; Burkhart WA; Xiong Y
    Mol Cell Biol; 2003 Dec; 23(23):8902-12. PubMed ID: 14612427
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pim-1 protein kinase is nuclear in Burkitt's lymphoma: nuclear localization is necessary for its biologic effects.
    Ionov Y; Le X; Tunquist BJ; Sweetenham J; Sachs T; Ryder J; Johnson T; Lilly MB; Kraft AS
    Anticancer Res; 2003; 23(1A):167-78. PubMed ID: 12680209
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A cis-acting peptide signal in human immunodeficiency virus type I Rev which inhibits nuclear entry of small proteins.
    Kubota S; Pomerantz RJ
    Oncogene; 1998 Apr; 16(14):1851-61. PubMed ID: 9583682
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Nucleocytoplasmic shuttling of p53 is essential for MDM2-mediated cytoplasmic degradation but not ubiquitination.
    O'Keefe K; Li H; Zhang Y
    Mol Cell Biol; 2003 Sep; 23(18):6396-405. PubMed ID: 12944468
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The MDM2 RING-finger domain is required to promote p53 nuclear export.
    Geyer RK; Yu ZK; Maki CG
    Nat Cell Biol; 2000 Sep; 2(9):569-73. PubMed ID: 10980696
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nuclear transport of human immunodeficiency virus type 1, visna virus, and equine infectious anemia virus Rev proteins: identification of a family of transferable nuclear export signals.
    Meyer BE; Meinkoth JL; Malim MH
    J Virol; 1996 Apr; 70(4):2350-9. PubMed ID: 8642662
    [TBL] [Abstract][Full Text] [Related]  

  • 18. MNK1 and EIF4E are downstream effectors of MEKs in the regulation of the nuclear export of HDM2 mRNA.
    Phillips A; Blaydes JP
    Oncogene; 2008 Mar; 27(11):1645-9. PubMed ID: 17828301
    [TBL] [Abstract][Full Text] [Related]  

  • 19. P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2.
    Tao W; Levine AJ
    Proc Natl Acad Sci U S A; 1999 Jun; 96(12):6937-41. PubMed ID: 10359817
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A p53 amino-terminal nuclear export signal inhibited by DNA damage-induced phosphorylation.
    Zhang Y; Xiong Y
    Science; 2001 Jun; 292(5523):1910-5. PubMed ID: 11397945
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.