BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

196 related articles for article (PubMed ID: 9430731)

  • 1. Ribosome-binding domain of eukaryotic initiation factor-2 kinase GCN2 facilitates translation control.
    Zhu S; Wek RC
    J Biol Chem; 1998 Jan; 273(3):1808-14. PubMed ID: 9430731
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The histidyl-tRNA synthetase-related sequence in the eIF-2 alpha protein kinase GCN2 interacts with tRNA and is required for activation in response to starvation for different amino acids.
    Wek SA; Zhu S; Wek RC
    Mol Cell Biol; 1995 Aug; 15(8):4497-506. PubMed ID: 7623840
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mutations activating the yeast eIF-2 alpha kinase GCN2: isolation of alleles altering the domain related to histidyl-tRNA synthetases.
    Ramirez M; Wek RC; Vazquez de Aldana CR; Jackson BM; Freeman B; Hinnebusch AG
    Mol Cell Biol; 1992 Dec; 12(12):5801-15. PubMed ID: 1448107
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Evidence that GCN1 and GCN20, translational regulators of GCN4, function on elongating ribosomes in activation of eIF2alpha kinase GCN2.
    Marton MJ; Vazquez de Aldana CR; Qiu H; Chakraburtty K; Hinnebusch AG
    Mol Cell Biol; 1997 Aug; 17(8):4474-89. PubMed ID: 9234705
    [TBL] [Abstract][Full Text] [Related]  

  • 5. GCN1, a translational activator of GCN4 in Saccharomyces cerevisiae, is required for phosphorylation of eukaryotic translation initiation factor 2 by protein kinase GCN2.
    Marton MJ; Crouch D; Hinnebusch AG
    Mol Cell Biol; 1993 Jun; 13(6):3541-56. PubMed ID: 8497269
    [TBL] [Abstract][Full Text] [Related]  

  • 6. GCN20, a novel ATP binding cassette protein, and GCN1 reside in a complex that mediates activation of the eIF-2 alpha kinase GCN2 in amino acid-starved cells.
    Vazquez de Aldana CR; Marton MJ; Hinnebusch AG
    EMBO J; 1995 Jul; 14(13):3184-99. PubMed ID: 7621831
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ribosome association of GCN2 protein kinase, a translational activator of the GCN4 gene of Saccharomyces cerevisiae.
    Ramirez M; Wek RC; Hinnebusch AG
    Mol Cell Biol; 1991 Jun; 11(6):3027-36. PubMed ID: 2038314
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A mammalian homologue of GCN2 protein kinase important for translational control by phosphorylation of eukaryotic initiation factor-2alpha.
    Sood R; Porter AC; Olsen DA; Cavener DR; Wek RC
    Genetics; 2000 Feb; 154(2):787-801. PubMed ID: 10655230
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Glucose limitation induces GCN4 translation by activation of Gcn2 protein kinase.
    Yang R; Wek SA; Wek RC
    Mol Cell Biol; 2000 Apr; 20(8):2706-17. PubMed ID: 10733573
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Autophosphorylation in the activation loop is required for full kinase activity in vivo of human and yeast eukaryotic initiation factor 2alpha kinases PKR and GCN2.
    Romano PR; Garcia-Barrio MT; Zhang X; Wang Q; Taylor DR; Zhang F; Herring C; Mathews MB; Qin J; Hinnebusch AG
    Mol Cell Biol; 1998 Apr; 18(4):2282-97. PubMed ID: 9528799
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Regulation of translation initiation by amino acids in eukaryotic cells.
    Kimball SR
    Prog Mol Subcell Biol; 2001; 26():155-84. PubMed ID: 11575165
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Histidyl-tRNA synthetase-related sequences in GCN2 protein kinase regulate in vitro phosphorylation of eIF-2.
    Zhu S; Sobolev AY; Wek RC
    J Biol Chem; 1996 Oct; 271(40):24989-94. PubMed ID: 8798780
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Separate domains in GCN1 for binding protein kinase GCN2 and ribosomes are required for GCN2 activation in amino acid-starved cells.
    Sattlegger E; Hinnebusch AG
    EMBO J; 2000 Dec; 19(23):6622-33. PubMed ID: 11101534
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dimerization by translation initiation factor 2 kinase GCN2 is mediated by interactions in the C-terminal ribosome-binding region and the protein kinase domain.
    Qiu H; Garcia-Barrio MT; Hinnebusch AG
    Mol Cell Biol; 1998 May; 18(5):2697-711. PubMed ID: 9566889
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differential requirements for P stalk components in activating yeast protein kinase Gcn2 by stalled ribosomes during stress.
    Gupta R; Hinnebusch AG
    Proc Natl Acad Sci U S A; 2023 Apr; 120(16):e2300521120. PubMed ID: 37043534
    [TBL] [Abstract][Full Text] [Related]  

  • 16. GI domain-mediated association of the eukaryotic initiation factor 2alpha kinase GCN2 with its activator GCN1 is required for general amino acid control in budding yeast.
    Kubota H; Sakaki Y; Ito T
    J Biol Chem; 2000 Jul; 275(27):20243-6. PubMed ID: 10801780
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Uncharged tRNA activates GCN2 by displacing the protein kinase moiety from a bipartite tRNA-binding domain.
    Dong J; Qiu H; Garcia-Barrio M; Anderson J; Hinnebusch AG
    Mol Cell; 2000 Aug; 6(2):269-79. PubMed ID: 10983975
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of positive-acting domains in GCN2 protein kinase required for translational activation of GCN4 expression.
    Wek RC; Ramirez M; Jackson BM; Hinnebusch AG
    Mol Cell Biol; 1990 Jun; 10(6):2820-31. PubMed ID: 2188100
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Phosphorylation of initiation factor 2 alpha by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast.
    Dever TE; Feng L; Wek RC; Cigan AM; Donahue TF; Hinnebusch AG
    Cell; 1992 Feb; 68(3):585-96. PubMed ID: 1739968
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mammalian eukaryotic initiation factor 2 alpha kinases functionally substitute for GCN2 protein kinase in the GCN4 translational control mechanism of yeast.
    Dever TE; Chen JJ; Barber GN; Cigan AM; Feng L; Donahue TF; London IM; Katze MG; Hinnebusch AG
    Proc Natl Acad Sci U S A; 1993 May; 90(10):4616-20. PubMed ID: 8099443
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.