BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

92 related articles for article (PubMed ID: 9435911)

  • 1. 2-(1-Naphthyloxy)ethylamines with enhanced affinity for human 5-HT1D beta (h5-HT1B) serotonin receptors.
    Ismaiel AM; Dukat M; Law H; Kamboj R; Fan E; Lee DK; Mazzocco L; Buekschkens D; Teitler M; Pierson ME; Glennon RA
    J Med Chem; 1997 Dec; 40(26):4415-9. PubMed ID: 9435911
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Benzylimidazolines as h5-HT1B/1D serotonin receptor ligands: a structure-affinity investigation.
    Law H; Dukat M; Teitler M; Lee DK; Mazzocco L; Kamboj R; Rampersad V; Prisinzano T; Glennon RA
    J Med Chem; 1998 Jun; 41(13):2243-51. PubMed ID: 9632357
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Binding of O-alkyl derivatives of serotonin at human 5-HT1D beta receptors.
    Glennon RA; Hong SS; Bondarev M; Law H; Dukat M; Rakhi S; Power P; Fan E; Kinneau D; Kamboj R; Teitler M; Herrick-Davis K; Smith C
    J Med Chem; 1996 Jan; 39(1):314-22. PubMed ID: 8568822
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and serotonergic activity of 3-[2-(pyrrolidin-1-yl)ethyl]indoles: potent agonists for the h5-HT1D receptor with high selectivity over the h5-HT1B receptor.
    Sternfeld F; Guiblin AR; Jelley RA; Matassa VG; Reeve AJ; Hunt PA; Beer MS; Heald A; Stanton JA; Sohal B; Watt AP; Street LJ
    J Med Chem; 1999 Feb; 42(4):677-90. PubMed ID: 10052975
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Alniditan, a new 5-hydroxytryptamine1D agonist and migraine-abortive agent: ligand-binding properties of human 5-hydroxytryptamine1D alpha, human 5-hydroxytryptamine1D beta, and calf 5-hydroxytryptamine1D receptors investigated with [3H]5-hydroxytryptamine and [3H]alniditan.
    Leysen JE; Gommeren W; Heylen L; Luyten WH; Van de Weyer I; Vanhoenacker P; Haegeman G; Schotte A; Van Gompel P; Wouters R; Lesage AS
    Mol Pharmacol; 1996 Dec; 50(6):1567-80. PubMed ID: 8967979
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 3-(Piperazinylpropyl)indoles: selective, orally bioavailable h5-HT1D receptor agonists as potential antimigraine agents.
    Chambers MS; Street LJ; Goodacre S; Hobbs SC; Hunt P; Jelley RA; Matassa VG; Reeve AJ; Sternfeld F; Beer MS; Stanton JA; Rathbone D; Watt AP; MacLeod AM
    J Med Chem; 1999 Feb; 42(4):691-705. PubMed ID: 10052976
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Agonistic properties of alniditan, sumatriptan and dihydroergotamine on human 5-HT1B and 5-HT1D receptors expressed in various mammalian cell lines.
    Lesage AS; Wouters R; Van Gompel P; Heylen L; Vanhoenacker P; Haegeman G; Luyten WH; Leysen JE
    Br J Pharmacol; 1998 Apr; 123(8):1655-65. PubMed ID: 9605573
    [TBL] [Abstract][Full Text] [Related]  

