These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

71 related articles for article (PubMed ID: 9435908)

  • 1. Strategies for rapid deconvolution of combinational libraries: comparative evaluation using a model system.
    Konings DA; Wyatt JR; Ecker DJ; Freier SM
    J Med Chem; 1997 Dec; 40(26):4386-95. PubMed ID: 9435908
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Deconvolution of combinatorial libraries for Drug discovery: theoretical comparison of pooling strategies.
    Konings DA; Wyatt JR; Ecker DJ; Freier SM
    J Med Chem; 1996 Jul; 39(14):2710-9. PubMed ID: 8709101
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 'Mutational SURF': a strategy for improving lead compounds identified from combinatorial libraries.
    Freier SM; Konings DA; Wyatt JR; Ecker DJ
    Bioorg Med Chem; 1996 May; 4(5):717-25. PubMed ID: 8804538
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Simulation modeling of pooling for combinatorial protein engineering.
    Polizzi KM; Spencer CU; Dubey A; Matsumura I; Lee JH; Realff MJ; Bommarius AS
    J Biomol Screen; 2005 Dec; 10(8):856-64. PubMed ID: 16234344
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pooling for improved screening of combinatorial libraries for directed evolution.
    Polizzi KM; Parikh M; Spencer CU; Matsumura I; Lee JH; Realff MJ; Bommarius AS
    Biotechnol Prog; 2006; 22(4):961-7. PubMed ID: 16889370
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Deconvolution of combinatorial libraries for drug discovery: experimental comparison of pooling strategies.
    Wilson-Lingardo L; Davis PW; Ecker DJ; Hébert N; Acevedo O; Sprankle K; Brennan T; Schwarcz L; Freier SM; Wyatt JR
    J Med Chem; 1996 Jul; 39(14):2720-6. PubMed ID: 8709102
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Unified QSAR approach to antimicrobials. 4. Multi-target QSAR modeling and comparative multi-distance study of the giant components of antiviral drug-drug complex networks.
    Prado-Prado FJ; Martinez de la Vega O; Uriarte E; Ubeira FM; Chou KC; González-Díaz H
    Bioorg Med Chem; 2009 Jan; 17(2):569-75. PubMed ID: 19112024
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Deconvolution of combinatorial libraries for drug discovery: a model system.
    Freier SM; Konings DA; Wyatt JR; Ecker DJ
    J Med Chem; 1995 Jan; 38(2):344-52. PubMed ID: 7830277
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Strategies for the use of mixture-based synthetic combinatorial libraries: scaffold ranking, direct testing in vivo, and enhanced deconvolution by computational methods.
    Houghten RA; Pinilla C; Giulianotti MA; Appel JR; Dooley CT; Nefzi A; Ostresh JM; Yu Y; Maggiora GM; Medina-Franco JL; Brunner D; Schneider J
    J Comb Chem; 2008; 10(1):3-19. PubMed ID: 18067268
    [No Abstract]   [Full Text] [Related]  

  • 10. Encoding method for OBOC small molecule libraries using a biphasic approach for ladder-synthesis of coding tags.
    Wang X; Zhang J; Song A; Lebrilla CB; Lam KS
    J Am Chem Soc; 2004 May; 126(18):5740-9. PubMed ID: 15125667
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Simulaid: a simulation facilitator and analysis program.
    Mezei M
    J Comput Chem; 2010 Nov; 31(14):2658-68. PubMed ID: 20740566
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A new method for in-silico drug screening and similarity search using molecular dynamics maximum volume overlap (MD-MVO) method.
    Fukunishi Y; Nakamura H
    J Mol Graph Model; 2009 Jan; 27(5):628-36. PubMed ID: 19046907
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Exhaustive mutagenesis in silico: multicoordinate free energy calculations on proteins and peptides.
    Pitera JW; Kollman PA
    Proteins; 2000 Nov; 41(3):385-97. PubMed ID: 11025549
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 2D and 3D spatially addressed arrays for high-throughput automated synthesis of combinatorial libraries.
    Patek M; Safar P; Smrcina M; Wegrzyniak E; Bjergarde K; Weichsel A; Strop P
    J Comb Chem; 2004; 6(1):43-9. PubMed ID: 14714983
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Simulation of non-enzymatic template-directed synthesis of oligonucleotides and peptides.
    Assouline S; Nir S; Lahav N
    J Theor Biol; 2001 Jan; 208(1):117-25. PubMed ID: 11162057
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of novel pyridinopolyamines with potent antimicrobial activity: deconvolution of mixtures synthesized by solution-phase combinatorial chemistry.
    An H; Haly BD; Cook PD
    J Med Chem; 1998 Feb; 41(5):706-16. PubMed ID: 9513599
    [TBL] [Abstract][Full Text] [Related]  

  • 17. An efficient in silico screening method based on the protein-compound affinity matrix and its application to the design of a focused library for cytochrome P450 (CYP) ligands.
    Fukunishi Y; Hojo S; Nakamura H
    J Chem Inf Model; 2006; 46(6):2610-22. PubMed ID: 17125201
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Alternative global goodness metrics and sensitivity analysis: heuristics to check the robustness of conclusions from studies comparing virtual screening methods.
    Sheridan RP
    J Chem Inf Model; 2008 Feb; 48(2):426-33. PubMed ID: 18247505
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis of a positional scanning library of pentamers of N-alkylglycines assisted by microwave activation and validation via the identification of trypsin inhibitors.
    Messeguer J; Cortés N; García-Sanz N; Navarro-Vendrell G; Ferrer-Montiel A; Messeguer A
    J Comb Chem; 2008; 10(6):974-80. PubMed ID: 18847288
    [TBL] [Abstract][Full Text] [Related]  

  • 20. In silico fragment screening by replica generation (FSRG) method for fragment-based drug design.
    Fukunishi Y; Mashimo T; Orita M; Ohno K; Nakamura H
    J Chem Inf Model; 2009 Apr; 49(4):925-33. PubMed ID: 19354203
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.