  • 8. SB-224289--a novel selective (human) 5-HT1B receptor antagonist with negative intrinsic activity.
    Selkirk JV; Scott C; Ho M; Burton MJ; Watson J; Gaster LM; Collin L; Jones BJ; Middlemiss DN; Price GW
    Br J Pharmacol; 1998 Sep; 125(1):202-8. PubMed ID: 9776361
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The binding of propranolol at 5-hydroxytryptamine1D beta T355N mutant receptors may involve formation of two hydrogen bonds to asparagine.
    Glennon RA; Dukat M; Westkaemper RB; Ismaiel AM; Izzarelli DG; Parker EM
    Mol Pharmacol; 1996 Jan; 49(1):198-206. PubMed ID: 8569707
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The selective 5-HT1B receptor inverse agonist 1'-methyl-5-[[2'-methyl-4'-(5-methyl-1,2, 4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydro- spiro[furo[2,3-f]indole-3,4'-piperidine] (SB-224289) potently blocks terminal 5-HT autoreceptor function both in vitro and in vivo.
    Gaster LM; Blaney FE; Davies S; Duckworth DM; Ham P; Jenkins S; Jennings AJ; Joiner GF; King FD; Mulholland KR; Wyman PA; Hagan JJ; Hatcher J; Jones BJ; Middlemiss DN; Price GW; Riley G; Roberts C; Routledge C; Selkirk J; Slade PD
    J Med Chem; 1998 Apr; 41(8):1218-35. PubMed ID: 9548813
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 5-HT1D receptor agonist properties of novel 2-[5-[[(trifluoromethyl)sulfonyl]oxy]indolyl]ethylamines and their use as synthetic intermediates.
    Barf TA; de Boer P; Wikström H; Peroutka SJ; Swensson K; Ennis MD; Ghazal NB; McGuire JC; Smith MW
    J Med Chem; 1996 Nov; 39(24):4717-26. PubMed ID: 8941384
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cloning and pharmacological characterization of a novel human 5-hydroxytryptamine1D receptor subtype.
    Veldman SA; Bienkowski MJ
    Mol Pharmacol; 1992 Sep; 42(3):439-44. PubMed ID: 1328844
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterization of the aminomethylchroman derivative BAY x 3702 as a highly potent 5-hydroxytryptamine1A receptor agonist.
    De Vry J; Schohe-Loop R; Heine HG; Greuel JM; Mauler F; Schmidt B; Sommermeyer H; Glaser T
    J Pharmacol Exp Ther; 1998 Mar; 284(3):1082-94. PubMed ID: 9495870
    [TBL] [Abstract][Full Text] [Related]  

  • 14. SB-216641 and BRL-15572--compounds to pharmacologically discriminate h5-HT1B and h5-HT1D receptors.
    Price GW; Burton MJ; Collin LJ; Duckworth M; Gaster L; Göthert M; Jones BJ; Roberts C; Watson JM; Middlemiss DN
    Naunyn Schmiedebergs Arch Pharmacol; 1997 Sep; 356(3):312-20. PubMed ID: 9303567
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 3-[2-(Pyrrolidin-1-yl)ethyl]indoles and 3-[3-(piperidin-1-yl)propyl]indoles: agonists for the h5-HT1D receptor with high selectivity over the h5-HT1B subtype.
    Castro JL; Street LJ; Guiblin AR; Jelley RA; Russell MG; Sternfeld F; Beer MS; Stanton JA; Matassa VG
    J Med Chem; 1997 Oct; 40(22):3497-500. PubMed ID: 9357514
    [No Abstract]   [Full Text] [Related]  

  • 16. Actions of roxindole at recombinant human dopamine D2, D3 and D4 and serotonin 5-HT1A, 5-HT1B and 5-HT1D receptors.
    Newman-Tancredi A; Cussac D; Audinot V; Millan MJ
    Naunyn Schmiedebergs Arch Pharmacol; 1999 Jun; 359(6):447-53. PubMed ID: 10431754
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Characterization of human serotonin 1D and 1B receptors using [3H]-GR-125743, a novel radiolabelled serotonin 5HT1D/1B receptor antagonist.
    Doménech T; Beleta J; Palacios JM
    Naunyn Schmiedebergs Arch Pharmacol; 1997 Sep; 356(3):328-34. PubMed ID: 9303569
    [TBL] [Abstract][Full Text] [Related]  

  • 18. N-Methyl-5-tert-butyltryptamine: A novel, highly potent 5-HT1D receptor agonist.
    Xu YC; Schaus JM; Walker C; Krushinski J; Adham N; Zgombick JM; Liang SX; Kohlman DT; Audia JE
    J Med Chem; 1999 Feb; 42(3):526-31. PubMed ID: 9986723
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A single amino-acid difference confers major pharmacological variation between human and rodent 5-HT1B receptors.
    Oksenberg D; Marsters SA; O'Dowd BF; Jin H; Havlik S; Peroutka SJ; Ashkenazi A
    Nature; 1992 Nov; 360(6400):161-3. PubMed ID: 1436092
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Modified ligand binding to the naturally occurring Cys-124 variant of the human serotonin 5-HT1B receptor.
    Brüss M; Bönisch H; Bühlen M; Nöthen MM; Propping P; Göthert M
    Pharmacogenetics; 1999 Feb; 9(1):95-102. PubMed ID: 10208648
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.